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Tocopherol information


Tocopherols (/tˈkɒfəˌrɒl/;[1] TCP) are a class of organic compounds comprising various methylated phenols, many of which have vitamin E activity. Because the vitamin activity was first identified in 1936 from a dietary fertility factor in rats, it was named tocopherol, from Greek τόκος tókos 'birth' and φέρειν phérein 'to bear or carry', that is 'to carry a pregnancy', with the ending -ol signifying its status as a chemical alcohol.

α-Tocopherol is the main source found in supplements and in the European diet, where the main dietary sources are olive and sunflower oils,[2] while γ-tocopherol is the most common form in the American diet due to a higher intake of soybean and corn oil.[2][3]

Tocotrienols, which are related compounds, also have vitamin E activity. All of these various derivatives with vitamin activity may correctly be referred to as "vitamin E". Tocopherols and tocotrienols are fat-soluble antioxidants but also seem to have many other functions in the body.

  1. ^ "Tocopherol". Dictionary.com Unabridged (Online). n.d. Retrieved 28 February 2018.
  2. ^ a b Wagner KH, Kamal-Eldin A, Elmadfa I (2004). "Gamma-tocopherol--an underestimated vitamin?". Annals of Nutrition & Metabolism. 48 (3): 169–88. doi:10.1159/000079555. PMID 15256801. S2CID 24827255. In North America, the intake of γ-tocopherol has been estimated to exceed that of α-tocopherol by a factor of 2–4 ... due to the fact that soybean oil is the predominant vegetable oil in the American diet (76.4%) followed by corn oil and canola oil (both 7%) ... The supply of dietary fats ... is much more diverse in Europe ... The oils mainly consumed in Europe, i.e. sunflower, olive and canola oil, provide less γ-tocopherol but more α-tocopherol ... [T]he ratio of α-:γ-tocopherol is at least 1:2. Therefore, the average γ-tocopherol intake may be estimated as 4–6 mg/day, which is about 25–35% of the USA intake. In accordance with the lower estimated European intake of γ-tocopherol, the serum levels of γ-tocopherol in European populations are 4–20 times lower than that of α-tocopherol
  3. ^ Cite error: The named reference gamma was invoked but never defined (see the help page).

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Tocopherol

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Tocopherols (/toʊˈkɒfəˌrɒl/; TCP) are a class of organic compounds comprising various methylated phenols, many of which have vitamin E activity. Because...

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Vitamin E is a group of eight fat soluble compounds that include four tocopherols and four tocotrienols. Vitamin E deficiency, which is rare and usually...

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Tocotrienol

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delta) and four tocopherols (alpha, beta, gamma, delta). The critical chemical structural difference between tocotrienols and tocopherols is that tocotrienols...

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Sacha inchi oil

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very high content of Tocopherols (176–226 mg/100 g) which consists predominantly of gamma-Tocopherol (50%) and delta-Tocopherol. While Sacha Inchi is...

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Pentoxifylline

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of internal medicine (diabetology and angiology). The combination of tocopherol and pentoxifylline has been evaluated for the treatment of medication-related...

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Chirality

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plant form of alpha-tocopherol (vitamin E) is RRR-α-tocopherol whereas the synthetic form (all-racemic vitamin E, or dl-tocopherol) is equal parts of the...

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Pumpkin seed

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total fat content ranged from 11% to 52%. Based on the quantity of alpha-tocopherol extracted in the oil, the vitamin E content of twelve C. maxima cultivar...

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Vitamer

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properties than α-tocopherol and can have metabolic impacts at low concentration.[citation needed] Normal serum concentrations of α-tocopherol in adults ranges...

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Antioxidant

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non-marine antioxidants such as ascorbic acid (vitamin C), polyphenols, and tocopherols. The evolution of angiosperm plants between 50 and 200 million years...

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Vitamin E deficiency

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isolated with vitamin E deficiency', caused by mutations in the gene for the tocopherol transfer protein. These individuals have an extremely poor capacity to...

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Olive oil

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provide less γ-tocopherol but more α-tocopherol ... [T]he ratio of α-:γ-tocopherol is at least 1:2. Therefore, the average γ-tocopherol intake can be estimated...

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Sea buckthorn oil

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fatty acids and carotenoids. Both oils also contain dense amounts of tocopherols, tocotrienols and plant sterols. Oils from sea buckthorn seeds and pulp...

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Tayberry

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1.6E-29 g Alpha-Tocopherol 8.7E-16 g Lutein & zeaxanthin 1.36E-28 g Beta-tocopherol 0 g 0 Gamma-tocopherol 1.42E-15 g Delta-tocopherol 1.04E-15 g Vitamin...

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International unit

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025 μg D2/D3 ≈ 0.65 pmol 1 IU Vitamin E = 2⁄3 mg d-alpha-tocopherol = 0.90 mg of dl-alpha-tocopherol In 1931, the Permanent Commission on Biological Standardisation...

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Apricot oil

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dry kernel matter. Thiamine, Riboflavin, Niacin, Vitamin C, δ-Tocopherol, α-Tocopherol Alpaslan, M.; Hayta, M. (May 2006). "Apricot kernel: Physical and...

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called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols. The term vitamin does not include the three other...

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Hydrocarbon

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hydrocarbons constitute the side chains of biomolecules such as chlorophyll and tocopherol. Unsaturated hydrocarbons, which have one or more double or triple bonds...

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Tocofersolan (INN) or tocophersolan, also referred to as TPGS (for tocopherol polyethylene glycol succinate), is a synthetic water-soluble version of vitamin...

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Limonene

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Campesterol Citrostadienol Cycloartenol Sitostanol Sitosterol Stigmasterol Tocopherols Cholesterol Testosterone Cholecalciferol Ecdysones Other Betulin Lanosterol...

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TTPAL

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Tocopherol (alpha) transfer protein-like is a protein that in humans is encoded by the TTPAL gene. "Entrez Gene: Tocopherol (alpha) transfer protein-like"...

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