Tumor initiation is defined as "a process in which normal cells are changed so that they are able to form tumors".[1] It is the first phase in tumor development.[2] Mutagens, substances that cause cancer can be tumor initiators.
^"tumor initiation". National Cancer Institute. Retrieved 9 Nov 2012.
^Compton C (2020). "Cancer initiation, promotion, and progression and the acquisition of key behavioral traits.". Cancer: The Enemy from Within. Cham: Springer. pp. 25–48. doi:10.1007/978-3-030-40651-6_2.
Tumorinitiation is defined as "a process in which normal cells are changed so that they are able to form tumors". It is the first phase in tumor development...
unknown primary origin. Neoplastic tumors are often heterogeneous and contain more than one type of cell, but their initiation and continued growth are usually...
of c-jun can largely suppress tumor formation. Also, c-jun is required for tumor cell survival between the initiation and progression stages. In contrast...
nuclear polymorphism.[citation needed] TumorinitiationTumor promotion Compton C (2020). "Cancer initiation, promotion, and progression and the acquisition...
VEGF, or Akt. Phorbol myristate acetate TumorinitiationTumor progression Compton C (2020). "Cancer initiation, promotion, and progression and the acquisition...
from tumor cells. Stromal cells contribute to tumorinitiation, progression and drug resistance, and the stroma is known to evolve as the tumor develops...
A benign tumor is a mass of cells (tumor) that does not invade neighboring tissue or metastasize (spread throughout the body). Compared to malignant (cancerous)...
Prebys: Insights into the complex system of networks and mechanisms that tumors use to survive and proliferate. Findings build dialogue with clinicians...
changes in the local microenvironment on neoplastic evolution from tumorinitiation to death. Epigenetic alterations are much more frequent in colon cancer...
STAT5b, IGF-1R and VEGF, confirming the ability of MSM to suppress tumorinitiation, growth and metastasis in a dose dependent manner. The expression of...
study illustrated a 69% correlation between NJDS gene mutation and the tumorinitiation.[citation needed] A single case report has linked oligodendroglioma...
binding and scanning. In cancerous cells, initiation factors assist in cellular transformation and development of tumors. The survival and growth of cancer is...
driver events per tumor, of which 0.6 are point mutations in oncogenes, 1.5 are amplifications of oncogenes, 1.2 are point mutations in tumor suppressors,...
White, J. G.; Keely, P. J. (2008). "Collagen density promotes mammary tumorinitiation and progression". BMC Medicine. 6: 11. doi:10.1186/1741-7015-6-11....
cancer, head and neck cancer, soft tissue sarcomas and bladder cancer. Tumorinitiation and progression are influenced by age, nutrition, sex, reproduction...
Tumor necrosis factor (TNF, cachexin, or cachectin; formerly known as tumor necrosis factor alpha or TNF-α) is a cytokine and member of the TNF superfamily...
the presence of encephalitis and poor prognosis. LDH is involved in tumorinitiation and metabolism. Cancer cells rely on increased glycolysis resulting...
invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal...
survival, and the presence of cancer stem cells, which contribute to tumorinitiation and progression. Vismodegib FDA approved (Jan 2012) for basal cell...
Elena; Brown, Jay; et al. (2011). "The roles of viruses in brain tumorinitiation and oncomodulation". Journal of Neuro-Oncology. 105 (3): 451–66. doi:10...
a subset of tumor cells known as breast cancer stem cells (BCSCs). These cells possess the abilities of self-renewal and tumorinitiation, allowing them...
skin cancer which targeted the activator proteins associated with tumorinitiation. Gingerol compounds inhibited the transformation of normal cells into...
Phyllodes tumors (from Greek: phullon), are a rare type of biphasic fibroepithelial mass that form from the periductal stromal and epithelial cells of...