High magnification micrograph of a thecoma. H&E stain.
Specialty
Oncology
Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours.
They are typically estrogen-producing and they occur in older women (mean age 59; 84% after menopause). (They can, however, appear before menopause.[1])
60% of patients present with abnormal uterine bleeding, and 20% have endometrial carcinoma.
^Okada I, Nakagawa S, Takemura Y, et al. (October 2004). "Ovarian thecoma associated in the first trimester of pregnancy". J. Obstet. Gynaecol. Res. 30 (5): 368–71. doi:10.1111/j.1447-0756.2004.00212.x. PMID 15327450. S2CID 28580115.
Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours...
thecoma but also containing cells typical of steroid hormone-secreting cells were reported. Some of the tumors were classified as luteinized thecomas...
than 5% of ovarian cancers), may both granulosa cells and theca cells. Thecomas are benign proliferations of theca cells that may present with hormonal...
cord-stromal tumor, including estrogen-producing granulosa cell tumor, the benign thecoma, and virilizing Sertoli-Leydig cell tumor or arrhenoblastoma, accounts...
granulosa cell tumor Juvenile granulosa cell tumor The fibroma thecoma family of tumors Thecoma Fibroma Mixed and other sex cord-stromal tumors Mixed sex cord-stromal...
Ronald K.; Smith, Donna; Erşahin, Çağatay (2014). "Fatal Case of Luteinized Thecoma With Sclerosing Peritonitis in a 40-Year-Old Woman". International Journal...
radiotherapy to the pelvis. Specifically, ovarian granulosa cell tumors and thecomas are tumors associated with endometrial cancer. Low immune function has...
hormonal disturbances suggests a Leydig cell tumour, granulosa cell tumour or thecoma. However, hormonal disturbances, in Leydig tumours, is present in only...
tumor with minor sex cord elements M8600/0 Thecoma, NOS Theca cell tumor M8600/3 Thecoma, malignant M8601/0 Thecoma, luteinized M8602/0 Sclerosing stromal...