Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Carbamoyl phosphate is an anion of biochemical significance. In land-dwelling animals, it is an intermediary metabolite in nitrogen disposal through the urea cycle and the synthesis of pyrimidines. Its enzymatic counterpart, carbamoyl phosphate synthetase I (CPS I), interacts with a class of molecules called sirtuins, NAD dependent protein deacetylases, and ATP to form carbamoyl phosphate. CP then enters the urea cycle in which it reacts with ornithine (a process catalyzed by the enzyme ornithine transcarbamylase) to form citrulline.
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Carbamoylphosphate is an anion of biochemical significance. In land-dwelling animals, it is an intermediary metabolite in nitrogen disposal through the...
Carbamoylphosphate synthetase catalyzes the ATP-dependent synthesis of carbamoylphosphate from glutamine (EC 6.3.5.5) or ammonia (EC 6.3.4.16) and bicarbonate...
Carbamoylphosphate synthetase I (CPS I) is a ligase enzyme located in the mitochondria involved in the production of urea. Carbamoylphosphate synthetase...
Carbamoylphosphate synthetase (glutamine-hydrolysing) (EC 6.3.5.5) is an enzyme that catalyzes the reactions that produce carbamoylphosphate in the cytosol...
the condensation of L-aspartate and carbamoylphosphate to form N-carbamoyl-L-aspartate and inorganic phosphate. The catalysis by ATCase serves as the...
Carbamoylphosphate synthetase I deficiency (CPS I deficiency) is an autosomal recessive metabolic disorder that causes ammonia to accumulate in the blood...
Carbamoylphosphate synthetase III (CPS III) is one of the three isoforms of the carbamoylphosphate synthetase, an enzyme that catalyzes the active production...
that catalyzes the reaction between carbamoylphosphate (CP) and ornithine (Orn) to form citrulline (Cit) and phosphate (Pi). There are two classes of OTC:...
that catalyzes the chemical reaction carbamoylphosphate + putrescine ⇌ {\displaystyle \rightleftharpoons } phosphate + N-carbamoylputrescine Thus, the two...
of carbamoylphosphate H2N−C(=O)−O−PO2−3: ATP + NH3 + CO2 ⇌ ADP + H2N−C(=O)−O−PO2−3 An important example of an enzyme with this activity is carbamoyl phosphate...
of chili peppers Carbamoylphosphate synthase II, an enzyme that catalyzes a reaction yielding carbamoylphosphateCarbamoylphosphate synthetase, an enzyme...
is converted into carbamoylphosphate through the investment of two ATP molecules. This step is facilitated by carbamoylphosphate synthetase I. The second...
of carbamoylphosphate from glutamine and CO2. Next, aspartate carbamoyltransferase catalyzes a condensation reaction between aspartate and carbamoyl phosphate...
CAD protein (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) is a trifunctional multi-domain enzyme involved in the...
converts carbamoyl aspartic acid into 4,5-dihydroorotic acid in the biosynthesis of pyrimidines. It forms a multifunctional enzyme with carbamoylphosphate synthetase...
into carbamoylphosphate (H 2NC(O)OPO2− 3) by carbamoylphosphate synthetase. Ornithine transcarbamylase catalyzes the reaction between carbamoyl phosphate...
negligible, as is the case with N-acetylglutamate's activity on carbamoylphosphate synthetase I, for example. A non-regulatory allosteric site is any...
System 1 Parry Sound Harbour Water Aerodrome, the IATA airport code Carbamoylphosphate synthase This disambiguation page lists articles associated with...
reaction carbamoylphosphate + oxamate ⇌ {\displaystyle \rightleftharpoons } phosphate + oxalureate Thus, the two substrates of this enzyme are carbamoyl phosphate...
The biosynthesis of cyanide in the NiFe hydrogenases proceeds from carbamoylphosphate, which converts to cysteinyl thiocyanate, the CN− donor. The cyanide...
that catalyzes the chemical reaction carbamoylphosphate + L-lysine ⇌ {\displaystyle \rightleftharpoons } phosphate + L-homocitrulline Thus, the two substrates...
build-up in the bloodstream. Ammonia is converted to carbamoylphosphate by the enzyme carbamoylphosphate synthetase, and then enters the urea cycle to be...
the proximal portion of the urea cycle, responsible for converting carbamoylphosphate and ornithine into citrulline. OTC deficiency is inherited in an...
Man (OMIM): 237300 - hyperammonemia due to carbamoylphosphate synthetase I deficiency (carbamoylphosphate synthetase I) Online Mendelian Inheritance...
Ornithine translocase deficiency, also called hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome, is a rare autosomal recessive urea cycle...