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Apoptosis inhibitor of macrophage information


Apoptosis inhibitor of macrophage (AIM) is a protein produced by macrophages that regulates immune responses and inflammation. It plays a crucial role in key intracellular processes like lipid metabolism and apoptosis.

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Apoptosis inhibitor of macrophage

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Apoptosis inhibitor of macrophage (AIM) is a protein produced by macrophages that regulates immune responses and inflammation. It plays a crucial role...

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AIM

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satellite Ancestry-informative marker, in genetics Apoptosis inhibitor of macrophage, a macrophage-derived protein Asteroid Impact Mission, a cancelled...

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Macrophage

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lysosomal action, thereby using macrophages for their own replication and causing macrophage apoptosis. Macrophages can digest more than 100 bacteria...

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Selective serotonin reuptake inhibitor

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Coprescription of Triptan Antimigraine Drugs and Selective Serotonin Reuptake Inhibitor or Selective Norepinephrine Reuptake Inhibitor Antidepressants...

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Apoptosis

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Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized: apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms...

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Cancer immunotherapy

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Antibody BGB-A317 is a PD-1 inhibitor (designed to not bind Fc gamma receptor I) in early clinical trials. In May 2016, PD-L1 inhibitor atezolizumab was approved...

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Macrophage migration inhibitory factor

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Macrophage migration inhibitory factor (MIF), also known as glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, or phenylpyruvate tautomerase...

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Alveolar macrophage

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alveolar macrophage, pulmonary macrophage, (or dust cell) is a type of macrophage, a professional phagocyte, found in the airways and at the level of the alveoli...

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Immunosuppressive drug

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neutrophils, macrophages, and mastocytes. Cytostatics inhibit cell division. In immunotherapy, they are used in smaller doses than in the treatment of malignant...

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Transforming growth factor beta

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activates apoptosis signal-inducing kinase 1 (ASK1), which goes on to activate the Jun amino-terminal kinase (JNK) pathway and thus apoptosis as seen in...

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CD5L

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CD5 antigen-like is a protein (also known as AIM Apoptosis Inhibitor of Macrophages) that in humans is encoded by the CD5L gene. GRCh38: Ensembl release...

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Phagocyte

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amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life. Phagocytes of humans and other animals...

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T helper cell

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the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages and neutrophils. CD4+ cells...

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Necrosis

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digestion of cell components. In contrast, apoptosis is a naturally occurring programmed and targeted cause of cellular death. While apoptosis often provides...

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Tumor necrosis factor

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to inhibit apoptosis in activated HSCs, an activity which should, in principle, induce fibrosis. Specifically, TNFα produced by hepatic macrophages is...

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Mycobacterium tuberculosis

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play in, and the apoptotic pathway in macrophages are controlled in this manner. As a result of having apoptosis being suppressed, it provides M. tuberculosis...

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Autoinflammatory diseases

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by a particular mutation or signal. Excessive activation of neutrophils, monocytes/macrophages, and dendritic cells leads to auto-inflammatory symptoms...

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Necroptosis

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undergo apoptosis, such as during viral infection in which apoptosis signaling proteins are blocked by the virus. Cell suicide is an effective means of stemming...

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Wound healing

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life-spans of around two days, so they usually undergo apoptosis once they have completed their tasks and are engulfed and degraded by macrophages. Other...

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Innate immune system

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or inhibit growth of bacteria and fungi. Similar to macrophages, neutrophils attack pathogens by activating a respiratory burst. The main products of the...

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Haematopoiesis

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and inflammation during adulthood. Splenic macrophages and adhesion molecules may be involved in regulation of extramedullary myeloid cell generation in...

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Cytokine

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needed]. Cytokines are produced by a broad range of cells, including immune cells like macrophages, B lymphocytes, T lymphocytes and mast cells, as well...

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Dermal macrophage

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Dermal macrophages are macrophages in the skin that facilitate skin homeostasis by mediating wound repair, hair growth, and salt balance. Their functional...

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Serpin

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"Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing...

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Ischemic cell death

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Clinical implications of apoptosis in ischemic myocardium. Current problems in cardiology, 31(3), 181-264. Majno; Joris (1995). "Apoptosis, oncosis, and necrosis...

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Genistein

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that structurally belongs to a class of compounds known as isoflavones. It is described as an angiogenesis inhibitor and a phytoestrogen. It was first isolated...

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