Species of filamentous virus responsible for hemorrhagic fever
For the genus, see Marburgvirus.
Marburg virus
Transmission electron micrograph of Marburg virus
Virus classification
(unranked):
Virus
Realm:
Riboviria
Kingdom:
Orthornavirae
Phylum:
Negarnaviricota
Class:
Monjiviricetes
Order:
Mononegavirales
Family:
Filoviridae
Genus:
Marburgvirus
Species:
Marburg marburgvirus
Virus:
Marburg virus
Marburg virus (MARV) is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus.[1] It causes Marburg virus disease in primates, a form of viral hemorrhagic fever.[2] The virus is considered to be extremely dangerous. The World Health Organization (WHO) rates it as a Risk Group 4 Pathogen (requiring biosafety level 4-equivalent containment).[3] In the United States, the National Institute of Allergy and Infectious Diseases ranks it as a Category A Priority Pathogen[4] and the Centers for Disease Control and Prevention lists it as a Category A Bioterrorism Agent.[5] It is also listed as a biological agent for export control by the Australia Group.[6]
The virus can be transmitted by exposure to one species of fruit bats or it can be transmitted between people via body fluids through unprotected sex and broken skin. The disease can cause haemorrhage, fever, and other symptoms similar to Ebola, which belongs to the same family of viruses. According to the WHO, there are no approved vaccines or antiviral treatment for Marburg, but early, professional treatment of symptoms like dehydration considerably increases survival chances.[7]
In 2009, expanded clinical trials of an Ebola and Marburg vaccine began in Kampala, Uganda.[8][9]
^Cite error: The named reference KuhnArch was invoked but never defined (see the help page).
^Spickler A. "Ebolavirus and Marburgvirus Infections" (PDF).
^US Department of Health and Human Services. "Biosafety in Microbiological and Biomedical Laboratories (BMBL) 5th Edition". Retrieved 2011-10-16.
^"Biodefense Category A, B, C Pathogens, NIAID, NIH". Archived from the original on 2011-10-22. Retrieved 2011-10-16.
^US Centers for Disease Control and Prevention (CDC). "Bioterrorism Agents/Diseases". Archived from the original on 2014-07-22. Retrieved 2011-10-16.
^The Australia Group. "List of Biological Agents for Export Control". Archived from the original on 2011-08-06. Retrieved 2011-10-16.
^Marburg virus disease Fact sheet Updated October 2017 http://www.who.int/mediacentre/factsheets/fs_marburg/en/
^Beth Skwarecki Ebola, Marburg DNA Vaccines Prove Safe in Phase 1 Trial Medscape Medical News, September 17, 2014
^Evaluating an Ebola and a Marburg Vaccine in Uganda U.S. Department of Health & Human Services
Marburgvirus (MARV) is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus...
Marburgvirus disease (MVD; formerly Marburg hemorrhagic fever) is a viral hemorrhagic fever in human and non-human primates caused by either of the two...
Marburg (German pronunciation: [ˈmaːɐ̯bʊʁk] or [ˈmaʁbʊʁk] ) is a university town in the German federal state (Bundesland) of Hesse, capital of the Marburg-Biedenkopf...
National Park, Kenya. In the 1980s, two European visitors contracted Marburgvirus disease there. It is one of five named "elephant caves" of Mount Elgon...
Institute of Tropical Medicine, Piot was part of a team that observed a Marburg-like virus in a sample of blood taken from a sick nun working in Zaire. Piot...
The 1967 Marburgvirus outbreak was the first recorded outbreak of Marburgvirus disease. It started in early August 1967 when 30 people became ill in...
in the Hot Zone". The filoviruses—including Ebola virus, Sudan virus, Marburgvirus, and Ravn virus—are Biosafety Level 4 agents, extremely dangerous...
bat-borne viruses are considered important emerging viruses. These zoonotic viruses include the rabies virus, SARS-CoV, MERS-CoV, Marburgvirus, Nipah virus, and...
"strain" of the closely related Marburgvirus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species...
negative-sense RNA viruses in the order Mononegavirales. Two members of the family that are commonly known are Ebola virus and Marburgvirus. Both viruses, and some...
majority of people with filoviral hemorrhagic fevers (e.g., Ebola and Marburgvirus), Crimean–Congo hemorrhagic fever (CCHF), and the South American hemorrhagic...
case of Ebola-like Marburgvirus". Reuters. 7 August 2021. Retrieved 7 August 2021. "West Africa's first-ever case of Marburgvirus disease confirmed in...
of Marburg marburgvirus, whose members are the two known marburgviruses, Marburgvirus (MARV) and Ravn virus (RAVV). Both viruses cause Marburgvirus disease...
Kurth, R.; Bukreyev, A. (1999). "Characteristics of Filoviridae: Marburg and Ebola viruses". Die Naturwissenschaften. 86 (1): 8–17. Bibcode:1999NW.....86...
days." The virus responsible for the initial outbreak, first thought to be the Marburgvirus, was later identified as a new type of virus related to the...
February 2023 and, on 13 February 2023, it was identified as being Marburgvirus disease. It was the first time the disease was detected in the country...
Cuevavirus. LLOV is a distant relative of the commonly known Ebola virus and Marburgvirus. The species Lloviu cuevavirus is a virological taxon (i.e. a man-made...
of Kinshasa. The virus responsible for the initial outbreak, named after the nearby Ebola River, was first thought to be Marburgvirus but was later identified...
Archived (PDF) from the original on 30 August 2019. "Outbreak Table | Marburg Hemorrhagic Fever | CDC". "Dengue in the Americas: The Epidemics of 2000"...
the family Filoviridae with two specific genera: Ebola-like viruses and Marburg-like viruses. This proposal was implemented in Washington, D.C., as of April...
genomes. Ebola and Marburgviruses are well known members of this group, along with influenza virus, measles, mumps and rabies. All viruses that encode a reverse...
genus Flavivirus, which also contains the Zika virus, dengue virus, and yellow fever virus. The virus is primarily transmitted by mosquitoes, mostly species...
Nipah virus is a bat-borne, zoonotic virus that causes Nipah virus infection in humans and other animals, a disease with a very high mortality rate (40-75%)...
Reston virus (RESTV) is one of six known viruses within the genus Ebolavirus. Reston virus causes Ebola virus disease in non-human primates; unlike the...
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