An antipyretic (/ˌæntipaɪˈrɛtɪk/, from anti- 'against' and pyretic 'feverish') is a substance that reduces fever.[1] Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which results in a reduction in fever.
Most antipyretic medications have other purposes. The most common antipyretics in the US are usually ibuprofen and aspirin, which are nonsteroidal anti-inflammatory drugs (NSAIDs) used primarily as anti-inflammatories and analgesics (pain relievers), but which also have antipyretic properties; and paracetamol (acetaminophen), an analgesic without anti-inflammatory properties.[2]
There is some debate over the appropriate use of such medications, since fever is part of the body's immune response to infection.[3][4] A study published by the Royal Society claims that fever suppression causes at least 1% more influenza deaths in the United States, or 700 extra deaths per year.[5]
^"Definition of antipyretic". Merriam-Webster Online Dictionary. Retrieved 2007-12-19.
^"Acetaminophen," National Center for Biotechnology Information, U.S. National Library of Medicine. Modified 2016-08-07, Accessed 2016-08-16.
^"Mayo Clinic".
^"Medline Plus".
^Kupferschmidt, Kai (2014-01-21). "Fight the Flu, Hurt Society?". ScienceNow.
An antipyretic (/ˌæntipaɪˈrɛtɪk/, from anti- 'against' and pyretic 'feverish') is a substance that reduces fever. Antipyretics cause the hypothalamus...
class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin...
hyperthermia as hyperthermia may quickly lead to death and does not respond to antipyretic medications. The distinction may however be difficult to make in an emergency...
Paracetamol (acetaminophen) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely used over the...
isopropylantipyrine in Japan) is a derivative of phenazone with similar analgesic and antipyretic effects. Originally patented in 1931, propyphenazone is marketed as a...
action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also...
Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic used in horses, cattle and pigs. It is often formulated as the meglumine...
was the first aniline derivative found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the...
antipyrine (USAN), antipyrin, or analgesine) is an analgesic (pain reducing), antipyretic (fever reducing) and anti-inflammatory drug. While it predates the term...
it is available. Metamizole, with its potent analgesic (pain relief), antipyretic (reduce fever), and spasmolytic (relax muscle contractions) properties...
in der Weidenrinde entdeckte alcaloidische Substanz" [On Rigatelli's antipyretic [i.e., anti-fever drug] and on an alkaloid substance discovered in willow...
inhibits two isoforms of cyclooxygenase, COX-1 and COX-2. The analgesic, antipyretic, and anti-inflammatory activity of NSAIDs appears to operate mainly through...
Environmental xenobiotics are xenobiotic compounds with a biological activity that are found as pollutants in the natural environment. Pharmaceutical drugs...
Asante, Du-Bois; et al. (2019). "Anti-inflammatory, anti-nociceptive and antipyretic activity of young and old leaves of Vernonia amygdalina". Biomedicine...
oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral and parenteral formulations...
of essential medicines. A sampling of classes of medicine includes: Antipyretics: reducing fever (pyrexia/pyresis) Analgesics: reducing pain (painkillers)...
primary mechanism of action responsible for ketorolac's anti-inflammatory, antipyretic, and analgesic effects is the inhibition of prostaglandin synthesis by...
credited with some of neem oil's properties as an antiseptic, antifungal, antipyretic and antihistamine. Neem oil has a history of use in Ayurvedic folk medicine...
nonsteroidal anti-inflammatory drug (NSAID). It also has analgesic, antipyretic, and platelet-inhibitory actions. It is used primarily in the treatment...
student Michael Sveda. Sveda was working in the lab on the synthesis of an antipyretic drug. He put his cigarette down on the lab bench, and when he put it...
prescriptions. As an NSAID, indometacin is an analgesic, anti-inflammatory, and antipyretic. Clinical indications for indometacin include: Joint diseases rheumatoid...
of a variety of alkaloids, the most familiar of which is quinine, an antipyretic (antifever) agent especially useful in treating malaria. For a while...
such, is a non-selective COX inhibitor possessing both analgesic and antipyretic properties. Piroxicam exists as alkenol tautomer in organic solvents...
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