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Whey acidic protein information


WAP
R-elafin, a specific inhibitor of elastase
(11 NMR structures, PDB: 2REL​)
Identifiers
SymbolWAP
PfamPF00095
Pfam clanCL0454
InterProIPR008197
PROSITEPDOC00026
SCOP21fle / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

In molecular biology, the Whey acidic proteins (WAP) have been identified as a major whey protein family in milk, and are important in regulating the proliferation of mammary epithelial cells. Additionally, their physiological function is thought to be similar to a protease inhibitor. It has been concluded, therefore, that WAP regulate the proliferation of mammary epithelial cells by preventing elastase-type serine proteases from carrying out laminin degradation and by suppressing the MAP kinase signal pathway in the cell cycle.[1]

  1. ^ Seki M, Matsura R, Iwamori T, Nukumi N, Yamanouchi K, Kano K, et al. (2012). "Identification of whey acidic protein (WAP) in dog milk". Exp Anim. 61 (1): 67–70. doi:10.1538/expanim.61.67. PMID 22293674.

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Whey acidic protein

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In molecular biology, the Whey acidic proteins (WAP) have been identified as a major whey protein family in milk, and are important in regulating the...

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Whey protein

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Whey protein is a mixture of proteins isolated from whey, the liquid material created as a by-product of cheese production. The proteins consist of α-lactalbumin...

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Whey

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several minor whey proteins. Sweet whey and acid whey are similar in gross nutritional analysis. By mass both contain 93% water, about 0.8% protein, and about...

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Whey cheese

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primarily made of coagulated milk proteins, they are technically not cheese. Lactose content is high. Cheese and whey cheese are distinct categories in...

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Protein digestibility corrected amino acid score

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Protein digestibility-corrected amino acid score (PDCAAS) is a method of evaluating the quality of a protein based on both the amino acid requirements...

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Ricotta

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 'recooked' or 'refined') protein can be harvested if the whey is first allowed to become more acidic by additional fermentation (by letting it sit for 12–24...

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Protein quality

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-- Whey, acid, fluid". Ndb.nal.usda.gov. Archived from the original on June 25, 2016. Retrieved 9 November 2017. "Recent developments in protein quality...

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Curd

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The remaining liquid, which contains only whey proteins, is the whey. In cow's milk, 90 percent of the proteins are caseins. Curds can be used in baking...

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Pea protein

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protein (curd) is separated from the supernatant (whey) by filtration or centrifugation. The curd must be washed in order to remove residues of whey solubles...

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Rice protein

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Rice protein is a vegan protein isolate made from rice. It is often used as an alternative to the more common whey and soy protein isolates. To make it...

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Hydrolyzed protein

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De; Wilson, Jacob (September 21, 2015). "The effects of beef protein isolate and whey protein isolate supplementation on lean mass and strength in resistance...

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Bodybuilding supplement

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high protein drinks, pre-workout blends, branched-chain amino acids (BCAA), glutamine, arginine, essential fatty acids, creatine, HMB, whey protein, ZMA...

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Protein supplement

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available as a protein shake. Usually made from whey, plant, and/or meat sources. Protein supplements are extracts or concentrates of high protein foodstuffs...

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WFDC5

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Ranganathan S, Simpson KJ, Shaw DC, Nicholas KR (Mar 2000). "The whey acidic protein family: a new signature motif and three-dimensional structure by...

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Trappin protein transglutaminase binding domain

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biology, the trappin protein transglutaminase binding domain or cementoin is a protein domain found at the N-terminus of Whey Acidic Protein (WAP) domain-containing...

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Glycomacropeptide

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similar amounts in whey. Together GMP and CMP make up 20-25% of whey protein. This makes them the third largest fraction of whey protein isolate, after alpha-lactalbumin...

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Sour cream

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denatured β-lactoglobulin. The adsorption of the denatured whey proteins (and whey proteins that bound with casein micelles) increases the number of structural...

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Butter

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the top, whey proteins form a skin, which is removed. The resulting butterfat is then poured off from the mixture of water and casein proteins that settle...

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List of foods by protein content

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supplements): Soy protein isolate (prepared with sodium or potassium): 80.66 Whey protein isolate: 79 Egg white, dried: 81.1 Spirulina alga, dried: 57.45 (more...

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Soy protein

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drying Soy protein concentrate is produced by immobilizing the soy globulin proteins while allowing the soluble carbohydrates, soy whey proteins, and salts...

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Cheese

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82 °C (180 °F). Acid-set cheeses, including halloumi, paneer, some whey cheeses and many varieties of fresh goat cheese, have a protein structure that...

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Metabolic window

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2014). "Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance...

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Lactic acid

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3CH(OH)CO− 2. Compared to acetic acid, its pKa is 1 unit less, meaning lactic acid is ten times more acidic than acetic acid. This higher acidity is the consequence...

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Strained yogurt

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straining yogurt is called "acid whey" and is composed of water, yogurt cultures, protein, a slight amount of lactose, and lactic acid. It is costly to dispose...

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Biological value

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protein is only 93.7% which allows other proteins with true percentage BV between 93.7% and 100% to take a relative BV of over 100. For example, whey...

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Ziger

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hard Swiss-type cheeses, such as Gruyère and Emmental. Made of whey, it is rich in proteins and it is historically a staple food in the Alpine regions. The...

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Rivella

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Barth in 1952, which is produced from milk whey, and therefore includes ingredients such as lactose, lactic acid and minerals. Other than Switzerland, it...

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