Alpha-cleavage (α-cleavage) in organic chemistry refers to the act of breaking the carbon-carbon bond[1] adjacent to the carbon bearing a specified functional group.[2]
^Hathaway, Bruce A. (2005). Organic chemistry the easy way. Woodbury, N.Y: Barron's Educational Series. p. 315. ISBN 0-7641-2794-2.
^"α-cleavage (alpha-cleavage)". IUPAC Compendium of Chemical Terminology (Gold Book). IUPAC. Archived from the original on 20 July 2008. Retrieved 2008-07-08.
Alpha-cleavage (α-cleavage) in organic chemistry refers to the act of breaking the carbon-carbon bond adjacent to the carbon bearing a specified functional...
follows: Alpha-cleavage can occur on either side of the carbonyl functional group since an oxygen lone pair can stabilize the positive charge. β-cleavage is...
Inductive cleavage, in organic chemistry, is the charge-initiated counterpoint to radical initiated alpha-cleavage. Since inductive cleavage does not require...
processes for organic molecules are the McLafferty rearrangement and alphacleavage. Straight chain alkanes and alkyl groups produce a typical series of...
Alpha hydroxy carboxylic acids, or α-hydroxy carboxylic acids (AHAs), are a group of carboxylic acids featuring a hydroxy group located one carbon atom...
and gamma secretase. The alpha-secretase pathway is the predominant APP processing pathway. Thus, alpha-secretase cleavage precludes amyloid beta formation...
homotrimeric cytokine (sTNF) is released via proteolytic cleavage by the metalloprotease TNF alpha converting enzyme (TACE, also called ADAM17). The soluble...
membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and...
that alpha-sarcin depends on the folded structure of the RNA for recognition and cleavage, but not necessarily the rest of the molecule. The cleavage rate...
Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic...
composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular...
via onium intermediates, i.e. [RO(H)CH3]+Br−. Some ethers undergo rapid cleavage with boron tribromide (even aluminium chloride is used in some cases) to...
the incoming foreign DNA begins a cleavage event (depicted with scissors), which requires Cas proteins. DNA cleavage interferes with viral replication...
fluid-filled bullae. Alpha toxin is a pore-forming toxin exotoxin that is secreted as a protoxin that requires proteolytic cleavage of a 5kDa peptide from...
integral membrane proteins composed of an alpha chain and a beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light...
degradation occurs at wavelengths less than 300 nm. The reaction begins by an alphacleavage between the carbonyl carbon and the oxygen in the carbonate linkage...
Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal growth factor (EGF) family...
methanethiol, which is emitted by paper mills. Demethylation often refers to cleavage of ethers, especially aryl ethers. Historically, aryl methyl ethers, including...
alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. CD49d...
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