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Androgen information


Androgen
Drug class
Testosterone, the major androgen
Class identifiers
SynonymsAndrogenic hormone; Testoid
UseHypogonadism, transgender men, performance enhancement, bodybuilding, others
ATC codeG03B
Biological targetAndrogen receptor, mARs (e.g., GPRC6A, others)
External links
MeSHD000728
Legal status
In Wikidata

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.[1][2] This includes the embryological development of the primary male sex organs, and the development of male secondary sex characteristics at puberty. Androgens are synthesized in the testes, the ovaries, and the adrenal glands.

Androgens increase in both males and females during puberty.[3] The major androgen in males is testosterone.[4] Dihydrotestosterone (DHT) and androstenedione are of equal importance in male development.[4] DHT in utero causes differentiation of the penis, scrotum and prostate. In adulthood, DHT contributes to balding, prostate growth, and sebaceous gland activity.

Although androgens are commonly thought of only as male sex hormones, females also have them, but at lower levels: they function in libido and sexual arousal. Androgens are the precursors to estrogens in both men and women.

In addition to their role as natural hormones, androgens are used as medications; for information on androgens as medications, see the androgen replacement therapy and anabolic steroid articles.

  1. ^ Moini J (2015). Fundamental Pharmacology for Pharmacy Technicians. Cengage Learning. p. 338. ISBN 978-1-30-568615-1. Androgen is the generic term for any natural or synthetic compound, usually a steroid hormone, which stimulates or controls the development of masculine characteristics by binding to androgen receptors.
  2. ^ Gylys BA, Wedding ME (2017). Medical Terminology Systems: A Body Systems Approach. F.A. Davis. p. 82. ISBN 978-0-80-365868-4. Generic term for an agent (usually a hormone, such as testosterone or androsterone) that stimulates development of male characteristics.
  3. ^ "15 Ways To Get Rid of Pimples Overnight Natural". Fast Health Fitness. 17 May 2016.
  4. ^ a b Carlson N (22 January 2012). Physiology of Behavior. Reproductive Behavior. Vol. 11th edition. Pearson. p. 326. ISBN 978-0205239399.

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Complete androgen insensitivity syndrome

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Gynecomastia

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breast tissue as a result of a hormone imbalance between estrogens and androgens. Gynecomastia can cause significant psychological distress or unease....

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Polycystic ovary syndrome

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person has PCOS if they have all of the following: oligoovulation signs of androgen excess (clinical or biochemical) exclusion of other disorders that can...

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Androgen suppression

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Androgen suppression, also known as testosterone suppression, is a medical treatment to suppress or block the production or action of male sex hormones...

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Testosterone

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Testosterone is the primary male sex hormone and androgen in males. In humans, testosterone plays a key role in the development of male reproductive tissues...

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Hyperandrogenism

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Hyperandrogenism is a medical condition characterized by high levels of androgens. It is more common in women than men. Symptoms of hyperandrogenism may...

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Dihydrotestosterone

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5α-dihydrotestosterone, 5α-DHT, androstanolone or stanolone) is an endogenous androgen sex steroid and hormone primarily involved in the growth and repair of...

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Androgen deprivation therapy

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Androgen deprivation therapy (ADT), also called androgen ablation therapy or androgen suppression therapy, is an antihormone therapy whose main use is...

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Androgen backdoor pathway

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The androgen backdoor pathway is responsible for the synthesis of physiologically relevant androgens. This process starts with 21-carbon (C 21) steroids...

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Partial androgen insensitivity syndrome

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Partial androgen insensitivity syndrome (PAIS) is a condition that results in the partial inability of the cell to respond to androgens. It is an X linked...

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Virilization

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males or females. Most of the changes of virilization are produced by androgens. Virilization is a medical term commonly used in three medical and biology...

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List of androgens and anabolic steroids

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This is a list of androgens/anabolic steroids (AAS) or testosterone derivatives. Androgen esters are mostly not included in this list. The major classes...

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Dehydroepiandrosterone

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brain. It functions as a metabolic intermediate in the biosynthesis of the androgen and estrogen sex steroids both in the gonads and in various other tissues...

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Free androgen index

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Free Androgen Index (FAI) is a ratio used to determine abnormal androgen status in humans. The ratio is the total testosterone level divided by the sex...

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Androgen conjugate

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An androgen conjugate is a conjugate of an androgen, such as testosterone. They occur naturally in the body as metabolites of androgens. Androgen conjugates...

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Mild androgen insensitivity syndrome

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Mild androgen insensitivity syndrome (MAIS) is a condition that results in a mild impairment of the cell's ability to respond to androgens. The degree...

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Testosterone enanthate

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Testosterone enanthate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men. It...

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Androgen replacement therapy

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Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often...

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Testosterone cypionate

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cypionate, sold under the brand name Depo-Testosterone among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment...

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Androgen ester

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An androgen or anabolic steroid ester is an ester of an androgen/anabolic steroid (AAS) such as the natural testosterone or dihydrotestosterone (DHT)...

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Cyproterone acetate

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is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty...

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Drostanolone propionate

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under the brand names Drolban, Masteril, and Masteron among others, is an androgen and anabolic steroid (AAS) medication which was used to treat breast cancer...

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