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BK virus information


BK virus
Cytology of a polyomavirus infected cell, using Papanicolaou stain. The high nuclear to cytoplasmic ratio makes it resemble cancer (thus the name "decoy cell") but the inclusion body reveals its viral pathophysiology.
SpecialtyInfectious disease

The BK virus, also known as Human polyomavirus 1, is a member of the polyomavirus family. Past infection with the BK virus is widespread,[1] but significant consequences of infection are uncommon, with the exception of the immunocompromised and the immunosuppressed. BK virus is an abbreviation of the name of the first patient, from whom the virus was isolated in 1971 (the patient was then 29 years old).

  1. ^ Tagliapietra A, Rotondo JC, Bononi I, Mazzoni E, Magagnoli F, Maritati M, Contini C, Vesce F, Tognon M, Martini F (2019). "Footprints of BK and JC polyomaviruses in specimens from females affected by spontaneous abortion". Hum Reprod. 34 (3): 433–440. doi:10.1093/humrep/dey375. hdl:11392/2397214. PMID 30590693. S2CID 58621197.

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BK virus

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The BK virus, also known as Human polyomavirus 1, is a member of the polyomavirus family. Past infection with the BK virus is widespread, but significant...

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BK

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(IATA airline code BK) BK channel, an ion channel characterized by its large conductance of potassium ions through cell membranes BK virus, a member of the...

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Slow virus

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BK virus), or, in the case of prions, the identity of the agent involved. Slow viruses cause a variety of diseases, including cancer. §JC virus & BK virus...

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Polyomaviridae

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populations studied. BK virus is associated with nephropathy in renal transplant and non-renal solid organ transplant patients, JC virus with progressive...

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Decoy cells

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leukoencephalopathy (JC virus) and polyomavirus-associated nephropathy, ureteral stenosis and hemorrhagic cystitis (BK virus). The latter condition mainly...

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Leflunomide

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increased demand on pyrimidines in these faster growing cells. Polyoma BK virus nephropathy Kimura's disease Systemic lupus erythematosus Felty's syndrome...

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Waterborne disease

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of the digestive tract. Various other waterborne diseases are caused by viruses. Yet other important classes of waterborne diseases are caused by metazoan...

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Viral disease

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infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells. Examples...

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List of infectious diseases

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Weaver, S. C. (2012). "A vaccine candidate for eastern equine encephalitis virus based on IRES-mediated attenuation". Vaccine. 30 (7): 1276–1282. doi:10...

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Immunosuppression

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T-cells. Immunosuppressive drug Discovery and development of mTOR inhibitors BK virus Interleukin-2 immunotherapy B cell deficiency T cell deficiency Treatment...

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Progressive multifocal leukoencephalopathy

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announced it is launching a clinical trial for the treatment of PML utilizing BK virus specific T-cells (VSTs). One-third to one-half of people with PML die in...

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Regenerative medicine advanced therapy

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Allovir allogeneic CAR-T BK virus, CMV, adenoviridae, Epstein–Barr virus, human herpesvirus 6, JC virus (human polyomavirus 2) BK virus associated hemorrhagic...

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Lung cancer

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namely human papillomaviruses, BK virus, JC virus, human cytomegalovirus, SV40, measles virus, and Torque teno virus – in lung cancer development has...

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Cidofovir

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abundance of safer alternatives such as aciclovir. Cidofovir shows anti-BK virus activity in a subgroup of transplant recipients. Cidofovir is being investigated...

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Kidney transplantation

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transplants and is a risk factor for graft failure or acute rejection. BK virus is now being increasingly recognised as a transplant risk factor which...

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Immunosuppressive drug

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subpopulations in tissues using immunohistochemistry. Immunosuppression BK virus Behcet's Disease Discovery and development of mTOR inhibitors Treatment...

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Glomerulosclerosis

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patients will need to control their cholesterol through diet or both diet and medicine. BK virus Epstein–Barr virus infection Glomerulosclerosis--WebMD...

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Hemorrhagic cystitis

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acute viral hemorrhagic cystitis in children, though it can result from BK virus as well. A chemical hemorrhagic cystitis can develop when vaginal products...

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Human polyomavirus 2

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Human polyomavirus 2, commonly referred to as the JC virus or John Cunningham virus, is a type of human polyomavirus (formerly known as papovavirus). It...

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Martin Paul Eve

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suffers from severe rheumatoid arthritis and end-stage renal failure due to BK virus nephropathy. Eve's academic work focuses on contemporary American and British...

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Hepatitis C virus

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C virus (HCV) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is...

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Respiratory syncytial virus

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Respiratory syncytial virus (RSV), also called human respiratory syncytial virus (hRSV) and human orthopneumovirus, is a contagious virus that causes infections...

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Agnoprotein

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disease, BK virus and JC virus, as well as the simian polyomavirus SV40. Agnoprotein is typically quite short: examples from BK virus, JC virus, and SV40...

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Marburg virus

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Marburg virus (MARV) is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus...

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Mycophenolic acid

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infections, including shingles, other herpes infections, cytomegalovirus, and BK virus associated nephropathy. In addition the FDA is investigating[when?] 16...

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