CDC16 information

CDC16
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3HYM, 4UI9, 5A31, 5G04, 5G05
Identifiers
Aliases	CDC16, ANAPC6, APC6, CUT9, CDC16Hs, cell division cycle 16
External IDs	OMIM: 603461; MGI: 1917207; HomoloGene: 2899; GeneCards: CDC16; OMA:CDC16 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	114,272,723 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	13,781,938 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; body of pancreas; ; canal of the cervix; ; tibial nerve; ; skin of abdomen; ; germinal epithelium; ; gastric mucosa; ; rectum; ; external globus pallidus;
	Top expressed in
	calvaria; ; vas deferens; ; fossa; ; dermis; ; condyle; ; primitive streak; ; abdominal wall; ; ureter; ; maxillary prominence; ; somite;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	microtubule organizing center; nucleus; spindle microtubule; anaphase-promoting complex; cytoskeleton; nucleoplasm; cytosol; cytoplasm; centrosome; spindle;
Biological process	protein K11-linked ubiquitination; regulation of mitotic nuclear division; anaphase-promoting complex-dependent catabolic process; cell population proliferation; protein ubiquitination; cell division; cell cycle; mitotic cell cycle; regulation of mitotic cell cycle phase transition; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	8881
	69957
	ENSG00000130177
	ENSMUSG00000038416
	Q13042
	Q8R349
NM_001078645; NM_003903; NM_001318517; NM_001318518; NM_001330101;
	NM_001330104; NM_001330105
	NM_027276; NM_001357247
NP_001072113; NP_001305446; NP_001305447; NP_001317030; NP_001317033;
	NP_001317034; NP_003894
	NP_081552; NP_001344176
	Wikidata
View/Edit Human	View/Edit Mouse

Cell division cycle protein 16 homolog is a protein that in humans is encoded by the CDC16 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000130177 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038416 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tugendreich S, Tomkiel J, Earnshaw W, Hieter P (Apr 1995). "CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition". Cell. 81 (2): 261–8. doi:10.1016/0092-8674(95)90336-4. PMID 7736578. S2CID 17907584.
^ "Entrez Gene: CDC16 cell division cycle 16 homolog (S. cerevisiae)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000130177 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038416 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7736578-5] Tugendreich S, Tomkiel J, Earnshaw W, Hieter P (Apr 1995). "CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition". Cell. 81 (2): 261–8. doi:10.1016/0092-8674(95)90336-4. PMID 7736578. S2CID 17907584.

[entrez-6] "Entrez Gene: CDC16 cell division cycle 16 homolog (S. cerevisiae)".

CDC16 information

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CDC16

TBC domain

TBC

Tetratricopeptide repeat

TBC1D1

TBC1D12

Marc Kirschner

ANAPC5

EVI5L

CDC27

CDC20

RABGAP1

Induced cell cycle arrest

PRP36

TBC1D24

RAB40A

SGSM2

PPP5C

USP6

CUL4A