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Trofimov Reaction information


Trofimov Reaction
Named after Boris Trofimov
Reaction type Ring forming reaction

In organic chemistry, the Trofimov Reaction is a reaction used to synthesize [2,3] disubstituted pyrroles from ketoximes and acetylene using the superbase medium potassium hydroxide and dimethyl sulfoxide. The reaction is named after Boris Trofimov who first reported it in the 1970's.[1]

  1. ^ Trofimov, Boris A (1981-02-28). "Reactions of Acetylene in Superbasic Media". Russian Chemical Reviews. 50 (2): 138–150. Bibcode:1981RuCRv..50..138T. doi:10.1070/RC1981v050n02ABEH002551. ISSN 0036-021X. S2CID 250826279.

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Trofimov Reaction

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In organic chemistry, the Trofimov Reaction is a reaction used to synthesize [2,3] disubstituted pyrroles from ketoximes and acetylene using the superbase...

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Favorskii reaction

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The Favorskii reaction is an organic chemistry reaction between an alkyne and a carbonyl group, under basic conditions. The reaction was discovered in...

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Organophosphine

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1002/anie.200602143. PMID 17022105. Arbuzova, S. N.; Gusarova, N. K.; Trofimov, B. A. (2006). "Nucleophilic and free-radical additions of phosphines and...

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Alkynylation

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In organic chemistry, alkynylation is an addition reaction in which a terminal alkyne (−C≡CH) is added to a carbonyl group (C=O) to form an α-alkynyl alcohol...

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Diacetylene

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15227/orgsyn.065.0052. Maretina, Irina A; Trofimov, Boris A (2000). "Diacetylene: a candidate for industrially important reactions". Russian Chemical Reviews. 69...

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Thiocyanate

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Khrenova, Maria G.; Muyzer, Gerard; Rakitina, Tatiana V.; Shabalin, Ivan G.; Trofimov, Anton A.; Tsallagov, Stanislav I.; Popov, Vladimir O. (2020). "Trinuclear...

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Divinyl sulfide

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Reviews. 114 (3): 1761–1782. doi:10.1021/cr400357r. PMID 24228942. Boris A. Trofimov; S. V. Amosova (1984). "Divinyl Sulfide: Synthesis, Properties, and Applications"...

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Azomethine ylide

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1021/ja905302f. PMID 19736987. Nedolya, N. A.; Trofimov, B. A. (2013). "[1,7]-Electrocyclization reactions in the synthesis of azepine derivatives". Chemistry...

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Tributylphosphine

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Tributylphosphine is moderately toxic, with an LD50 of 750 mg/kg (oral, rats). Trofimov, Boris A.; Arbuzova, Svetlana N.; Gusarova, Nina K. (1999). "Phosphine...

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Phosphine

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Bibcode:2021NatAs...5..636G. doi:10.1038/s41550-021-01424-x. S2CID 233296859. Trofimov, Boris A.; Arbuzova, Svetlana N.; Gusarova, Nina K. (1999). "Phosphine...

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2024 Israeli strikes on Iran

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Archived from the original on 14 April 2024. Retrieved 14 April 2024. Trofimov, Yaroslav. "Analysis: Israel Repelled Iran's Huge Attack. But Only With...

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Hydrophosphination

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hydrofunctionalizations, the rate and regiochemistry of the insertion reaction is influenced by the catalyst. Catalysts take many forms, but most prevalent...

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2023 Bryansk Oblast military aircraft crashes

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aircraft were shot down". The Wall Street Journal correspondent Yaroslav Trofimov suggested this incident constituted the "worst day for the Russian military...

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Transition metal complexes of thiocyanate

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Khrenova, Maria G.; Muyzer, Gerard; Rakitina, Tatiana V.; Shabalin, Ivan G.; Trofimov, Anton A.; Tsallagov, Stanislav I.; Popov, Vladimir O. (2020). "Trinuclear...

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2024 Iranian strikes against Israel

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Archived from the original on 14 April 2024. Retrieved 14 April 2024. Trofimov, Yaroslav. "Analysis: Israel Repelled Iran's Huge Attack. But Only With...

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Gidazepam

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Akusherka. 56 (9): 35–7. PMID 1684941. Neznamov GG, Koshelev VV, Voronina TA, Trofimov SS (Mar 2002). "[Experimental and clinical rationale for complex treatment...

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Cyanoethylation

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Catalysis Today. 44 (1–4): 277–283. doi:10.1016/S0920-5861(98)00200-4.. Trofimov, Boris A.; Arbuzova, Svetlana N.; Gusarova, Nina K. (1999). "Phosphine...

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Diallyl disulfide

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Sigalov, M.V.; Sinegovskaya, L.M.; Trofimov, B.A. (1986). "Synthesis of 1-alkylthio-3-allylthio-1-propenes by the reaction of dialllyl disulfide with allyl...

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Thiocyanate hydrolase

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Khrenova, Maria G.; Muyzer, Gerard; Rakitina, Tatiana V.; Shabalin, Ivan G.; Trofimov, Anton A.; Tsallagov, Stanislav I.; Popov, Vladimir O. (2020). "Trinuclear...

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2018 Armenian Revolution

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commentators such as Carl Bildt, Anders Åslund, Ian Bremmer, Yaroslav Trofimov, Ben Judah, and others. Belarusian journalist Franak Viačorka criticized...

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Russian Constituent Assembly

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Russia in War and Revolution, 1914-1922, edited by Jonathan Daly and Leonid Trofimov (Indianapolis: Hackett, 2009), 214-5. Fyodor Fyodorovich Raskolnikov, selection...

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Islamic State

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Its Ranks Expand". The Wall Street Journal. Retrieved 11 April 2015.  • Trofimov, Yaroslav (4 February 2015). "In Islamic State Stronghold of Raqqa, Foreign...

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Freedom of Russia Legion

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from the original on 2023-05-23. Retrieved 2023-05-24. Coles, Isabel; Trofimov, Yaroslav (7 April 2022). "Belarusians, Russians Join Ukraine's Military...

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2021 Kabul airport attack

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responsibility for Kabul airport blasts". The Guardian. Retrieved 30 August 2021. Trofimov, Yaroslav; Salama, Vivian (27 August 2021). "In Its Last Days in Kabul...

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