TFDP1 information

TFDP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2AZE
Identifiers
Aliases	TFDP1, DP1, DRTF1, Dp-1, DILC, transcription factor Dp-1
External IDs	OMIM: 189902; MGI: 101934; HomoloGene: 38276; GeneCards: TFDP1; OMA:TFDP1 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	113,641,473 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	13,378,448 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; trabecular bone; ; ventricular zone; ; bone marrow; ; stromal cell of endometrium; ; ganglionic eminence; ; rectum; ; olfactory zone of nasal mucosa; ; mucosa of esophagus; ; buccal mucosa cell;
	Top expressed in
	granulocyte; ; epiblast; ; ventricular zone; ; dermis; ; tail of embryo; ; abdominal wall; ; fetal liver hematopoietic progenitor cell; ; hair follicle; ; genital tubercle; ; primitive streak;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein domain specific binding; DNA-binding transcription factor activity; protein binding; transcription coactivator activity; transcription factor binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription regulator complex; nucleus; mitochondrion; nucleoplasm; cytosol; cytoplasm; RNA polymerase II transcription regulator complex;
Biological process	regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; cell cycle; cell population proliferation; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; transcription, DNA-templated; regulation of transcription involved in G1/S transition of mitotic cell cycle; transcription by RNA polymerase II; negative regulation of G0 to G1 transition; positive regulation of transcription by RNA polymerase II; negative regulation of fat cell proliferation; epidermis development; anoikis; positive regulation of transcription, DNA-templated; regulation of cell cycle; regulation of DNA biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	7027
	21781
	ENSG00000198176
	ENSMUSG00000038482
	Q14186
	Q08639
	NM_007111
	NM_001291765; NM_001291766; NM_001291768; NM_009361; NM_001358991
	NP_009042
	NP_001278694; NP_001278695; NP_001278697; NP_033387; NP_001345920
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor Dp-1 is a protein that in humans is encoded by the TFDP1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198176 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038482 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Girling R, Partridge JF, Bandara LR, Burden N, Totty NF, Hsuan JJ, La Thangue NB (Nov 1993). "A new component of the transcription factor DRTF1/E2F". Nature. 365 (6445): 468. Bibcode:1993Natur.365R.468G. doi:10.1038/365468d0. PMID 8413592.
^ Zhang Y, Venkatraj VS, Fischer SG, Warburton D, Chellappan SP (Mar 1997). "Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family". Genomics. 39 (1): 95–8. doi:10.1006/geno.1996.4473. PMID 9027491.
^ "Entrez Gene: TFDP1 transcription factor Dp-1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198176 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038482 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8413592-5] Girling R, Partridge JF, Bandara LR, Burden N, Totty NF, Hsuan JJ, La Thangue NB (Nov 1993). "A new component of the transcription factor DRTF1/E2F". Nature. 365 (6445): 468. Bibcode:1993Natur.365R.468G. doi:10.1038/365468d0. PMID 8413592.

[pmid9027491-6] Zhang Y, Venkatraj VS, Fischer SG, Warburton D, Chellappan SP (Mar 1997). "Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family". Genomics. 39 (1): 95–8. doi:10.1006/geno.1996.4473. PMID 9027491.

[entrez-7] "Entrez Gene: TFDP1 transcription factor Dp-1".

TFDP1 information

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