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Treponema pallidum information


Treponema pallidum
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Spirochaetota
Class: Spirochaetia
Order: Spirochaetales
Family: Treponemataceae
Genus: Treponema
Species:
T. pallidum
Binomial name
Treponema pallidum
Schaudinn & Hoffmann, 1905

Treponema pallidum, formerly known as Spirochaeta pallida, is a microaerophilic spirochaete bacterium with subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. It is transmitted only among humans.[1] It is a helically coiled microorganism usually 6–15 μm long and 0.1–0.2 μm wide.[1] T. pallidum's lack of either a tricarboxylic acid cycle or oxidative phosphorylation results in minimal metabolic activity.[2] The treponemes have a cytoplasmic and an outer membrane. Using light microscopy, treponemes are visible only by using dark-field illumination. T. pallidum consists of three subspecies, T. p. pallidum, T. p. endemicum, and T. p. pertenue, each of which has a distinct associated disease.[3]

  1. ^ a b Radolf JD (1996). Baron S (ed.). Treponema (4th ed.). Galveston (TX): University of Texas Medical Branch at Galveston. ISBN 978-0963117212. PMID 21413263. Retrieved 13 February 2019.
  2. ^ Norris SJ, Cox DL, Weinstock GM (2001). "Biology of Treponema pallidum: Correlation of Functional Activities With Genome Sequence Data" (PDF). JMMB Review. 3 (1): 37–62. PMID 11200228.
  3. ^ Centurion-Lara A, Molini BJ, Godornes C, Sun E, Hevner K, Voorhis WC, Lukehart SA (1 September 2006). "Molecular Differentiation of Treponema pallidum Subspecies". Journal of Clinical Microbiology. 44 (9): 3377–3380. doi:10.1128/JCM.00784-06. ISSN 0095-1137. PMC 1594706. PMID 16954278.

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