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Triple helix information


a molecular model of the collagen triple helix
The collagen triple helix is a triple helix formed from three separate protein helices, spiraling around the same axis.

In the fields of geometry and biochemistry, a triple helix (pl.: triple helices) is a set of three congruent geometrical helices with the same axis, differing by a translation along the axis. This means that each of the helices keeps the same distance from the central axis. As with a single helix, a triple helix may be characterized by its pitch, diameter, and handedness. Examples of triple helices include triplex DNA,[1] triplex RNA,[2] the collagen helix,[3] and collagen-like proteins.

  1. ^ Bernués J, Azorín F (1995). "Triple-Stranded DNA". Nucleic Acids and Molecular Biology. Vol. 9. Berlin, Heidelberg: Springer. pp. 1–21. doi:10.1007/978-3-642-79488-9_1. ISBN 978-3-642-79490-2.
  2. ^ Buske FA, Mattick JS, Bailey TL (May 2011). "Potential in vivo roles of nucleic acid triple-helices". RNA Biology. 8 (3): 427–439. doi:10.4161/rna.8.3.14999. PMC 3218511. PMID 21525785.
  3. ^ Bächinger HP (2005-05-03). Collagen: Primer in Structure, Processing and Assembly. Springer Science & Business Media. ISBN 9783540232728.

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Triple helix

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In the fields of geometry and biochemistry, a triple helix (pl.: triple helices) is a set of three congruent geometrical helices with the same axis, differing...

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consists of amino acids bound together to form a triple helix of elongated fibril known as a collagen helix. It is mostly found in connective tissue such...

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(October 1995). "Binding of RecA to anti-parallel poly(dA).2poly(dT) triple helix DNA". Biochim Biophys Acta. 1264 (1): 129–33. doi:10.1016/0167-4781(95)00137-6...

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A helix (/ˈhiːlɪks/; pl. helices) is a shape like the cylindrical part of a coil spring or machine screw. It is a type of smooth space curve with tangent...

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Nucleic acid notation

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"•" or a "-" or a "." (example: A•T, or poly(rC)•2poly(rC)). Hoogsteen triple helix base pairs are indicated by a "*" or a ":" (example: C•G*G+, or T•A*T...

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strands in tissues by forming a hybridized triple helix with the collagen strands. This occurs via the triple helical chain assembly and inter-chain hydrogen...

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modification of the proline residue increases the stability of the collagen triple helix. It was initially proposed that the stabilization was due to water molecules...

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DNA was helical with either two or three stands, they constructed a triple helix model, which was immediately proven to be flawed. In particular, the...

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Collagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. This locus encodes a protein that may play a role...

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in the sociology of communication and innovation, especially for his Triple helix model of innovation developed with Henry Etzkowitz in the 1990s. Leydesdorff...

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repeats; these can form unusual secondary structures, such as a collagen helix. The structures often feature cross-links between chains (e.g., cys-cys...

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which acts as an RNA stabilization element through triple helix formation with the poly(A) tail. Triple-stranded DNA is also possible from Hoogsteen or reversed...

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is produced by separating the three strands in each collagen fiber's triple helix by boiling collagen in water. Rabbi David Sheinkopf, author of Gelatin...

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level of smartness under the Triple Helix Metric, finding a strong positive correlation. A live example of the Triple Helix Model in practice can be seen...

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