Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C5H4N4O3. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. High blood concentrations of uric acid can lead to gout and are associated with other medical conditions, including diabetes and the formation of ammonium acid urate kidney stones.
Uricacid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C5H4N4O3. It forms ions and salts known as urates and...
and swollen joint, caused by the deposition of needle-like crystals of uricacid known as monosodium urate crystals. Pain typically comes on rapidly, reaching...
uricacid. Serum uricacid level at or below 6 mg/100 mL is often a therapeutic goal. Hyperuricemia is not necessary for the formation of uricacid stones;...
high level of uricacid in the blood. In the pH conditions of body fluid, uricacid exists largely as urate, the ion form. Serum uricacid concentrations...
Acute uricacid nephropathy (AUAN, also acute urate nephropathy) is a rapidly worsening (decreasing) kidney function (acute kidney injury) that is caused...
which is then converted to uricacid. Oxygen is the final electron acceptor in the degradation of both purines. Uricacid is then excreted from the body...
livers have trouble breaking down uricacid, which can build up in the blood serum (hyperuricemia) causing gout. Uricacid can also be excreted in high concentration...
a key), because Baeyer had regarded barbituric acid as central (or "key") to understanding uricacid and its derivatives. However, Fieser subsequently...
hyperuricemia (high blood levels of uricacid), pain in arms or legs, and anemia (low red blood cell counts). Bempedoic acid blocks an enzyme in the liver called...
glyoxylic acid. Allantoin is a major metabolic intermediate in most organisms including animals, plants and bacteria. It is produced from uricacid, which...
from allantoin, a product of uricacid excreted by the fetus into the allantois, and oxaluric acid derived from oxalic acid and urea, found in urine. Alloxan...
that helps to clear uricacid from the blood. It is a recombinant version of urate oxidase, an enzyme that metabolizes uricacid to allantoin. Urate oxidase...
phosphate (hyperphosphatemia), low blood calcium (hypocalcemia), high blood uricacid (hyperuricemia), and higher than normal levels of blood urea nitrogen...
produce waste products such as carbon dioxide, water, salts, urea and uricacid. Accumulation of these wastes beyond a level inside the body is harmful...
Hyperuricosuria is a medical term referring to the presence of excessive amounts of uricacid in the urine. For men this is at a rate greater than 800 mg/day, and for...
the reaction sequence was uricacid (8), which had been isolated from kidney stones by Carl Wilhelm Scheele in 1776. Uricacid (8) was reacted with PCl5...
substances that increase the excretion of uricacid in the urine, thus reducing the concentration of uricacid in blood plasma. In general, this effect...
xanthine and finally to uricacid. Instead of uricacid secretion, guanine and IMP can be used for recycling purposes and nucleic acid synthesis in the presence...
of uricacid in the body increases, so does the concentration of uricacid in the joint liquid and beyond a critical concentration, the uricacid begins...
determine whether the body is producing too much uricacid or the body isn't excreting enough uricacid. Rheumatoid factor may be present, especially in...
effect of the buildup of protein metabolic waste compounds, like urea, uricacid, ammonia, and creatinine. Protein toxicity has many causes, including...
monosodium urate crystals, in people with longstanding high levels of uricacid (urate) in the blood, a condition known as hyperuricemia. Tophi are pathognomonic...
Bacillus fastidiosus is only able to grow in the presence of uricacid, allantoin, or allantoic acid. This species has been recently transferred into the genus...
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