Zalcitabine (2′-3′-dideoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse-transcriptase inhibitor (NRTI) sold under the trade name Hivid. Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration (FDA) for the treatment of HIV/AIDS. It is used as part of a combination regimen.
Zalcitabine appears less potent than some other nucleoside RTIs, has an inconvenient three-times daily frequency and is associated with serious adverse events. For these reasons it is now rarely used to treat human immunodeficiency virus (HIV), and it has even been removed from pharmacies entirely in some countries.[1]
Zalcitabine (2′-3′-dideoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse-transcriptase inhibitor (NRTI) sold under the trade...
Diesel Corporation Dewey Decimal Classification Dideoxycytidine or ddC or zalcitabine Direct digital control, reading and steering of HVAC devices District...
A. Herceptin (trastuzumab), for HER-2 positive breast cancer. Hivid (zalcitabine), for HIV-1 infection, later discontinued in 2006. Inhibace (cilazapril)...
pyrimidine CCR5 entry inhibitor Vidarabine Herpes Simplex, Varicella Zoster Zalcitabine HIV Zanamivir (Relenza) Influenza A, Influenza B Zidovudine HIV Antiretroviral...
antacids can increase pH and inhibit the absorption of other drugs such as zalcitabine, tipranavir and amprenavir. The opposite is more common, with, for example...
for cancer. Horwitz was also first to synthesize stavudine (d4T) and zalcitabine (ddC) - two other reverse-transcriptase inhibitors used in the treatment...
agent. Administration with drugs with overlapping toxicity, such as zalcitabine and stavudine, is not recommended. Alcohol can exacerbate didanosine's...
(AZT) as well as other anti-AIDS drugs including didanosine (ddI) and zalcitabine (ddC). Mitsuya was born in Sasebo, Nagasaki and received his M.D. and...
acid produces optically pure 5-hydroxymethyldihydrofuranone, from which zalcitabine, formerly a HIV drug, is available. In a two-step hydrogenation process...
AIDS epidemic, he co-developed zidovudine (AZT), didanosine (ddI), and zalcitabine (ddC), which were the first effective drugs licensed for the treatment...
for the treatment of AIDS and HIV infection, Zidovudine; synthesized Zalcitabine (ddC) and Stavudine (d4T), the third and fourth drugs approved to treat...
It also transports the anti-viral nucleoside analogues Zidovudine and Zalcitabine. Che M, Ortiz DF, Arias IM (Jun 1995). "Primary structure and functional...
Integral involvement in new antiretroviral drug development: Zidovudine, Zalcitabine, Didanosine, Stavudine, nevirapine, delavirdine, indinavir, amprenavir...
Global Information
