Soluble in ethanol, diethyl ether, acetone, benzene
log P
1.16 (23 °C)
Vapor pressure
2 Pa (20 °C)
Acidity (pKa)
0.5 (25 °C, H2O) (conjugate acid)[2]
Dipole moment
2.71
Hazards[5][6]
GHS labelling:
Pictograms
Signal word
Warning
Hazard statements
H302
Precautionary statements
P264, P270, P301+P312, P330, P501
Flash point
174 °C (345 °F; 447 K)
Autoignition temperature
545 °C (1,013 °F; 818 K)
Safety data sheet (SDS)
External MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound
Acetanilide crystals on a watch glass
Acetanilide[7] is an odourless solid chemical of leaf or flake-like appearance. It is also known as N-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name Antifebrin.
^ ab"Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 846. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. N-Phenyl derivatives of primary amides are called 'anilides' and may be named using the term 'anilide' in place of 'amide' in systematic or retained names of amides. (…) However, names expressing N-substitution by a phenyl group on an amide are preferred IUPAC names.
^Haynes, William M., ed. (2016). CRC Handbook of Chemistry and Physics (97th ed.). CRC Press. pp. 5–88. ISBN 9781498754293.
^Weast, Robert C., ed. (1981). CRC Handbook of Chemistry and Physics (62nd ed.). Boca Raton, FL: CRC Press. p. C-67. ISBN 0-8493-0462-8..
^Acetanilide(PDF), SIDS Initial Assessment Report, Geneva: United Nations Environment Programme, September 2003.
^"Safety data for acetanilide". Physical Chemistry Laboratory, University of Oxford. Archived from the original on 2002-06-23..
^"HSNO Chemical Classification Information Database". New Zealand: Environmental Risk Management Authority. Archived from the original on October 13, 2022. Retrieved August 26, 2009.
^Acetanilide, archived from the original on 2007-11-25, retrieved 2007-12-29.
Acetanilide is an odourless solid chemical of leaf or flake-like appearance. It is also known as N-phenylacetamide, acetanil, or acetanilid, and was formerly...
L. A. (1947), "Metabolic fate of acetanilide and other aniline derivatives. II. Major metabolites of acetanilide in the blood", J. Pharmacol. Exp. Ther...
manufactured by Prestige Consumer Healthcare. Its product formerly contained acetanilide, which resulted in a Not Acceptable rating from Consumer Reports .At...
4-Nitroacetanilide is a chemical compound which is a nitro derivative of acetanilide. There are two other isomers of nitroacetanilide, 2-nitroacetanilide...
of acetanilide and phenacetin. In 1947, David Lester and Leon Greenberg found strong evidence that paracetamol was a major metabolite of acetanilide in...
is a substance that increases the rate of a chemical reaction. Added acetanilide slows the decomposition of drug-store hydrogen peroxide solution, inhibiting...
anilides. For example, reaction of aniline with acetyl chloride provides acetanilide (CH3−CO−NH−C6H5). At high temperatures, aniline and carboxylic acids...
organic compounds as possible new medicines, following the success of acetanilide ten years earlier. Two years later, Bayer created acetylsalicylic acid...
aniline are sometimes called anilides, for example CH3−C(=O)−NH−C6H5 is acetanilide. At high temperatures aniline and carboxylic acids react to give the...
Butachlor is a herbicide of the acetanilide class. It is used as a selective pre-emergent herbicide. It is extensively used in India in the form of granules...
gradually gained some acceptance in medical circles. The discovery of acetanilide, in the 1880s, gave rise to an 'acetylation' craze, where chemists experimented...
prefix instead refers to the fact that the drug is chemically related to acetanilide. As of 2021,[update] lidocaine is not listed by the World Anti-Doping...
a more controlled nitration of aniline starts with the formation of acetanilide by reaction with acetic anhydride followed by the actual nitration. Because...
Mehta, S. (25 August 2012). "Metabolism of Paracetamol (Acetaminophen), Acetanilide and Phenacetin | Medicinal Chemistry | PharmaXChange.info". pharmaxchange...
condition known as methemoglobinemia. Axelrod and Brodie discovered that acetanilide, the main ingredient of these pain-killers, was to blame. They found...
Mehta S (25 August 2012). "Metabolism of Paracetamol (Acetaminophen), Acetanilide and Phenacetin". PharmaXChange.info. Archived from the original on 28...
derivatives have analgesic (pain-killer) properties. These included acetanilide, phenacetin, and paracetamol aka acetaminophen. Paracetamol may be the...
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