Treponema pallidum, formerly known as Spirochaeta pallida, is a microaerophilic spirochaete bacterium with subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. It is transmitted only among humans.[1] It is a helically coiled microorganism usually 6–15 μm long and 0.1–0.2 μm wide.[1]T. pallidum's lack of either a tricarboxylic acid cycle or oxidative phosphorylation results in minimal metabolic activity.[2] The treponemes have a cytoplasmic and an outer membrane. Using light microscopy, treponemes are visible only by using dark-field illumination. T. pallidum consists of three subspecies, T. p. pallidum, T. p. endemicum, and T. p. pertenue, each of which has a distinct associated disease.[3]
^ abRadolf JD (1996). Baron S (ed.). Treponema (4th ed.). Galveston (TX): University of Texas Medical Branch at Galveston. ISBN 978-0963117212. PMID 21413263. Retrieved 13 February 2019.
^Norris SJ, Cox DL, Weinstock GM (2001). "Biology of Treponema pallidum: Correlation of Functional Activities With Genome Sequence Data" (PDF). JMMB Review. 3 (1): 37–62. PMID 11200228.
^Centurion-Lara A, Molini BJ, Godornes C, Sun E, Hevner K, Voorhis WC, Lukehart SA (1 September 2006). "Molecular Differentiation of Treponema pallidum Subspecies". Journal of Clinical Microbiology. 44 (9): 3377–3380. doi:10.1128/JCM.00784-06. ISSN 0095-1137. PMC 1594706. PMID 16954278.
and 27 Related for: Treponema pallidum information
Treponemapallidum, formerly known as Spirochaeta pallida, is a microaerophilic spirochaete bacterium with subspecies that cause the diseases syphilis...
Treponema is a genus of spiral-shaped bacteria. The major treponeme species of human pathogens is Treponemapallidum, whose subspecies are responsible...
The Treponemapallidum particle agglutination assay (also called TPPA test) is an indirect agglutination assay used for detection and titration of antibodies...
sexually transmitted infection caused by the bacterium Treponemapallidum subspecies pallidum. The signs and symptoms of syphilis vary depending in which...
of the skin, bones, and joints caused by the spirochete bacterium Treponemapallidum pertenue. The disease begins with a round, hard swelling of the skin...
related to the syphilis-causing obligate human pathogen, Treponemapallidum subsp. pallidum. It has also been isolated from women with bacterial vaginosis...
Italian physician and poet Girolamo Fracastoro. The causative organism, Treponemapallidum, was first identified by Fritz Schaudinn and Erich Hoffmann in 1905...
(CSF) for analysis. The CSF is tested for antibodies for specific Treponemapallidum antigens. The preferred test is the VDRL test, which is sometimes...
form of syphilis infection that affects the central nervous system. Treponemapallidum, a spirochate bacterium, is the main cause of syphilis, which spreads...
infectious lesion forms around 21 days after the initial exposure to Treponemapallidum, the gram-negative spirochaete bacterium causing syphilis, but can...
caused by infection by the endemicum subspecies of the spirochete Treponemapallidum. Bejel is one of the "endemic treponematoses" (endemic infections...
bacterium itself, Treponemapallidum, but rather for antibodies against substances released by cells when they are damaged by T. pallidum (cardiolipin and...
Lyme disease. Borrelia recurrentis, which causes relapsing fever Treponemapallidum subspecies which cause treponematoses such as syphilis and yaws. Brachyspira...
Cruelty to Animals. In 1913, Noguchi demonstrated the presence of Treponemapallidum (syphilitic spirochete) in the brain of a progressive paralysis patient...
genus Treponema. The four diseases are collectively referred to as treponematoses: Syphilis (Treponemapallidumpallidum) Yaws (Treponemapallidum pertenue)...
burgdorferi, a tick-borne bacterium that causes Lyme disease Treponema species, such as Treponemapallidum, subspecies of which causes treponematoses, including...
symptoms of the secondary phase of syphilis, caused by the spirochete Treponemapallidum. Condylomata lata occurs in about one-third of secondary syphilis...
2020-09-25. Retrieved 2015-05-12. Fantry, Lori E.; Tramont, Edmund C. "TreponemaPallidum (Syphilis)". Archived from the original on 2015-03-12. Retrieved 2015-05-12...
Bordetella pertussis, Fusobacterium sp., Corynebacterium diphtheriae, Treponemapallidum, and Neisseria gonorrhoeae. Anaerobic bacteria have been implicated...
to treat the disease syphilis because it is toxic to the bacterium Treponemapallidum, a spirochete that causes syphilis. Arsphenamine was originally called...
of suppurative adenopathy is almost pathognomonic. No evidence of Treponemapallidum infection by darkfield microscopic examination of ulcer exudate or...
reagent of Dieterle stain is silver nitrate. It can stain microbes like Treponemapallidum in grey or black and background in yellow. It is used to find the...
et al. (May 2008). Hall N (ed.). "The binary protein interactome of Treponemapallidum--the syphilis spirochete". PLOS ONE. 3 (5): e2292. Bibcode:2008PLoSO...
that are difficult to culture by routine laboratory methods, like Treponemapallidum (the causative agent of syphilis), or viruses. The presence of antibodies...
B. anserina, and the other known type of spirochete at the time, Treponemapallidum. This bacterium must be viewed using dark-field microscopy, which...
a diagnostic test for syphilis. Using antibodies specific for the Treponemapallidum species, such tests would be assumed to be more specific than non-treponemal...