Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound
Gingerol
Heat
Very hot (chemical)
Scoville scale
60,000 SHU
Gingerol ([6]-gingerol) is a phenolic phytochemical compound found in fresh ginger that activates heat receptors on the tongue.[1][2] It is normally found as a pungent yellow oil in the ginger rhizome, but can also form a low-melting crystalline solid. This chemical compound is found in all members of the Zingiberaceae family and is high in concentrations in the grains of paradise as well as an African Ginger species.
Cooking ginger transforms gingerol via a reverse aldol reaction into zingerone, which is less pungent and has a spicy-sweet aroma. When ginger is dried or mildly heated, gingerol undergoes a dehydration reaction forming shogaols, which are about twice as pungent as gingerol.[3] This explains why dried ginger is more pungent than fresh ginger.[4]
Ginger also contains [8]-gingerol, [10]-gingerol,[5] and [12]-gingerol,[6] collectively deemed gingerols.
^Mao QQ, Xu XY, Cao SY, Gan RY, Corke H, Beta T, Li HB (May 2019). "Zingiber officinale Roscoe)". Foods. 8 (6): 185. doi:10.3390/foods8060185. PMC 6616534. PMID 31151279.
^Yin, et al. (17 June 2019). "Structural mechanisms underlying activation of TRPV1 channels by pungent compounds in gingers". British Journal of Pharmacology. 176 (17): 3364–3377. doi:10.1111/bph.14766. PMC 6692589. PMID 31207668.
^NSF International Determination of Gingerols and Shogaols in Zingiber officinale rhizome and powdered extract by High-Performance Liquid Chromatography[full citation needed]
^McGee, Harold (2004). "A survey of tropical spices". McGee on Food and Cooking. Hodder and Stoughton. p. 426. ISBN 0-340-83149-9.
^Zick SM, Djuric Z, Ruffin MT, Litzinger AJ, Normolle DP, Alrawi S, et al. (August 2008). "Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects". Cancer Epidemiology, Biomarkers & Prevention. 17 (8): 1930–6. doi:10.1158/1055-9965.EPI-07-2934. PMC 2676573. PMID 18708382.
^Park M, Bae J, Lee DS (November 2008). "Antibacterial activity of [10]-gingerol and [12]-gingerol isolated from ginger rhizome against periodontal bacteria". Phytotherapy Research. 22 (11): 1446–9. doi:10.1002/ptr.2473. PMID 18814211. S2CID 31384218.
Gingerol ([6]-gingerol) is a phenolic phytochemical compound found in fresh ginger that activates heat receptors on the tongue. It is normally found as...
gingerol. The most common of the group is [6]-shogaol. Like zingerone, it is produced when ginger is dried or cooked. Moreover, shogaol (and gingerol)...
Korbua (2016-10-31). "Electrochemical detection and quantification of gingerol species in ginger (Zingiber officinale) using multiwalled carbon nanotube...
The modern practice commonly involves a paste product with concentrated gingerol. For the halter horses in the Arabian and American Saddlebred breeds, high...
2022). "Development of Cyclodextrin-Functionalized Transethoniosomes of 6-Gingerol: Statistical Optimization, In Vitro Characterization and Assessment of...
as beta-bisabolene and zingiberene, zingerone, shogaols, and gingerols with [6]-gingerol (1-[4'-hydroxy-3'-methoxyphenyl]-5-hydroxy-3-decanone) as the...
mouse model. It is used in flavors as an essential oil to give spiciness. Gingerol Shogaol Xavier Fernandez; Christine Pintaric; Louisette Lizzani-Cuvelier;...
reaction forming zingiberene as well as other mono- and sesquiterpenes. Gingerol sequiphellandrene Herout, Vlastimil; Benesova, Vera; Pliva, Josef (1953)...
Trimethobenzamide is thought to work on the CTZ Ginger contains 5-HT3 antagonists gingerols, shogaols, and galanolactone. Preliminary clinical data suggests ginger...
or drying of the ginger root, which causes a reverse aldol reaction on gingerol. Zingerone was first isolated from the ginger root in 1917 by Hiroshi Nomura...