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TRAF1 information


TRAF1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTRAF1, EBI6, MGC:10353, TNF receptor associated factor 1
External IDsOMIM: 601711; MGI: 101836; HomoloGene: 4138; GeneCards: TRAF1; OMA:TRAF1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005658
NM_001190945
NM_001190947

NM_009421
NM_001326601

RefSeq (protein)

NP_001177874
NP_001177876
NP_005649

NP_001313530
NP_033447

Location (UCSC)Chr 9: 120.9 – 120.93 MbChr 2: 34.83 – 34.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TNF receptor-associated factor 1 is a protein that in humans is encoded by the TRAF1 gene.[5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000056558 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026875 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Rothe M, Wong SC, Henzel WJ, Goeddel DV (September 1994). "A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor". Cell. 78 (4): 681–92. doi:10.1016/0092-8674(94)90532-0. PMID 8069916. S2CID 28055231.

and 16 Related for: TRAF1 information

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TRAF1

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receptor-associated factor 1 is a protein that in humans is encoded by the TRAF1 gene. The protein encoded by this gene is a member of the TNF receptor (TNFR)...

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Rheumatoid arthritis

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physical activity) Overweight and obese Genetic factors such as HLA-DR1B1, TRAF1, PSORS1C1 and microRNA 146a are associated with difficult to treat rheumatoid...

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Protein phosphorylation

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phosphorylation of the TNF receptor-associated factor (TRAF1) on serine 139 under specific conditions. Murine TRAF1 is also phosphorylated by the same kinase, which...

Word Count : 7955

Caspase 3

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Welsh K, Matsuzawa S, Stennicke HR, Salvesen GS, Reed JC (March 2001). "TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced...

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TRAF interacting protein

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domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction...

Word Count : 670

TNFAIP3

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endothelial adherens junctions. TNFAIP3 has been shown to interact with TNIP1, TRAF1, TRAF2, IKBKG, TAX1BP1, YWHAB, YWHAZ, TRAF6 and YWHAH. The TNFAIP3 locus...

Word Count : 1971

RELT

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NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence...

Word Count : 341

TNF receptor associated factor

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apoptosis. Currently, seven TRAF proteins have been characterized in mammals: TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6 and TRAF7. Except for TRAF7, these proteins...

Word Count : 136

CD30

Last Update:

Thukral S, Mak TW (Apr 1997). "Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily". Biochemical...

Word Count : 1665

Caspase 8

Last Update:

Caspase-9, DEDD, FADD, FasL, FasR, IFT57, NOL3, PEA15, RIPK1, TNFRSF10B, and TRAF1. Biology portal Caspase FADD The Proteolysis Map GRCh38: Ensembl release...

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Protein kinase N1

Last Update:

Phosphoinositide-dependent kinase-1, Phospholipase D1, RHOA, and Vimentin. TRAF1. GRCh38: Ensembl release 89: ENSG00000123143 – Ensembl, May 2017 GRCm38:...

Word Count : 1759

TRAF2

Last Update:

activation of MAPK8/JNK and NF-κB. The protein complex formed by TRAF2 and TRAF1 interacts with the IAP family members cIAP1 and cIAP2, and functions as...

Word Count : 3427

TRAF3

Last Update:

Welsh K, Matsuzawa S, Stennicke HR, Salvesen GS, Reed JC (March 2001). "TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced...

Word Count : 2200

TNFRSF18

Last Update:

signaling is propagated via recruiting TRAF-family members, specifically TRAF1, TRAF2 and TRAF5, to the GITR-signaling complex. The signaling is then mediated...

Word Count : 2117

RANK

Last Update:

defective coupling between the two. RANK has been shown to interact with: TRAF1, TRAF2, TRAF3, TRAF5, and TRAF6. RANKL Osteoprotegerin Osteoimmunology GRCh38:...

Word Count : 3035

HIVEP3

Last Update:

OMIM] It regulates osteoblasts. HIVEP3 has been shown to interact with TRAF1 and TRAF2. GRCh38: Ensembl release 89: ENSG00000127124 – Ensembl, May 2017...

Word Count : 754

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