Apoptosis inhibitor of macrophage (AIM) is a protein produced by macrophages that regulates immune responses and inflammation. It plays a crucial role in key intracellular processes like lipid metabolism and apoptosis.
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satellite Ancestry-informative marker, in genetics Apoptosisinhibitorofmacrophage, a macrophage-derived protein Asteroid Impact Mission, a cancelled...
lysosomal action, thereby using macrophages for their own replication and causing macrophageapoptosis. Macrophages can digest more than 100 bacteria...
Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized: apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms...
Antibody BGB-A317 is a PD-1 inhibitor (designed to not bind Fc gamma receptor I) in early clinical trials. In May 2016, PD-L1 inhibitor atezolizumab was approved...
Macrophage migration inhibitory factor (MIF), also known as glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, or phenylpyruvate tautomerase...
alveolar macrophage, pulmonary macrophage, (or dust cell) is a type ofmacrophage, a professional phagocyte, found in the airways and at the level of the alveoli...
neutrophils, macrophages, and mastocytes. Cytostatics inhibit cell division. In immunotherapy, they are used in smaller doses than in the treatment of malignant...
activates apoptosis signal-inducing kinase 1 (ASK1), which goes on to activate the Jun amino-terminal kinase (JNK) pathway and thus apoptosis as seen in...
CD5 antigen-like is a protein (also known as AIM ApoptosisInhibitorofMacrophages) that in humans is encoded by the CD5L gene. GRCh38: Ensembl release...
amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life. Phagocytes of humans and other animals...
the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages and neutrophils. CD4+ cells...
digestion of cell components. In contrast, apoptosis is a naturally occurring programmed and targeted cause of cellular death. While apoptosis often provides...
to inhibitapoptosis in activated HSCs, an activity which should, in principle, induce fibrosis. Specifically, TNFα produced by hepatic macrophages is...
play in, and the apoptotic pathway in macrophages are controlled in this manner. As a result of having apoptosis being suppressed, it provides M. tuberculosis...
by a particular mutation or signal. Excessive activation of neutrophils, monocytes/macrophages, and dendritic cells leads to auto-inflammatory symptoms...
undergo apoptosis, such as during viral infection in which apoptosis signaling proteins are blocked by the virus. Cell suicide is an effective means of stemming...
life-spans of around two days, so they usually undergo apoptosis once they have completed their tasks and are engulfed and degraded by macrophages. Other...
or inhibit growth of bacteria and fungi. Similar to macrophages, neutrophils attack pathogens by activating a respiratory burst. The main products of the...
and inflammation during adulthood. Splenic macrophages and adhesion molecules may be involved in regulation of extramedullary myeloid cell generation in...
needed]. Cytokines are produced by a broad range of cells, including immune cells like macrophages, B lymphocytes, T lymphocytes and mast cells, as well...
Dermal macrophages are macrophages in the skin that facilitate skin homeostasis by mediating wound repair, hair growth, and salt balance. Their functional...
Clinical implications ofapoptosis in ischemic myocardium. Current problems in cardiology, 31(3), 181-264. Majno; Joris (1995). "Apoptosis, oncosis, and necrosis...
that structurally belongs to a class of compounds known as isoflavones. It is described as an angiogenesis inhibitor and a phytoestrogen. It was first isolated...