Alacepril information

Alacepril
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (2S)-2-[[(2S)-1-[(2S)-3-acetylsulfanyl-2-methylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid;
CAS Number	74258-86-9 ;
PubChem CID	71992;
ChemSpider	64993 ;
UNII	X39TL7JDPF;
KEGG	D01900 ;
ChEMBL	ChEMBL2103775 ;
CompTox Dashboard (EPA)	DTXSID3048576 ;
Chemical and physical data
Formula	C20H26N2O5S
Molar mass	406.50 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@H](CSC(=O)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O;
	InChI InChI=1S/C20H26N2O5S/c1-13(12-28-14(2)23)19(25)22-10-6-9-17(22)18(24)21-16(20(26)27)11-15-7-4-3-5-8-15/h3-5,7-8,13,16-17H,6,9-12H2,1-2H3,(H,21,24)(H,26,27)/t13-,16+,17+/m1/s1 ; Key:FHHHOYXPRDYHEZ-COXVUDFISA-N ;
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Alacepril (INN) is an ACE inhibitor medication indicated as a treatment for hypertension. The medication metabolizes to captopril and desacetylalacepril.^[1] Alacepril is primarily used to treat hypertension, and in some cases, renovascular hypertension. It's often combined with other medications, particularly other blood pressure lowering classes of medications like thiazide diuretics to maximize its effectiveness.^[2]

^ "Alacepril". IBM Micromedex. 24 August 2010. Retrieved 23 June 2022.
^ "Alacepril". DrugCentral online drug compendium. Retrieved 13 April 2024. It is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. It used for the treatment of essential or renovascular hypertension (usually administered with other drugs, particularly thiazide diuretics).

[1] "Alacepril". IBM Micromedex. 24 August 2010. Retrieved 23 June 2022.

[2] "Alacepril". DrugCentral online drug compendium. Retrieved 13 April 2024. It is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. It used for the treatment of essential or renovascular hypertension (usually administered with other drugs, particularly thiazide diuretics).

Alacepril information

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Alacepril

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Renin

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Captopril

Olmesartan

Discovery and development of angiotensin receptor blockers

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Angiotensin II receptor blocker

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Angiotensin

Angiotensin II receptor type 1

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (2S)-2-[[(2S)-1-[(2S)-3-acetylsulfanyl-2-methylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
CAS Number	74258-86-9^N
PubChem CID	71992
ChemSpider	64993^Y
UNII	X39TL7JDPF
KEGG	D01900^Y
ChEMBL	ChEMBL2103775^N
CompTox Dashboard (EPA)	DTXSID3048576
Chemical and physical data
Formula	C₂₀H₂₆N₂O₅S
Molar mass	406.50 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[C@H](CSC(=O)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O
InChI InChI=1S/C20H26N2O5S/c1-13(12-28-14(2)23)19(25)22-10-6-9-17(22)18(24)21-16(20(26)27)11-15-7-4-3-5-8-15/h3-5,7-8,13,16-17H,6,9-12H2,1-2H3,(H,21,24)(H,26,27)/t13-,16+,17+/m1/s1^Y Key:FHHHOYXPRDYHEZ-COXVUDFISA-N^Y
^NY (what is this?) (verify)