Trefoil factor 2 is a protein that in humans is encoded by the TFF2 gene.[5][6][7]
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.[7]
^ abcGRCh38: Ensembl release 89: ENSG00000160181 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000024028 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Tomasetto C, Rockel N, Mattei MG, Fujita R, Rio MC (Sep 1992). "The gene encoding the human spasmolytic protein (SML1/hSP) is in 21q 22.3, physically linked to the homologous breast cancer marker gene BCEI/pS2". Genomics. 13 (4): 1328–30. doi:10.1016/0888-7543(92)90059-2. PMID 1505966.
Trefoilfactor2 is a protein that in humans is encoded by the TFF2 gene. Members of the trefoil family are characterized by having at least one copy of...
Trefoilfactor 3 is a protein that in humans is encoded by the TFF3 gene. Members of the trefoil family are characterized by having at least one copy of...
Trefoilfactor 1 is a protein that in humans is encoded by the TFF1 gene (also called pS2 gene). Members of the trefoil family are characterized by having...
in Phase 2 trials for major depressive disorder. In November 2021, Tonix was issued the Patent No. 11, 167, 010, titled “Trefoil Family Factor Proteins...
The trefoil knot fold is a protein fold in which the protein backbone is twisted into a trefoil knot shape. "Shallow" knots in which the tail of the polypeptide...
"beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors". Journal...
from orphan sources, a common factor reappeared: individuals who encountered the source were unfamiliar with the trefoil radiation warning symbol, and...
and in fibroblast growth factors 1 and 2. CATH Architecture "Beta Trefoil" Murzin AG, Lesk AM, Chothia C (Jan 1992). "β-trefoil fold: patterns of structure...
simplest nontrivial example is the (2,3)-torus knot, also known as the trefoil knot. A torus knot can be rendered geometrically in multiple ways which...
knot group of the trefoil knot. The quotients by congruence subgroups are of significant interest. Other important quotients are the (2, 3, n) triangle...
almost always has three leaflets (trifoliolate); hence the popular name "trefoil". The species name, repens, is Latin for "creeping". It is a herbaceous...
anything in reality. The international radioactivity symbol (also known as trefoil) first appeared in 1946, at the University of California, Berkeley Radiation...
that has mass (such as an electron, alpha particle, or other type). The trefoil symbol used to warn of presence of radioactive material or ionising radiation...
headwear. Distinctive uniform insignia include the fleur-de-lis and the trefoil, as well as merit badges and other patches. In 1907, Robert Baden-Powell...
certain numbers with any given knot; these numbers are different for the trefoil knot, the figure-eight knot, and the unknot (a simple loop), showing that...
shelters. These buildings were placarded with the orange-yellow and black trefoil sign designed by United States Army Corps of Engineers director of administrative...
inhibitors of the Kunitz family, the Kunitz-STI protein family, include a beta trefoil fold. PDB: 1KTH; Arnoux B, Ducruix A, Prangé T (July 2002). "Anisotropic...
branches all maintain some variation of a navy-blue shirt or tunic with a trefoil, with optional sashes and scarves. Jennifer S.H. Brown. "Beaver Pelts"...
prompted the IAEA to re-evaluate the effectiveness of the radioactive hazard trefoil as a warning symbol. Although the symbol was displayed on the teletherapy...
"beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors". Journal...
higher-order aberrations, of which only spherical aberration, coma and trefoil are of clinical interest. Spherical aberration is a term used clinically...
published in 2008. Hazardous levels of ionizing radiation are signified by the trefoil sign on a yellow background. These are usually posted at the boundary of...
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