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Thiocyanate hydrolase information


thiocyanate hydrolase
Identifiers
EC no.3.5.5.8
Databases
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BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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A thiocyanate hydrolase (EC 3.5.5.8) is an enzyme belonging to the family of hydrolases. The systematic name of this enzyme class is thiocyanate aminohydrolase. This enzyme catalyzes the chemical reaction:

SCN + 2 H2O + H+ ⇌ SCO + NH3

The mechanism is proposed to involve a metal thiocyanate complex.

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Thiocyanate hydrolase

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A thiocyanate hydrolase (EC 3.5.5.8) is an enzyme belonging to the family of hydrolases. The systematic name of this enzyme class is thiocyanate aminohydrolase...

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Transition metal complexes of thiocyanate

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enzymes. Two metalloenzymes, thiocyanate hydrolases, catalyze the hydrolysis of thiocyanate. A cobalt-containing hydrolase catalyzes its conversion to...

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Thiocyanate

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colourless salts potassium thiocyanate and sodium thiocyanate. Mercury(II) thiocyanate was formerly used in pyrotechnics. Thiocyanate is analogous to the cyanate...

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Carbonyl sulfide hydrolase

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concentrations both in vivo and in vitro. Thiocyanate hydrolase (SCNase) found in THI115 initiates enzymatic formation of thiocyanate (SCN−). SCNase hydrolyzes SCN−...

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Rhodanese

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and ubiquitin C-terminal hydrolases. This reaction is important for the treatment of exposure to cyanide, since the thiocyanate formed is around 1 / 200...

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Cyanide

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hydrogenases proceeds from carbamoyl phosphate, which converts to cysteinyl thiocyanate, the CN− donor. The cyanide radical •CN has been identified in interstellar...

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Myrosinase

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from a glucosinolate. The remaining molecule then quickly converts to a thiocyanate, an isothiocyanate, or a nitrile; these are the active substances that...

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Normally, the protein allows movement of chloride, bicarbonate and thiocyanate ions (with a negative charge) out of an epithelial cell into the Airway...

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Epoxide

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Epoxides are alkylating agents, making many of them highly toxic. Epoxide hydrolase Juliá–Colonna epoxidation Massingill, J. L.; Bauer, R. S. (2000-01-01)...

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Benzene

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variant of NAD(P)H:quinone oxidoreductase 1 (NQO1), microsomal epoxide hydrolase (EPHX) and deletion of the glutathione S-transferase T1 (GSTT1) showed...

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Ribonuclease inhibitor

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differential cytotoxicity against cancer cells. Biology portal Guanidinium thiocyanate - a chemical RNase inhibitor. PDB: 2BNH​; Kobe B, Deisenhofer J (1993)...

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Tyrosine

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Fumarylacetoacetate is finally split by the enzyme fumarylacetoacetate hydrolase through the addition of a water molecule. Thereby fumarate (also a metabolite...

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Naturally occurring phenols

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Aryldialkylphosphatase (also known as organophosphorus hydrolase, phosphotriesterase, and paraoxon hydrolase) uses an aryl dialkyl phosphate and H2O to produce...

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Glycidamide

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glyceramide both spontaneously or enzymatically by microsomal epoxide hydrolase. This too can be excreted through urine. Mice and rats show mutations...

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Genistein

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FAAHTooltip Fatty acid amide hydrolase Inhibitors: 4-Nonylphenylboronic acid AACOCF3 AM-404 Arachidonoyl serotonin BIA 10-2474 Biochanin A Genistein IDFP...

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