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Autologous conditioned serum information


Autologous conditioned serum, also known as Orthokine and Regenokine, is an experimental procedure in which a person's own blood is extracted, manipulated, and then reintroduced with claimed benefit in osteoarthritis.[1] There is limited evidence on safety and effectiveness as of 2017.[1] It is not included in medical guidelines as of 2017.[1] It is a type of autologous blood therapy.[1]

  1. ^ a b c d Wehling, P; Evans, C; Wehling, J; Maixner, W (August 2017). "Effectiveness of intra-articular therapies in osteoarthritis: a literature review". Therapeutic Advances in Musculoskeletal Disease. 9 (8): 183–196. doi:10.1177/1759720X17712695. PMC 5557186. PMID 28835778. Limited data due to less expanded use and nonconsideration in guidelines.

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Autologous conditioned serum

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Autologous conditioned serum, also known as Orthokine and Regenokine, is an experimental procedure in which a person's own blood is extracted, manipulated...

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Autologous blood therapy

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centrifugation. Forms include platelet-rich plasma (PRP), and autologous conditioned serum (ACS). It is possible that ozonated or UV autohemotherapy may...

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Treatment of equine lameness

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anti-inflammatory cytokines, including IRAP. The resulting serum, known as autologous conditioned serum (ACS), is then centrifuged to produce enough ACS for...

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Autoimmune urticaria

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study by Sabroe et al. in 1999 showed that intradermal injection of autologous serum caused a wheal and flare reaction (a hallmark of urticaria) in a majority...

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Dry eye syndrome

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superior to others in treating dry eye. Eye drops that include autologous serum (serum taken from the same person's blood and used in an eye drop formulation)...

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Myasthenia gravis

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10% of people with generalized MG are considered treatment-refractory. Autologous hematopoietic stem cell transplantation (HSCT) is sometimes used in severe...

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Multiple myeloma

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detecting a myeloma protein on serum protein electrophoresis tests done for other purposes. MGUS is a relatively stable condition afflicting 3% of people aged...

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Chronic inflammatory demyelinating polyneuropathy

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cases of CIDP, when second-line immunomodulatory drugs are not efficient, autologous hematopoietic stem cell transplantation (HSCT) is sometimes performed...

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Cerebrospinal fluid leak

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uses blood's clotting factors to clot the sites of holes. The volume of autologous blood and number of patch attempts for patients is highly variable. One-quarter...

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Blood type

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possible to use the patient's own blood for transfusion. This is called autologous blood transfusion, which is always compatible with the patient. The procedure...

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Neurotrophic keratitis

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Other approaches used in severe forms include the administration of autologous serum eye drops. Research studies have focused on developing novel treatments...

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Plasma cell leukemia

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include a proteasome inhibitor drug, particularly bortezomib, and/or autologous stem-cell transplantation have improved pPCL survival. For example, 28...

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Cortisol

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(January 1982). "Hydrocortisone abrogates proliferation of T cells in autologous mixed lymphocyte reaction by rendering the interleukin-2 Producer T cells...

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Blood doping

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supplements, are usually required for patients undergoing autologous donations. Nearly 50% of autologous donations are not used by the donor and are discarded...

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Monoclonal gammopathy of renal significance

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MGRS. Serum protein electrophoresis, urine protein electrophoresis (UPEP), serum and urine immunofixation, serum free light chain assay, serum free light...

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Stem cell

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just after birth. Of all stem cell types, autologous harvesting involves the least risk. By definition, autologous cells are obtained from one's own body...

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Ocular neuropathic pain

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publications have shown that neuro-regenerative therapies such as 20% autologous serum eye drops and topical nerve growth factor, and anti-inflammatory agents...

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Systemic scleroderma

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systemic disease, but neither has been subjected to large clinical trials. Autologous hematopoietic stem cell transplantation (HSCT) is based on the assumption...

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Monoclonal immunoglobulin deposition disease

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the monoclonal proteins and may include bortezomib-based treatment, an autologous stem cell transplant, and if the patient is considered eligible, an organ...

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Follicular lymphoma

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initial treatment) or multiple relapses have also been treated with either autologous (i.e. stem cells taken from patient) or allogeneic (i.e. stem cells taken...

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Superior limbic keratoconjunctivitis

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cases, potential treatments include topical ciclosporin A, vitamin A, autologous serum and injections of triamcinolone. Surgical treatment options include...

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Cornea

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such as Stevens Johnson Syndrome, persistent corneal ulcer etc., the autologous contralateral (normal) suprabasal limbus derived in vitro expanded corneal...

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Cytokine release syndrome

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Adoptive cell transfer of autologous T-cells modified with chimeric antigen receptors (CAR-T cell therapy) also causes CRS. Serum samples of patients with...

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Embryonic stem cell

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on fibroblasts treated with mitomycin-c in a medium containing serum and conditioned by ES cells. After approximately one week, colonies of cells grew...

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Therapy

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cell transfer therapy autologous immune enhancement therapy TK cell therapy by humoral immune factors: antibody therapy by whole serum: serotherapy, including...

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Solar urticaria

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radiation. When patients with SU were injected with an irradiated autologous serum, many developed urticaria within the area of injection. When people...

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