The 4 substrates of this enzyme are toluene, NADH, H+, and O2, whereas its two products are (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol and NAD+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of two atoms o oxygen into the other donor. The systematic name of this enzyme class is toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating). This enzyme is also called toluene 2,3-dioxygenase. This enzyme participates in toluene and xylene degradation.
and 18 Related for: Toluene dioxygenase information
In enzymology, a toluenedioxygenase (EC 1.14.12.11) is an enzyme that catalyzes the chemical reaction toluene + NADH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons...
a variety of halogenated compounds including trichloroethylene. Toluenedioxygenase has been reported to be involved in TCE degradation by Pseudomonas...
and butane) to aromatics. Toluene hydrodealkylation converts toluene to benzene. In this hydrogen-intensive process, toluene is mixed with hydrogen, then...
natural product, via a reaction pathway initiated by terephthalate 1,2-dioxygenase. Combined with the previously known PETase and MHETase, a full pathway...
no added base is needed to form the complex. The enzyme acetylacetone dioxygenase cleaves the carbon-carbon bond of acetylacetone, producing acetate and...
first oxidized to its sulfinic acid, catalyzed by the enzyme cysteine dioxygenase. Cysteine sulfinic acid, in turn, is decarboxylated by sulfinoalanine...
its ability to metabolize harmful environmental pollutants, including toluene, naphthalene, herbicides, and PCBs. Rhodococcus species typically metabolize...
by the enzyme tryptophan dioxygenase, which is made primarily but not exclusively in the liver, and indoleamine 2,3-dioxygenase, which is made in many tissues...
bacteria have two fundamental characteristics: (1) specific membrane-bound dioxygenases and (2) mechanisms for optimizing contact with water-insoluble hydrocarbons...
enzymes, namely indoleamine 2,3-dioxygenase (IDO) in the immune system and the brain, and tryptophan 2,3-dioxygenase (TDO) in the liver, are responsible...
first oxidized to its sulfinic acid, catalyzed by the enzyme cysteine dioxygenase. Cysteine sulfinic acid, in turn, is decarboxylated by sulfinoalanine...
contains an annotated N-prenyltransferase, α-ketoglutarate (αKG)-dependent dioxygenase, and several retrotransposable elements. To confirm production of kainic...
result of activation of indoleamine dioxygenases (to be specific, IDO-1 and IDO-2) as well as tryptophan 2,3-dioxygenase (TDO) stimulation by inflammatory...
examples of true redundancy. For example, the multiplicity of ring-cleaving dioxygenases in certain rhodococcal isolates may be attributed to the cryptic aromatic...
expression. Studies with histone deactylase complex inhibitors like SAHA, toluene, garcinol, trichostatin A and sodium butyrate have shown that acetylation...
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