Tetrahydroharmine (THH) is a fluorescent indole alkaloid that occurs in the tropical liana species Banisteriopsis caapi.[1]
THH, like other harmala alkaloids in B. caapi, namely harmaline and harmine, is a reversible inhibitor of monoamine oxidase A (RIMA),[2] but it also inhibits the reuptake of serotonin.[3]
THH contributes to B. caapi's psychoactivity as a serotonin reuptake inhibitor.[4]
^Callaway JC (June 2005). "Various alkaloid profiles in decoctions of Banisteriopsis caapi". Journal of Psychoactive Drugs. 37 (2): 151–155. doi:10.1080/02791072.2005.10399796. PMID 16149328. S2CID 1420203.
^Buckholtz NS, Boggan WO (November 1977). "Monoamine oxidase inhibition in brain and liver produced by beta-carbolines: structure-activity relationships and substrate specificity". Biochemical Pharmacology. 26 (21). Elsevier BV: 1991–1996. doi:10.1016/0006-2952(77)90007-7. PMID 921812.
^Morales-García JA, de la Fuente Revenga M, Alonso-Gil S, Rodríguez-Franco MI, Feilding A, Perez-Castillo A, Riba J (July 2017). "The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro". Scientific Reports. 7 (1). Springer Science and Business Media LLC: 5309. Bibcode:2017NatSR...7.5309M. doi:10.1038/s41598-017-05407-9. PMC 5509699. PMID 28706205.
^Callaway JC, McKenna DJ, Grob CS, Brito GS, Raymon LP, Poland RE, et al. (June 1999). "Pharmacokinetics of Hoasca alkaloids in healthy humans". Journal of Ethnopharmacology. 65 (3): 243–256. doi:10.1016/S0378-8741(98)00168-8. PMID 10404423.
Tetrahydroharmine (THH) is a fluorescent indole alkaloid that occurs in the tropical liana species Banisteriopsis caapi. THH, like other harmala alkaloids...
related to harmaline, and also found in the vine Banisteriopsis caapi. Tetrahydroharmine is also found in B. caapi and P. harmala. Dr. Alexander Shulgin has...
following harmala alkaloids: Harmine, 0.31–8.43% Harmaline, 0.03–0.83% Tetrahydroharmine, 0.05–2.94% These alkaloids of the beta-carboline class act as monoamine...
caapi is rich with harmala alkaloids, such as harmine, harmaline and tetrahydroharmine (THH), which can act as a monoamine oxidase inhibitor (MAOi). This...
imprisonment for a term not exceeding eighteen months. Harmalol Ibogamine Tetrahydroharmine, a similar harmala alkaloid "Peganum Harmala pamphlet: Syrian Rue"...
etc. Kochia scoparia, Harman; Harmine, etc. Guiera senegalensis, Tetrahydroharmine; Harman, etc. Carex brevicollis, Harmine, etc. Carex parva, Beta-carbolines...
pargyline, as well as the harmala alkaloids like harmine, harmaline, tetrahydroharmine, harmalol, harman, and norharman, which are found to varying degrees...
contain indole alkaloids derived from Beta-carboline such as harmine, tetrahydroharmine, harmaline, manacin, manacein, and dimethyltryptamine and amidine...
can grow from 6 to 12 feet. The plant is a psychedelic, containing tetrahydroharmine (also known as leptaflorin) which is a monoamine oxidase inhibitor...
Cirazoline Dianicline Efaroxan 4-HO-NALT 6-MeO-THH Oxantel Proxyfan Tetrahydroharmine This set index page lists chemical structure articles associated with...
consumed and an MAOI (monoamine oxidase inhibitor), in this case tetrahydroharmine, harmine and harmaline, is needed to allow it to reach the brain in...
include indole alkaloids of the β-carboline group such as harmine, tetrahydroharmine, harmaline, manacine, manaceine, and also derivatives of N,N-dimethyltryptamine...
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