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Antibody fragment information


An antibody split into Fab and Fc fragments

An antibody fragment can be:

  • a fragment antigen-binding (Fab)
  • a fragment crystallizable (Fc)

and 22 Related for: Antibody fragment information

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Antibody fragment

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An antibody fragment can be: a fragment antigen-binding (Fab) a fragment crystallizable (Fc) This article includes a list of related items that share...

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Fragment crystallizable region

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The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some...

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Antibody

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An antibody (Ab) is the secreted form of a B cell receptor; the term immunoglobulin (Ig) can refer to either the membrane-bound form or the secreted form...

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Recombinant antibodies

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Recombinant antibodies are antibody fragments produced by using recombinant antibody coding genes. They mostly consist of a heavy and light chain of the...

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Monoclonal antibody

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A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent...

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Humanized antibody

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Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants...

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Monoclonal antibody therapy

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Monoclonal antibodies (mAbs) have varied therapeutic uses. It is possible to create a mAb that binds specifically to almost any extracellular target, such...

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Synthetic antibody

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ability to manipulate the antibody genes make it possible to generate new antibodies and antibody fragments, such as Fab fragments and scFv in vitro. This...

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Efgartigimod alfa

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neonatal Fc receptor blocker and is a new class of medication. It is an antibody fragment that binds to the neonatal Fc receptor (FcRn), preventing FcRn from...

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Nomenclature of monoclonal antibodies

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nomenclature of monoclonal antibodies is a naming scheme for assigning generic, or nonproprietary, names to monoclonal antibodies. An antibody is a protein that...

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Bispecific monoclonal antibody

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monoclonal antibodies (MoAbs) came. In 1983, Milstein and Cuello created hybrid-hybridoma (quadroma) technology. In 1988, the single-chain variable fragment (scFv)...

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Digoxin immune fab

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immune fab or digoxin-specific antibody is an antidote for overdose of digoxin. It is made from immunoglobulin fragments from sheep that have already been...

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Antibody mimetic

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not artificial antibodies, antibody fragments and fusion proteins composed from these. Common advantages over antibodies are better solubility, tissue...

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Phage display

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and mRNA display.[citation needed] The invention of antibody phage display revolutionised antibody drug discovery. Initial work was done by laboratories...

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Immunotoxin

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modified antibody or antibody fragment, attached to a fragment of a toxin. The targeting portion is composed of the Fab portion of an antibody that targets...

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Primary and secondary antibodies

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"F(ab')₂ Fragment Secondary Antibodies - Jackson ImmunoResearch". www.jacksonimmuno.com. Retrieved 2021-01-29. "Fab Fragment Secondary Antibodies - Jackson...

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Fc receptor

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specificity for a part of an antibody known as the Fc (fragment crystallizable) region. Fc receptors bind to antibodies that are attached to infected...

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Snake antivenom

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three fragments: two Fab fragments and one Fc fragment. An antibody can also be digested by pepsin to produce two fragments: a F(ab')2 fragment and a...

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ImmTAC

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based targeting system with a single chain antibody fragment (scFv) effector function. TCRs, like antibodies, constitute an important antigen recognition...

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Scab

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during the wound healing reconstruction phase scAb, single-chain antibody fragment Apple scab, an apple tree (genus Malus) fungal disease caused by Venturia...

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Novartis

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(trade name Lucentis), which is a monoclonal antibody fragment derived from the same parent mouse antibody as bevacizumab (Avastin). Both Avastin and Lucentis...

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Antigen

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particulate matter, or an allergen, such as pollen, that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an...

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