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Machine perfusion (MP) is a technique used in organ transplantation as a means of preserving the organs which are to be transplanted.
Machine perfusion has various forms and can be categorised according to the temperature of the perfusate: cold (4 °C) and warm (37 °C).[1] Machine perfusion has been applied to renal transplantation,[2] liver transplantation[3] and lung transplantation.[4] It is an alternative to static cold storage (SCS).
^Kay, Mark D.; Hosgood, Sarah A.; Harper, Simon J.F.; Bagul, Atul; Waller, Helen L.; Nicholson, Michael L. (November 2011). "Normothermic Versus Hypothermic Ex Vivo Flush Using a Novel Phosphate-Free Preservation Solution (AQIX) in Porcine Kidneys". Journal of Surgical Research. 171 (1): 275–282. doi:10.1016/j.jss.2010.01.018. PMID 20421110.
^Yong, Cissy; Hosgood, Sarah A.; Nicholson, Michael L. (June 2016). "Ex-vivo normothermic perfusion in renal transplantation: past, present and future". Current Opinion in Organ Transplantation. 21 (3): 301–307. doi:10.1097/MOT.0000000000000316. ISSN 1087-2418. PMID 27145197. S2CID 22627245.
^Ceresa, Carlo D. L.; Nasralla, David; Coussios, Constantin C.; Friend, Peter J. (February 2018). "The case for normothermic machine perfusion in liver transplantation: Ceresa et al". Liver Transplantation. 24 (2): 269–275. doi:10.1002/lt.25000. PMID 29272051.
^Cypel, Marcelo; Yeung, Jonathan C.; Liu, Mingyao; Anraku, Masaki; Chen, Fengshi; Karolak, Wojtek; Sato, Masaaki; Laratta, Jane; Azad, Sassan; Madonik, Mindy; Chow, Chung-Wai (2011-04-14). "Normothermic Ex Vivo Lung Perfusion in Clinical Lung Transplantation" (PDF). New England Journal of Medicine. 364 (15): 1431–1440. doi:10.1056/NEJMoa1014597. ISSN 0028-4793. PMID 21488765. S2CID 10576812. Archived from the original (PDF) on 2020-02-22.
Machineperfusion (MP) is a technique used in organ transplantation as a means of preserving the organs which are to be transplanted. Machine perfusion...
to a capillary bed in tissue. Perfusion may also refer to fixation via perfusion, used in histological studies. Perfusion is measured as the rate at which...
body while bypassing the heart and lungs. Additionally, it maintains perfusion to other body organs and tissues of the patient while the surgeon works...
doctor or clinical perfusion scientist, is a healthcare professional who operates the cardiopulmonary bypass machine (heart–lung machine) during cardiac...
were similar with both approaches. Machineperfusion prior to transplant is associated with decreased tissue re-perfusion ischemic injury (a process in which...
technique involves machineperfusion of the organ at either hypothermic (4-10 °C) or normothermic (37 °C) temperatures. Hypothermic perfusion of kidneys is...
tubing that is not so easily disconnected. Hose barbs are used in machineperfusion and chemistry laboratory equipment. Hose barb fittings are small curved...
between the pulsatile and baseline absorbance ("perfusion index") can be used to evaluate perfusion. SpO 2 = HbO 2 HbO 2 + Hb {\displaystyle {\ce {SpO_2}}={\frac...
factor for graft failure in the future. Hypothermic pulsatile machineperfusion; using a machine to perfuse donor kidneys ex vivo with cold solution, rather...
Gaseous oxygen perfusion/persufflation can enhance organ preservation relative to static cold storage or hypothermic machineperfusion, since the lower...
into the brain, known as cerebral perfusion pressure, which is determined by the body's blood pressure. Cerebral perfusion pressure (CPP) is defined as the...
Minusheet perfusion culture system is used for advanced cell culture experiments in combination with adherent cells and to generate specialized tissues...
to two weeks. Coupled with imaging of cerebral perfusion, researchers can highlight regions of "perfusion/diffusion mismatch" that may indicate regions...
the miracle of organ donation and cutting-edge medical advances in machineperfusion — a portable platform that keeps organs alive outside of the body...
the condition. Otherwise, a CT pulmonary angiography, lung ventilation/perfusion scan, or ultrasound of the legs may confirm the diagnosis. Together, deep...
techniques as local hyperthermia treatment, or it may rely on blood perfusion. In blood perfusion, the patient's blood is removed from the body, heated up, and...
research fellowship in the therapeutic manipulation of organs using machineperfusion technology and the use of 3D printing in complex transplant surgery...
neighbouring cells through diffusion and into the systemic circulation through perfusion. Increased skin permeability under irradiation exacerbates this possibility...
Theoretically, the application of ECPR allows for the return of cerebral perfusion in a more sustainable manner than with external compressions alone. By...
than usually <12 hours) of human transplant organ preservation with machineperfusion of a liver is reported. It could possibly be extended to 10 days and...
This may also be used on the brain, where CT perfusion imaging can often detect poor brain perfusion well before it is detected using a conventional...
caused by five categories of etiologies: hypoventilation, ventilation/perfusion mismatch, right-to-left shunt, diffusion impairment, and low PO2. Low...
moderate endometriosis. In non-tubal sub fertility, fallopian tube sperm perfusion may be the preferred technique over intrauterine insemination. Intratubal...
orientations. Contrast medium is given intravenously to assess myocardial perfusion and LGE. Phase contrast imaging may be used to quantify valvular regurgitant...
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