Controversy centering on concerns about the biomedical significance of bisphenol A (BPA)
This article needs more reliable medical references for verification or relies too heavily on primary sources. Please review the contents of the article and add the appropriate references if you can. Unsourced or poorly sourced material may be challenged and removed. Find sources: "Health effects of Bisphenol A" – news · newspapers · books · scholar · JSTOR(August 2016)
This article needs attention from an expert in Medicine. The specific problem is: Unfocussed, far too long, few firm conclutions in the lead. WikiProject Medicine may be able to help recruit an expert.(January 2022)
Chemical structure of bisphenol A(BPA).
Bisphenol A controversy centers on concerns and debates about the biomedical significance of bisphenol A (BPA), which is a precursor to polymers that are used in some consumer products, including some food containers. The concerns began with the hypothesis that BPA is an endocrine disruptor, i.e. it mimics endocrine hormones and thus has the unintended and possibly far-reaching effects on people in physical contact with the chemical.
Since 2008, several governments have investigated its safety, which prompted some retailers to withdraw polycarbonate products. The U.S. Food and Drug Administration (FDA) ended its authorization of the use of BPA in baby bottles and infant formula packaging, based on market abandonment, not safety.[1] The European Union and Canada have banned BPA use in baby bottles.
The U.S. FDA states "BPA is safe at the current levels occurring in foods" based on extensive research, including two more studies issued by the agency in early 2014.[2] The European Food Safety Authority (EFSA) reviewed new scientific information on BPA in 2008, 2009, 2010, 2011 and 2015: EFSA's experts concluded on each occasion that they could not identify any new evidence which would lead them to revise their opinion that the known level of exposure to BPA is safe; however, the EFSA does recognize some uncertainties, and will continue to investigate them.[3]
In February 2016, France stated that it intends to propose BPA as a REACH Regulation candidate substance of very high concern (SVHC).[4] The European Chemicals Agency agreed to the proposal in June 2017.[5]
^"FDA Regulations No Longer Authorize the Use of BPA in Infant Formula Packaging Based on Abandonment; Decision Not Based on Safety". Fda.gov. 12 July 2013. Archived from the original on 18 July 2013. Retrieved 1 February 2014.
^"Bisphenol A (BPA): Use in Food Contact Application". FDA. 26 April 2019.
^Cite error: The named reference efsa2015 was invoked but never defined (see the help page).
^"Current SVHC Intentions – Bisphenol A".
^"MSC unanimously agrees that Bisphenol A is an endocrine disruptor". Retrieved 19 November 2017.[permanent dead link]
and 27 Related for: Health effects of Bisphenol A information
BisphenolA controversy centers on concerns and debates about the biomedical significance ofbisphenolA (BPA), which is a precursor to polymers that are...
BisphenolA (BPA) is a chemical compound primarily used in the manufacturing of various plastics. It is a colourless solid which is soluble in most common...
structurally related to bisphenolA (BPA), a popular precursor for forming plastics, as both belong to the category of molecules known as bisphenols, which feature...
The bisphenols (/ˈbɪsfɪnɒl/) are a group of chemical compounds related to diphenylmethane. Most are based on two hydroxyphenyl functional groups linked...
Microplastics effects on human health are a subject of growing concern and an area of research. The tiny particles known as microplastics (MPs), have...
(July 2015). "Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity ofBisphenolA Substitutes". Environmental Health Perspectives...
epoxy resin. Instead ofbisphenolA, other bisphenols (especially bisphenol F) or brominated bisphenols (e. g. tetrabromobisphenol A) can be used for the...
Politics of Plastics: The Making and Unmaking ofBisphenolA 'Safety'" Archived 2017-05-30 at the Wayback Machine. American Journal of Public Health 99 (S3):...
Research indicates that living in areas of high pollution has serious long term healtheffects. Living in these areas during childhood and adolescence...
activity. Bisphenol-A diphenyl phosphate (BADP) and tetrabromobisphenol A (TBBPA) likely degrade to bisphenolA (BPA), an endocrine disruptor of concern...
(2013). "Bisphenol S Disrupts Estradiol-Induced Nongenomic Signaling in a Rat Pituitary Cell Line: Effects on Cell Functions". Environmental Health Perspectives...
2008, Health Canada announced that bisphenolA is "'toxic' to human health". On the same date, Nalgene announced it would phase out production of its Outdoor...
Tetramethyl bisphenol F (TMBPF) is a new coating intended as a safer replacement for bisphenolA and bisphenol F to use in epoxy linings of aluminium cans...
contains a high concentration ofbisphenolA (BPA), an endocrine disruptor. In 2001, three employees ofa medical center in San Francisco filed a lawsuit...
is an endocrine disruptor". The implications for children's health are related to effects during pregnancy and during sexual development, though few studies...
Food Consumption and BisphenolA and Phthalates Exposures among the U.S. Population in NHANES, 2003-2010". Environmental Health Perspectives. 124 (10):...
types of cans may have interior coatings containing chemicals such as BisphenolA (BPA). Reusing containers originally holding paints and other types of chemicals...
produced by the reaction of bromine with bisphenolA. Most commercial TBBPA products consist ofa mixture that differ in the degree of bromination with the...
terms of endocrine-disrupting effects. This has led to criticisms of the chemical industry and for calls to deal with bisphenols in groups, not individually...
exposure to low doses ofbisphenolA affects body weight, patterns of estrous cyclicity, and plasma LH levels". Environmental Health Perspectives. 109 (7):...
sexual maturation, and other healtheffects. Specific phthalates have also resulted in similar biological effects. BisphenolA affects gene expression related...
induces stressed behavior. Alkylphenols like nonylphenol and bisphenolA have estrogenic effects in the body. They are known as xenoestrogens. Estrogenic...
2005). "Urinary concentrations ofbisphenolA and 4-nonylphenol in a human reference population". Environmental Health Perspectives. 113 (4): 391–5. doi:10...
contaminated with the related compound bisphenolA, a potential endocrine disruptor. However, no negative healtheffectsof bis-GMA use in dental resins have...