Sacubitril (/səˈkjuːbɪtrɪl/; INN) is an antihypertensive drug used in combination with valsartan. The combination drug sacubitril/valsartan, known during trials as LCZ696 and marketed under the brand name Entresto, is a treatment for heart failure.[1] It was approved under the FDA's priority review process for use in heart failure on July 7, 2015.
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Sacubitril (/səˈkjuːbɪtrɪl/; INN) is an antihypertensive drug used in combination with valsartan. The combination drug sacubitril/valsartan, known during...
valsartan/amlodipine/hydrochlorothiazide, valsartan/nebivolol, and valsartan/sacubitril. Valsartan is used to treat high blood pressure, heart failure, and to...
heart failure. Sacubitril/valsartan (Entresto/LCZ696), which has been tested against enalapril in patients with heart failure. Sacubitril (AHU-377), a prodrug...
(NEP). Recently, NEP inhibitors have been developed, such as Sacubitril and Sacubitril/valsartan. They may be clinically useful in treating patients...
(INN; or LBQ657) is the active metabolite of the antihypertensive drug sacubitril, which is used in the treatment of heart failure. Solomon SD. "HFpEF in...
heart failure. The angiotensin receptor-neprilysin inhibitors (ARNI) sacubitril/valsartan is recommended as first choice of RAS inhibitors in American...
ecadotril; prodrug to thiorphan Sacubitril - prodrug to sacubitrilat Sacubitrilat - active metabolite of sacubitril Thiorphan - active metabolite of...
Olmesartan medoxomil, amlodipine and hydrochlorothiazide C09DX04 Valsartan and sacubitril C09DX05 Valsartan and nebivolol C09DX06 Candesartan, amlodipine and hydrochlorothiazide...
co-PI of the PARADIGM-HF trial that led to the approval of valsartan/sacubitril. The PROFILE trial had negative results; it was terminated early in 1993...
inhibitors. This drug can cause diarrhea, muscle cramps, and dizziness. Sacubitril/valsartan (Entresto)- Type of Drug that combines ARBs with another medicinal...