Global Information Lookup Global Information

Succinimide information


Succinimide
Skeletal formula of succinimide
Ball-and-stick model of the succinimide molecule
Names
Preferred IUPAC name
Pyrrolidine-2,5-dione[1]
Other names
Succinimide
Succinic acid imide
Identifiers
CAS Number
  • 123-56-8 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:9307 ☒N
ChEMBL
  • ChEMBL275661 checkY
ChemSpider
  • 10955 checkY
ECHA InfoCard 100.004.215 Edit this at Wikidata
PubChem CID
  • 11439
RTECS number
  • WN2200000
UNII
  • 10X90O3503 checkY
CompTox Dashboard (EPA)
  • DTXSID8051629 Edit this at Wikidata
InChI
  • InChI=1S/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7) checkY
    Key: KZNICNPSHKQLFF-UHFFFAOYSA-N checkY
  • InChI=1/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)
    Key: KZNICNPSHKQLFF-UHFFFAOYAV
SMILES
  • O=C1NC(=O)CC1
Properties[2]
Chemical formula
C4H5NO2
Molar mass 99.089 g·mol−1
Appearance White crystalline powder
Density 1.41 g/cm3
Melting point 125 to 127 °C (257 to 261 °F; 398 to 400 K)
Boiling point 287 to 289 °C (549 to 552 °F; 560 to 562 K)
Solubility in water
0.33 g/mL
Acidity (pKa) 9.5
Magnetic susceptibility (χ)
-47.3·10−6 cm3/mol
Pharmacology
ATC code
G04BX10 (WHO)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Irritant
Slightly Flammable
Lethal dose or concentration (LD, LC):
LD50 (median dose)
14 g/kg (rat, oral)[2]
Safety data sheet (SDS) External MSDS
Related compounds
Related Imides
Maleimide, N-Chlorosuccinimide, N-Bromosuccinimide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Succinimide is an organic compound with the formula (CH2)2(CO)2NH. This white solid is used in a variety of organic syntheses, as well as in some industrial silver plating processes. The compound is classified as a cyclic imide. It may be prepared by thermal decomposition of ammonium succinate.[4]

  1. ^ International Union of Pure and Applied Chemistry (2014). Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013. The Royal Society of Chemistry. p. 869. doi:10.1039/9781849733069. ISBN 978-0-85404-182-4.
  2. ^ a b Merck Index, 12th Edition, 9040
  3. ^ Record of Succinimide in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 10 December 2021.
  4. ^ H. T. Clarke and Letha Davies Behr "Succinimide" Organic Syntheses 1936, volume 16, 75. doi:10.15227/orgsyn.016.0075.

and 25 Related for: Succinimide information

Request time (Page generated in 0.526 seconds.)

Succinimide

Last Update:

Succinimide is an organic compound with the formula (CH2)2(CO)2NH. This white solid is used in a variety of organic syntheses, as well as in some industrial...

Word Count : 225

Sacubitril

Last Update:

the epoxide. A Mitsunobu reaction with succinimide is performed, followed by acidic hydrolysis of the succinimide protecting group, hydrolysis of the alkyl...

Word Count : 526

Deamidation

Last Update:

peptide group (in black at top right of Figure), forming an asymmetric succinimide intermediate (in red). The asymmetry of the intermediate results in two...

Word Count : 995

Ethosuximide

Last Update:

adverse effects on the fetus during pregnancy. Ethosuximide is in the succinimide family of medications. Its mechanism of action is thought to be due to...

Word Count : 1818

Phensuximide

Last Update:

Phensuximide is an anticonvulsant in the succinimide class. Diseases Database (DDB): 31648 Rankin G, Cressey-Veneziano K, Wang R, Brown P (1986). "Urinary...

Word Count : 54

Isoaspartate

Last Update:

the side chain of an asparagine or aspartic acid residue, forming a succinimide intermediate (in red). Hydrolysis of the intermediate results in two...

Word Count : 419

Mesuximide

Last Update:

Mesuximide (or methsuximide, methosuximide) is a succinimide anticonvulsant medication. It is sold as a racemate by Pfizer under the tradenames Petinutin...

Word Count : 152

Acalypha indica

Last Update:

nicotiflorin, and biorobin. Tannins, β-sitosterol, acalyphamide, aurantiamide, succinimide, and flindersin (a pyranoquinolinone alkaloid) have also been isolated...

Word Count : 1064

Phenylpiracetam

Last Update:

Methylphenylpiracetam, a methylated analog Phenylpiracetam hydrazide Phensuximide, a succinimide analog Racetams Phenibut, also included in cosmonaut medical kits "WHO...

Word Count : 1325

Anticonvulsant

Last Update:

(2016). Etiracetam. Levetiracetam (1999). Seletracetam. The following are succinimides: Ethosuximide (1955). Phensuximide. Mesuximide. Acetazolamide (1953)...

Word Count : 5787

Diroximel fumarate

Last Update:

in monomethyl fumarate (MMF), the active metabolite, and hydroxyethyl succinimide (HES), which is inactive. Diroximel fumarate itself is not present in...

Word Count : 1020

Protein primary structure

Last Update:

be blocked with certain inhibitors, such as tunicamycin. deamidation (succinimide formation) In this modification, an asparagine or aspartate side chain...

Word Count : 2595

Detergent

Last Update:

amines and amides such as polyisobuteneamine and polyisobuteneamide/succinimide. Reagent grade detergents are employed for the isolation and purification...

Word Count : 2175

Functional group

Last Update:

aldimine RC(=NR')H imino- -imine Imide Imide (RCO)2NR' imido- -imide Succinimide (Pyrrolidine-2,5-dione) Azide Azide RN3 azido- alkyl azide Phenyl azide...

Word Count : 1212

Imide

Last Update:

dicarboxylic acids, and their names reflect the parent acid. Examples are succinimide, derived from succinic acid, and phthalimide, derived from phthalic acid...

Word Count : 873

List of gasoline additives

Last Update:

mainly used with methanol racing fuel Butyl rubber (as polyisobutylene succinimide, detergent to prevent fouling of diesel fuel injectors) Ferrous picrate...

Word Count : 712

Trastuzumab emtansine

Last Update:

reagent that contains two reactive functional groups, a succinimide ester and a maleimide. The succinimide group of SMCC reacts with the free amino group of...

Word Count : 2699

Polyaspartic acid

Last Update:

a poly(succinimide). The resulting polymer reacts with aqueous sodium hydroxide, which hydrolyzes one of the two amide bonds of the succinimide ring to...

Word Count : 1724

BODIPY

Last Update:

positions of the cyclic core can be displaced by halogen atoms using succinimide reagents such as NCS, NBS and NIS - which allows for further post-functionalisation...

Word Count : 1940

Imine

Last Update:

double and single bonds can be correlated with imides and amides, as in succinimide vs acetamide. Imines are related to ketones and aldehydes by replacement...

Word Count : 2633

Maleimide

Last Update:

carbon fiber thermoset polymer matrix composites. N-Methylmaleimide Succinimide Hermanson G (2013). "Chapter 6: Heterobifunctional Crosslinkers". Bioconjugate...

Word Count : 1741

ATC code N03

Last Update:

ATC code N03 Antiepileptics is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed...

Word Count : 275

Succinic acid

Last Update:

anhydride. Succinate can be used to derive 1,4-butanediol, maleic anhydride, succinimide, 2-pyrrolidinone and tetrahydrofuran. In 2004, succinate was placed on...

Word Count : 4511

Hydroboration

Last Update:

iodine. Such reactions have not however proven very popular, because succinimide based reagents such as NIS and NBS are more versatile and do not require...

Word Count : 1800

Sunepitron

Last Update:

that product with succinic anhydride converts the pendant amine to a succinimide, affording the anxiolytic agent sunepitron (1). Lesopitron Goodnick PJ...

Word Count : 301

PDF Search Engine © AllGlobal.net