WD Repeat and Coiled-coiled containing protein (WDCP) is a protein which in humans is encoded by the WDCP gene. The function of the protein is not completely understood, but WDCP has been identified in a fusion protein with anaplastic lymphoma kinase found in colorectal cancer.[5] WDCP has also been identified in the MRN complex, which processes double-stranded breaks in DNA.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000163026 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000051721 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Yakirevich E, Resnick MB, Mangray S, Wheeler M, Jackson CL, Lombardo KA, et al. (August 2016). "Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target". Clinical Cancer Research. 22 (15): 3831–40. doi:10.1158/1078-0432.ccr-15-3000. PMID 26933125.
^"WDCP Gene". GeneCards. GeneCards Suite. Retrieved 28 April 2020.
and 24 Related for: WD Repeat and Coiled Coil Containing Protein information
WDRepeatandCoiled-coiledcontainingprotein (WDCP) is a protein which in humans is encoded by the WDCP gene. The function of the protein is not completely...
consists of 60-70 amino acids andcontains heptad repeats that have the ability to form coiled-coil structures. V- and t-SNAREs are capable of reversible...
alpha-helical domain used by two monomers to coil around each other, forming a dimer structure called a coiledcoil. Two of these dimer structures then join...
modules or as multiple tandem repeatscontaining two domains. Both of these possibilities can occur in a single protein in a variety of different conformations...
chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction...
near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as...
domains with no C-terminal coiledcoil region. N-terminus signature region is reduced to 5aa and appears in front of each WD-repeat core domain (e.g., CRN7...
VPS39: encoding protein hVam6p/Vps39-like protein WDR76: encoding proteinWdrepeat domain 76 ZNF592: encoding protein Zinc finger protein 592 The following...
stress granules are biomolecular condensates in the cytosol composed of proteinsand RNAs that assemble into 0.1–2 μm membraneless organelles when the cell...
DUF1220 domains. NBPF1 contains three coiledcoil domains and nine DUF1220 domains in humans. The coiledcoil domains are 60-100 amino acids long, while...
region (coiled-coil domain, CCD), and a domain made of seven WD40 repeats, that forms a β-propeller, found in its C-terminal part. Polymorphisms and mutations...
residues present in both proteins. Actin was first observed experimentally in 1887 by W.D. Halliburton, who extracted a protein from muscle that 'coagulated'...
Cytohesin-1 formerly known as Pleckstrin homology, Sec7 andcoiled/coil domains 1 (PSCD1) is a protein that in humans is encoded by the CYTH1 gene. Cytohesin-1...
Jeon AH, Hwang SG, Chun JS, Lee CW (September 2004). "WDrepeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase"...
nucleotides, and genes exist as stretches of sequence along the DNA chain. These chains coil into a double a-helix structure and wrap around proteins called...
Dreyfuss G (February 2002). "Gemin5, a novel WDrepeatprotein component of the SMN complex that binds Sm proteins". The Journal of Biological Chemistry. 277...
being shaped like spindles or lemons, rods, bottles, droplets, andcoils. Some contain a viral envelope, a lipid membrane that surrounds the viral capsid...
chromosome 9 and is 198 amino acids long. The C9orf25 and FAM219B genes duplicated and diverged between 684 and 797 million years ago. The C9orf25 protein is composed...
nucleoid contains the chromosome with its associated proteinsand RNA. Like all other organisms, bacteria contain ribosomes for the production of proteins, but...
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