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Affymetrix is now Applied Biosystems, a brand of DNA microarray products sold by Thermo Fisher Scientific that originated with an American biotechnology research and development and manufacturing company of the same name.[4] The Santa Clara, California-based Affymetrix, Inc. now a part of Thermo Fisher Scientific was co-founded by Alex Zaffaroni and Stephen Fodor. Stephen Fodor and his group, based on their earlier development of methods to fabricate DNA microarrays using semiconductor manufacturing techniques.[5][6]
In 1994, the company's first product under the "GeneChip" Affymetrix trademark, an HIV genotyping chip was introduced,[7] and the company went public in 1996.[8]
After incorporation, Affymetrix grew in part by acquiring technologies from other companies, including Genetic MicroSystems (slide-based Microarrays and scanners)[citation needed] and Neomorphic (for bioinformatics) in 2000,[9] ParAllele Bioscience (custom SNP genotyping),[citation needed] USB/Anatrace (biochemical reagents) in 2008,[10] Panomics (low to mid-plex applications) in 2008,[citation needed] and eBioscience (flow cytometry) in 2012.[11] Affymetrix spun off Perlegen Sciences,[12][when?] as a discrete business focusing on wafer-scale genomics to characterize population-variance of genomic markers.[13]
In January 2014, the Food and Drug Administration approved Affymetrix's postnatal blood test, CytoScan Dx Assay, looking at whole-genome correlates of congenital abnormalities and other causes of childhood developmental delay.[14]
On January 8, 2016, Thermo Fisher Scientific announced its acquisition of Affymetrix for approximately $1.3 billion,[15] which closed on March 31, 2016.[16]
^ abcAffymetrix (AFFX) annual SEC income statement filing via Wikinvest
^ abAffymetrix (AFFX) annual SEC balance sheet filing via Wikinvest
^"Company Profile for Affymetrix Inc (AFFX)". Archived from the original on 2012-03-01. Retrieved 2008-10-20.
^"Thermo Fisher Scientific to acquire Affymetrix". Grainews. Retrieved 2022-03-23.
^"Affymetrix and Illumina Settle Their Patent Disputes". fiercebiotech.com. 10 January 2008. Retrieved 2022-01-12.
^"Stephen Fodor, Jami Nachtsheim". genomeweb.com. 30 January 2015. Retrieved 2022-01-12.
^"Affymetrix and bioMérieux Extend Their Agreement on GeneChip® Technology to Breast Cancer Diagnostics". biomerieux.com. Retrieved 2022-01-12.
^"AFFX Meaning AFFX Stock Meaning". acronym.io. Retrieved 2022-01-12.
^"Affymetrix to Acquire Neomorphic In a Deal Valued at $70 Million". Wall Street Journal. 2 October 2000. Retrieved 2022-01-14.
^"Affymetrix Sells Anatrace Unit to Investment Firm StoneCalibre". genomeweb.com. 15 October 2013. Retrieved 2022-01-28.
^"Affymetrix Completes eBioscience Acquisition". genomeweb.com. 26 June 2012. Retrieved 2022-02-02.
^"Perlegen Signs Its First Big Pharma Deal with GlaxoSmithKline, Finishes Fifty Genomes". genomeweb.com. 27 September 2002. Retrieved 2022-02-02.
^"A Guide to HIV-1 Reverse Transcriptase and Protease Sequencing for Drug Resistance Studies" (PDF). hivdb.stanford.edu. Retrieved 2022-02-09.
^"FDA OKs Postnatal Blood Test for Intellectual Disabilities". medscape.com. Retrieved 2022-02-09.
^Armental, Maria (8 January 2016). "Thermo Fisher Scientific to Buy Affymetrix in $1.3 Billion Cash Deal". The Wall Street Journal. Retrieved 14 January 2016.
^"Thermo Fisher Scientific Completes Acquisition of Affymetrix Following Approval of Transaction by Affymetrix Stockholders". ir.thermofisher.com.
Affymetrix is now Applied Biosystems, a brand of DNA microarray products sold by Thermo Fisher Scientific that originated with an American biotechnology...
providers, including Life Technologies Corporation (2013), Alfa Aesar (2015), Affymetrix (2016), FEI Company (2016), BD Advanced Bioprocessing (2018), and PPD...
protein studies and RNA analysis. USB was acquired by Affymetrix at the start of 2008. "Affymetrix Completes Acquisition Of USB Corporation". www.pharmaceuticalonline...
probes such as the Agilent design) or shorter (25-mer probes produced by Affymetrix) depending on the desired purpose; longer probes are more specific to...
than a million of different probes can be synthesized on an array with Affymetrix's Genechip technology with a detection limit of one to ten copies of mRNA...
Bioconductor software packages focused on the analysis of single channel Affymetrix and two or more channel cDNA/Oligo microarrays. As the project has matured...
at Stanford University. With the establishment of companies, such as Affymetrix, Agilent, Applied Microarrays, Arrayjet, Illumina, and others, the technology...
businessman in the field of DNA microarray technology. He is the co-founder of Affymetrix, a company that produces DNA microarrays to screen gene expression and...
Washington, D.C." She has stated that she worked for Perlegen Sciences and for Affymetrix[when?] "develop[ing] translational research collaborations with academic...
high-density oligonucleotide DNA microarrays data at probe level for Affymetrix GeneChips. In this case, the latent variable corresponds to the RNA concentration...
includes object-oriented data-handling and analysis tools for data from Affymetrix, cDNA microarray, and next-generation high-throughput sequencing methods...
interrogate exons. Initially, Affymetrix created the specification to describe the layout for an Affymetrix GeneChip array. Affymetrix still provides "official"...
children with childhood development disorders. In 2012, Lineagen and Affymetrix, Inc. announced that the companies have signed an agreement where Lineagen...
Most GWAS use products from the two primary genotyping platforms. The Affymetrix platform prints DNA probes on a glass or silicone chip that hybridize...
to perform a complete analysis. Most microarray manufacturers, such as Affymetrix and Agilent, provide commercial data analysis software alongside their...
from DNA microarrays. Integrated Genome Browser was first developed at Affymetrix for their scientists and public sector collaborators to visualize data...
cost per gene and labour saving. Both spotted oligonucleotide arrays and Affymetrix high-density arrays were the method of choice for transcriptional profiling...
analysis, arrays of DNA fragments representing individual exons (e.g. Affymetrix exon microarray) or exon/exon boundaries (e.g. arrays from ExonHit or...
Clevert, D.-A.; Obermayer, K. (2006). "A new summarization method for affymetrix probe level data". Bioinformatics. 22 (8): 943–949. doi:10.1093/bioinformatics/btl033...
Affymetrix microarray chip, but FamilyTreeDNA changed to the Illumina OmniExpress chip and retested all customers who had results from the Affymetrix...
GCOS may refer to: Affymetrix GeneChip Operating Software Global Climate Observing System General Comprehensive Operating System, a family of operating...
co-founded Affymetrix, specializing in using genetics for developing new medicine. He was also involved in the creation of Perlegen Sciences, an Affymetrix spin-off...
Global Information
US$327 Million (FY 2009)[1]
US$-30.6 Million (FY 2009)[1]