Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks.[7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus.[7] Lisinopril is taken orally (swallowed by mouth).[7] Full effect may take up to four weeks to occur.[7]
Common side effects include headache, dizziness, feeling tired, cough, nausea, and rash.[7] Serious side effects may include low blood pressure, liver problems, hyperkalemia (high blood potassium), and angioedema.[7] Use is not recommended during the entire duration of pregnancy as it may harm the baby.[7] Lisinopril works by inhibiting the renin–angiotensin–aldosterone system.[7]
Lisinopril was patented in 1978 and approved for medical use in the United States in 1987.[7][11] It is available as a generic medication.[7] In 2021, it was the fourth most commonly prescribed medication in the United States, with more than 88million prescriptions.[12][13] In July 2016, an oral solution formulation of lisinopril was approved for use in the United States.[7][14]
^ abCite error: The named reference Prinivil FDA Label was invoked but never defined (see the help page).
^ ab"Zestril- lisinopril tablet". DailyMed. 31 October 2019. Retrieved 5 August 2020.
^ ab"Qbrelis- lisinopril solution". DailyMed. 31 March 2020. Retrieved 5 August 2020.
^"Dapril". Drugs.com. Drugsite Trust. Retrieved 13 August 2021.
^Cite error: The named reference Brands was invoked but never defined (see the help page).
^ ab"Lisinopril Use During Pregnancy". Drugs.com. 22 October 2019. Retrieved 27 February 2020.
^ abcdefghijkl"Lisinopril Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 23 December 2018.
^"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
^"Product monograph brand safety updates". Health Canada. February 2024. Retrieved 24 March 2024.
^"Summary of Product Characteristics (SmPC) – (emc)". Lisinopril 10mg Tablet. 13 November 2019. Archived from the original on 28 February 2020. Retrieved 27 February 2020.
^Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 467. ISBN 978-3-527-60749-5.
^"The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
^"Lisinopril – Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
^"Drug Approval Package: Qbrelis (lisinopril)". U.S. Food and Drug Administration (FDA). 29 July 2016. Retrieved 5 August 2020.
Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood...
benazepril, zofenopril, perindopril, trandolapril, captopril, enalapril, lisinopril, and ramipril. ACE inhibitors were initially approved for the treatment...
diabetic nephropathy.[citation needed] A 1998 double-blind study found "that lisinopril improved insulin sensitivity whereas losartan did not affect it." Candesartan...
inhibit the actions of angiotensin better than ACE inhibitors, such as lisinopril, because there are other enzymes than ACE that have the capability of...
to angiotensin II in the RAAS pathway. Amlodipine/celecoxib Amlodipine/lisinopril Amlodipine/olmesartan or amlodipine/olmesartan/hydrochlorothiazide if...
citizens with hypertension and diabetes history. About half were receiving Lisinopril (a blood pressure medicine), and many did not remember clearly if they...
secretion or action of aldosterone are in use as antihypertensives, like lisinopril, which lowers blood pressure by blocking the angiotensin-converting enzyme...
inhibitors, captopril is not administered as a prodrug (the only other being lisinopril). About 70% of orally administered captopril is absorbed. Bioavailability...
tablets, but refills are not limited. In August 2011, Publix began offering Lisinopril, an ACE inhibitor that is used to prevent, treat, or improve symptoms...
Hichens, M.; Bolognese, J. A.; Junggren, I. (1989). "Pharmacokinetics of lisinopril (IV/PO) in healthy volunteers". Biopharmaceutics & Drug Disposition. 10...
painkiller Proxyvon (opioid tramadol + paracetamol) and blood pressure drugs (lisinopril, etc.). In 1995, it expanded into biotechnology, and subsequently started...
[medical citation needed] Both captopril and lisinopril are examples of ACE inhibitors. However, lisinopril is dosed once a day, whereas captopril may be...
kidney failure with angiotensin-converting enzyme-inhibitors, such as lisinopril, and diuretics, such as hydrochlorothiazide. A highly selective reversible...
DA, Zhong W, Grandits GA, Cohn JN (June 2013). "Effect of carvedilol, lisinopril and their combination on vascular and cardiac health in patients with...
is the thiazide. Quinapril/hydrochlorothiazide (trade name Accuretic) Lisinopril/hydrochlorothiazide is marketed as Prinzide, Zestoretic, and many others...
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