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SNP array information


In molecular biology, SNP array is a type of DNA microarray which is used to detect polymorphisms within a population. A single nucleotide polymorphism (SNP), a variation at a single site in DNA, is the most frequent type of variation in the genome. Around 335 million SNPs have been identified in the human genome,[1] 15 million of which are present at frequencies of 1% or higher across different populations worldwide.[2]

  1. ^ "dbSNP Summary". www.ncbi.nlm.nih.gov. Retrieved 4 October 2017.
  2. ^ The 1000 Genomes Project Consortium (2010). "A map of human genome variation from population-scale sequencing". Nature. 467 (7319): 1061–1073. Bibcode:2010Natur.467.1061T. doi:10.1038/nature09534. ISSN 0028-0836. PMC 3042601. PMID 20981092.{{cite journal}}: CS1 maint: numeric names: authors list (link)

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LOH. Copy-neutral LOH cannot be detected by arrayCGH, FISH, or conventional cytogenetics. SNP-based arrays are preferred for virtual karyotyping of tumors...

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oligonucleotide SNP arrays, hundreds of thousands of probes are arrayed on a small chip, allowing for many SNPs to be interrogated simultaneously. Because SNP alleles...

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linkage maps. An SNP array was developed by Song et al., 2013 and has been used for research and breeding; the same team applied their array in Song et al...

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months for stage-3 disease. The median age at diagnosis is 69 years. SNP array karyotyping can detect copy number alterations of prognostic significance...

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hybridization and with high-resolution array-based tests based on array comparative genomic hybridization (or aCGH), SNP array technologies and high resolution...

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results stored in the participant's record; the project may also use SNP array and genomic sequencing methods. Specific genetic data, linked to the individual...

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analyzed with traditional population genetic analyses (microsatellites, SNP-array genotyping, BayeScan (which uses the Dirichlet-multinomial distribution))...

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the RosBREED program for Rosaceae in America. They adapted Axiom's 90k SNP array to a more economical 35k for genomic selection in the program. Molecular...

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homozygous deletion in one sample that was below the resolution of the SNP array. SNP array karyotyping can be used to distinguish, for example, a medulloblastoma...

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higher values of the phenotype y Data from Oligo or cDNA arrays, SNP array, protein arrays, etc. can be utilized in SAM Correlates expression data to...

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Chantot-Bastaraud, Sandra; et al. (2017). "Formation of upd(7)mat by trisomic rescue: SNP array typing provides new insights in chromosomal nondisjunction". Molecular...

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Other techniques are meant to assess a large number of SNPs across the genome, such as SNP arrays. This type of technology is commonly used for genome-wide...

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long-read WGS analysis of 222 individuals. SNP array Genotyping. The project designed ethnic-specific SNP arrays optimized for the Japanese population and...

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sequence all SNPs. That is why GWAS use customizable arrays (SNP chips) to genotype only a subset of the variants identified as tag snps. Most GWAS use...

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present in a tiny number of individuals; by contrast, techniques such as SNP arrays can only detect shared genetic variants that are common to many individuals...

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fresh or paraffin-embedded tumors to assess copy number at these loci. SNP array virtual karyotyping is preferred for tumor samples, including neuroblastomas...

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