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Uniparental inheritance information


Uniparental inheritance is a non-Mendelian form of inheritance that consists of the transmission of genotypes from one parental type to all progeny. That is, all the genes in offspring will originate from only the mother or only the father. This phenomenon is most commonly observed in eukaryotic organelles such as mitochondria and chloroplasts. This is because such organelles contain their own DNA and are capable of independent mitotic replication that does not endure crossing over with the DNA from another parental type. Although uniparental inheritance is the most common form of inheritance in organelles, there is increased evidence of diversity. Some studies found doubly uniparental inheritance (DUI) and biparental transmission to exist in cells. Evidence suggests that even when there is biparental inheritance, crossing-over doesn't always occur. Furthermore, there is evidence that the form of organelle inheritance varied frequently over time. Uniparental inheritance can be divided into multiple subtypes based on the pathway of inheritance.[1][2]

  1. ^ Xu, Jianping (1 December 2005). "The inheritance of organelle genes and genomes: patterns and mechanisms". Genome. 48 (6): 951–958. doi:10.1139/g05-082. PMID 16391664.
  2. ^ Birky, C. W. (5 December 1995). "Uniparental inheritance of mitochondrial and chloroplast genes: mechanisms and evolution". Proceedings of the National Academy of Sciences. 92 (25): 11331–11338. Bibcode:1995PNAS...9211331B. doi:10.1073/pnas.92.25.11331. PMC 40394. PMID 8524780.

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Uniparental inheritance

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Uniparental inheritance is a non-Mendelian form of inheritance that consists of the transmission of genotypes from one parental type to all progeny. That...

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Extranuclear inheritance

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maternally, but paternal inheritance in many species is increasingly being identified. The mechanisms of uniparental inheritance from species to species...

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Uniparental disomy

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Uniparental inheritance of imprinted genes can also result in phenotypical anomalies. Although few imprinted genes have been identified, uniparental inheritance...

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Heteroplasmy

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combination of alleles from both parents, making inheritance biparental. Conversely, organelle inheritance is uniparental, meaning the genes are all inherited from...

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Mitochondrial DNA

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egg. Whatever the mechanism, this single parent (uniparental inheritance) pattern of mtDNA inheritance is found in most animals, most plants and also in...

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Heredity

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cell. Hard inheritance Lamarckism Heritability Particulate inheritance Non-Mendelian inheritance Extranuclear inheritance Uniparental inheritance Epigenetic...

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Mitochondrion

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paternal inheritance only occurs within males of the species. It has been suggested that it occurs at a very low level in humans. Uniparental inheritance leads...

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Meretrix lamarckii

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Veneridae. It is the second species of venerid clam where doubly uniparental inheritance (DUI) has been identified. It is a medium-sized clam which lives...

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Extrachromosomal DNA

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the mother. This uniparental inheritance is an example of non-Mendelian inheritance. Plants also show uniparental mtDNA inheritance. Most plants inherit...

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Paternal mtDNA transmission

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mussels, Mytilus edulis: implications for the mechanism of doubly uniparental inheritance of mitochondrial DNA". Genetics. 148 (1): 341–7. doi:10.1093/genetics/148...

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Chloroplast

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doi:10.3732/ajb.94.1.42. PMID 21642206. Birky CW (December 1995). "Uniparental inheritance of mitochondrial and chloroplast genes: mechanisms and evolution"...

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Mitochondrial Eve

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77.11.6715. PMC 350359. PMID 6256757. Birky CW (August 2008). "Uniparental inheritance of organelle genes". Current Biology. 18 (16): R692–R695. doi:10...

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Unionidae

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mitochondria also may be responsible for the evolution of doubly uniparental inheritance seen in freshwater mussels. The following classification is based...

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Genetic marker

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genealogy to determine genetic distance between individuals or populations. Uniparental markers (on mitochondrial or Y chromosomal DNA) are studied for assessing...

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Selfish genetic element

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mitochondria, creating a situation for competition over transmission. Uniparental inheritance has been suggested to be a way to reduce the opportunity for selfish...

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Eukaryote hybrid genome

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heightened conflict on sex chromosomes. Findings of selection for uniparental inheritance of e.g. mitonuclear loci residing on the Z chromosome in hybrid...

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Ursula Goodenough

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development. These include genes responsible for mate recognition, uniparental inheritance of chloroplast DNA, and gametic differentiation, allowing analysis...

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Genetic disorder

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generations in several ways. Genomic imprinting and uniparental disomy, however, may affect inheritance patterns. The divisions between recessive and dominant...

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Epigenetics of human development

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occur naturally in mammals. In most animals, especially mammals, uniparental inheritance of chromosomes is often lethal or results in developmental abnormalities...

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Nondisjunction

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the remaining cases by post-zygotic, i.e., mitotic, nondisjunction. Uniparental disomy denotes the situation where both chromosomes of a chromosome pair...

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Human mitochondrial DNA haplogroup

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HIP: Haplogroup trees. HIP Haplomap: Ancient uniparental map. AH DNA: Nicky Rosenblatt's ancient uniparental map. Ancient DNA: An aDNA map made with Map...

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Ruth Sager

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their parents. This research provided evidence for non-Mendelian uniparental inheritance; it also showed that there are multiple independent genetic systems...

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Polysomy

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individuals possess three copies (trisomy) of chromosome 21. Polysomic inheritance occurs during meiosis when chiasmata form between more than two homologous...

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Consanguinity

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the same gene. Except in certain rare circumstances (new mutations or uniparental disomy) both parents of an individual with such a disorder will be carriers...

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Angelman syndrome

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Occasionally it is due to the inheritance of two copies of chromosome 15 from the father and none from the mother (paternal uniparental disomy). As the father's...

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Genetic studies on Arabs

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and then by blood, immune disorders and then neoplasms. The Mode of Inheritance is mainly autosomal recessive followed by autosomal dominant. Some of...

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