Extension of endometrial tissue into the myometrium
Medical condition
Adenomyosis
Adenomyosis uteri seen during laparoscopy: soft and enlarged uterus; the blue spots represent subserous endometriosis.
Specialty
Gynecology
Frequency
20 to 35%.[1]
Adenomyosis is a medical condition characterized by the growth of cells that proliferate on the inside of the uterus (endometrium) atypically located among the cells of the uterine wall (myometrium),[2] as a result, thickening of the uterus occurs. As well as being misplaced in patients with this condition, endometrial tissue is completely functional. The tissue thickens, sheds and bleeds during every menstrual cycle.[2]
The condition is typically found in women between the ages of 35 and 50, but also affects younger women.[3] Patients with adenomyosis often present with painful menses (dysmenorrhea), profuse menses (menorrhagia), or both. Other possible symptoms are pain during sexual intercourse, chronic pelvic pain and irritation of the urinary bladder.
In adenomyosis, basal endometrium penetrates into hyperplastic myometrial fibers. Unlike the functional layer, the basal layer does not undergo typical cyclic changes with the menstrual cycle.[4][5] Adenomyosis may involve the uterus focally, creating an adenomyoma. With diffuse involvement, the uterus becomes bulky and heavier.[6]
Adenomyosis can be found together with endometriosis; it differs in that patients with endometriosis present endometrial-like tissue located entirely outside the uterus. In endometriosis, the tissue is similar to, but not the same as, the endometrium. The two conditions are found together in many cases yet often occur separately.[7][4] Before being recognized as a distinct condition, adenomyosis was called endometriosis interna. The less-commonly-used term adenomyometritis is a more specific name for the condition, specifying involvement of the uterus.[8][9]
^Cite error: The named reference stats was invoked but never defined (see the help page).
^ abR G, C W (2020). "Adenomyosis". StatPearls [Internet]. PMID 30969690.
^Brosens I, Gordts S, Habiba M, Benagiano G (December 2015). "Uterine Cystic Adenomyosis: A Disease of Younger Women". J Pediatr Adolesc Gynecol. 28 (6): 420–6. doi:10.1016/j.jpag.2014.05.008. PMID 26049940.
^Leyendecker, G., Herbertz, M., Kunz, G., Mall, G. (2002). "Endometriosis results from the dislocation of basal endometrium". Hum. Reprod. 17 (10): 2725–2736. doi:10.1093/humrep/17.10.2725. PMID 12351554.
^Cite error: The named reference :0 was invoked but never defined (see the help page).
^Lazzeri L, Di Giovanni A, Exacoustos C, Tosti C, Pinzauti S, Malzoni M, Petraglia F, Zupi E (August 2014). "Preoperative and Postoperative Clinical and Transvaginal Ultrasound Findings of Adenomyosis in Patients With Deep Infiltrating Endometriosis". Reprod Sci. 21 (8): 1027–1033. doi:10.1177/1933719114522520. PMID 24532217. S2CID 24041889.
^"adenomyometritis" at Dorland's Medical Dictionary
^Matalliotakis I, Kourtis A, Panidis D (2003). "Adenomyosis". Obstetrics and Gynecology Clinics of North America. 30 (1): 63–82, viii. doi:10.1016/S0889-8545(02)00053-0. PMID 12699258.
cycle. Adenomyosis may involve the uterus focally, creating an adenomyoma. With diffuse involvement, the uterus becomes bulky and heavier. Adenomyosis can...
muscularis propria. Uterine adenomyoma is the focal form of uterine adenomyosis. Adenomyosis most commonly presents with numerous small collections of endometrial...
Underlying issues that can cause dysmenorrhea include uterine fibroids, adenomyosis, and most commonly, endometriosis. It is more common among those with...
reveals womb condition adenomyosis". BBC News. Retrieved 22 May 2023. I'm in pain because I have something called adenomyosis. You probably haven't heard...
be associated with adenomyosis. "www.calhoun.edu". Archived from the original on 27 July 2011. Retrieved 2010-03-15. "Adenomyosis". Archived from the...
treatment of adenomyosis, which is when the lining of the uterus aberrantly grows into the muscle of the uterus. Symptoms of adenomyosis include heavy...
reproductive-aged women self-report at least one symptom of AUB. As adenomyosis is a common disorder with a prevalence of 20-35% it is often causative...
Painful (i.e. associated with dysmenorrhea): Pelvic inflammatory disease Adenomyosis - extension of the endometrial tissue into the outer muscular wall of...
to learn how to walk again. As a teenager, Harris also suffered from adenomyosis. In 2012, Harris began a relationship with Peter Legler. On the topic...
speculum, and can often be removed with a minor office procedure. Adenomyosis: Adenomyosis is a condition in which endometrial glands are present within the...
Underlying issues that can cause dysmenorrhea include uterine fibroids, adenomyosis, and most commonly, endometriosis. It is more common among those with...
myometrium is known as the junctional zone, which becomes thickened in adenomyosis. The perimetrium is a serous layer of visceral peritoneum. It covers...
is abnormally high. It can be a symptom of medical conditions such as adenomyosis, uterine fibroids, ovarian cysts, and endometrial cancer. Uterine hypoplasia...
treat some benign tumors, cancers of the ovaries, uterus or cervix, Adenomyosis but not endometriosis and are also performed in trans men. Making the...
with chronic pelvic pain, a symptom common to other disorders including adenomyosis, pelvic adhesions, pelvic inflammatory disease, congenital anomalies...
important only in so far as it should not be misdiagnosed as cancer. Adenomyosis is the growth of the endometrium into the muscle layer of the uterus...
cavity. This inappropriate tissue growth can lead to pain and bleeding. Adenomyosis: a form of endometriosis, where the uterine lining has grown into and...
Pelvic inflammatory disease—pain caused by damage from infections. Adenomyosis. Adenomyosis is a medical condition characterized by the growth of cells that...
treatment of: Heavy menstrual periods Endometriosis and chronic pelvic pain Adenomyosis and dysmenorrhea Anemia Endometrial hyperplasia (especially in pre-menopausal...
used to remove part of the uterine wall in women with menstruation and adenomyosis problems in a process called endometrial ablation. Recently, researchers...
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