48,XXY Y Klinefelter syndrome (archaic); 48,XXYY variant of Klinefelter's syndrome (archaic)[1]
XXYY syndrome
XXYY syndrome is a sex chromosome anomaly in which males have 2 extra chromosomes, one X and one Y chromosome. Human cells usually contain two sex chromosomes, one from the mother and one from the father. Usually, females have two X chromosomes (XX) and males have one X and one Y chromosome (XY). The appearance of at least one Y chromosome with a properly functioning SRY gene makes a male. Therefore, humans with XXYY are genotypically male. Males with XXYY syndrome have 48 chromosomes instead of the typical 46. This is why XXYY syndrome is sometimes written as 48, XXYY syndrome or 48, XXYY. It affects an estimated one in every 18,000–40,000 male births.[2]
^"48,XXYY syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Archived from the original on 13 January 2020. Retrieved 19 May 2019.
^Cite error: The named reference pmid18481271 was invoked but never defined (see the help page).
XXYYsyndrome is a sex chromosome anomaly in which males have 2 extra chromosomes, one X and one Y chromosome. Human cells usually contain two sex chromosomes...
others. Those with XXXY syndrome tend to display less externalizing and internalizing behaviors compared to those with 48,XXYYsyndrome, which may have a positive...
problems are typical. One study looked at males that were diagnosed with 48,XXYY, 48,XXXY and 49,XXXXY. They found that males with 48,XXXY and 49,XXXXY function...
extra Y chromosome. Klinefelter syndromeXXYYsyndrome XYYY syndrome XYYYY syndrome Turner syndrome Trisomy X "47,XYY syndrome". Genetics Home Reference. January...
Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome...
gametes. XXXYY syndrome, by its nature, requires multiple steps of nondisjunction. Possible causes include fertilization of a normal egg by an XXYY sperm, fertilization...
Turner syndrome (TS), also known as 45,X, or 45,X0, is a genetic disorder in which a person's cells have only one X chromosome or are partially missing...
known as seasonal mood swings. XXYYsyndrome: XXYYsyndrome is a rare type of sex chromosome aneuploidies (SCAs). XXYYsyndrome contributes to abnormal neurodevelopment...
discovered, being preceded by Turner, Klinefelter, and trisomy X in 1959, XXYYsyndrome in 1960, and XYY and tetrasomy X in 1961. By the time of Linden, Bender...
Intersex Taurodontism Trisomy X Turner syndrome XYY syndromeXXYYsyndrome "What are common symptoms of Klinefelter syndrome (KS)?". Eunice Kennedy Shriver National...
Turner's syndrome - a single X chromosome is present, Klinefelter's syndrome - two X chromosomes and a Y chromosome are present, XYY syndrome and XXYY syndrome...
as limb anomalies, syndromes involving multiple systems, and Down syndrome. Recent studies have concluded that 5-9% of Down syndrome cases are due to paternal...
is present Pallister-Killian syndrome (tetrasomy 12p) Tetrasomy 9p Tetrasomy 18p Tetrasomy 21, a rare form of Down syndrome Tetrasomy X XXYYsyndrome...
only one chromosome) except in cases of aneuploidy such as XYY syndrome or XXYYsyndrome. Traits that are inherited via the Y chromosome are called Y-linked...
risk of miscarriage, including diabetes, endometriosis, polycystic ovary syndrome (PCOS), hypothyroidism, certain infectious diseases, and autoimmune diseases...
other X polysomies (48,XXXX, 48,XXXY, 48,XXYY) is more rare than 49,XXXXY. Polysomy Y (47,XYY; 48,XYYY; 48,XXYY; 49,XXYYY) occurs in 1 out of 975 males...
Klinefelter syndrome is in general in the normal range, although below average. When additional X and/or Y chromosomes are present in 48,XXXY, 48,XXYY, or 49...
chromosomes (48,XXXY; 48,XXYY; 49,XXXXY), mosaicism (46,XY/47,XXY), or structural chromosome abnormalities. The incidence of XYY syndrome is approximately 1...
found in Down syndrome, affecting 1 in 800 births. Trisomy 18 (Edwards syndrome) affects 1 in 6,000 births, and trisomy 13 (Patau syndrome) affects 1 in...
D'Epagnier C, Zeitler P (June 2011). "48,XXYY, 48,XXXY and 49,XXXXY syndromes: not just variants of Klinefelter syndrome". Acta Paediatrica. 100 (6): 851–860...
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