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Sodium chloroacetate information


Sodium chloroacetate
Names
Preferred IUPAC name
Sodium chloroacetate
Other names
sodium monochloroacetate
Identifiers
CAS Number
  • 3926-62-3 checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 56306 ☒N
ECHA InfoCard 100.021.363 Edit this at Wikidata
PubChem CID
  • 23665759
UNII
  • 8D9PZU6L69 checkY
CompTox Dashboard (EPA)
  • DTXSID1027550 Edit this at Wikidata
InChI
  • InChI=1S/C2H3ClO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1 ☒N
    Key: FDRCDNZGSXJAFP-UHFFFAOYSA-M ☒N
  • InChI=1/C2H3ClO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
    Key: FDRCDNZGSXJAFP-REWHXWOFAF
SMILES
  • C(C(=O)[O-])Cl.[Na+]
Properties
Chemical formula
C2H2ClNaO2
Molar mass 116.48 g·mol−1
Appearance white solid
Density 1.401 g/cm3 (25 °C)
Solubility in water
soluble in water, ethanol, chloroform, ether and benzene
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
irritant to skin
Autoignition
temperature
does not ignite
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Sodium chloroacetate is the organic compound with the formula CH2ClCO2Na. A white, water-soluble solid, it is the sodium salt of chloroacetic acid. Many of its uses are similar to those of the parent acid. It is prepared by treating chloroacetic acid with sodium carbonate.[1][2]

  1. ^ Koenig, Günter; Lohmar, Elmar; Rupprich, Norbert (2000). "Chloroacetic Acids". Ullmann's Encyclopedia of Industrial Chemistry. doi:10.1002/14356007.a06_537. ISBN 3527306730.
  2. ^ Nathan Weiner (1938). "Malonic Acid". Organic Syntheses. 18: 50. doi:10.15227/orgsyn.018.0050.

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Sodium chloroacetate

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Sodium chloroacetate is the organic compound with the formula CH2ClCO2Na. A white, water-soluble solid, it is the sodium salt of chloroacetic acid. Many...

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Sodium fluoroacetate

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brand name. The salt is synthesized by treating sodium chloroacetate with potassium fluoride. Both sodium and potassium salts are derivatives of fluoroacetic...

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Ethyl chloroacetate

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as sodium fluoroacetate). An example for the use of this agent was in the synthesis of cinepazet. Synthesis of Fenmetramide. Ethyl chloroacetate at Sigma-Aldrich...

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Nitromethane

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other methods that are of instructional value. The reaction of sodium chloroacetate with sodium nitrite in aqueous solution produces this compound: ClCH2COONa...

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Chloroacetic acid

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2-Chloropropionic acid 3-Chloropropanoic acid 2,2-Dichloropropionic acid Sodium chloroacetate Except where otherwise noted, data are given for materials in their...

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Sodium lauroamphoacetate

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equivalent of sodium chloroacetate to give the final product. A reaction with 2 equivalents gives the di-acetate, which is also marketed as di-sodium lauroamphoacetate...

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Sodium trichloroacetate

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acyl halides. Trichloroacetic acid Sodium trifluoroacetate Sodium chloroacetate Murray, M. G. (1986). "Use of sodium trichloroacetate and mung bean nuclease...

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Nitro compound

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Nitromethane can be produced in the laboratory by treating sodium chloroacetate with sodium nitrite. Oxidation of oximes or primary amines. Reduction of...

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Thioglycolic acid

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thioglycolate. Thioglycolic acid is prepared by reaction of sodium or potassium chloroacetate with alkali metal hydrosulfide in aqueous medium. It can be...

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Diethyl malonate

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C2H5OH + 2 HCl → C2H5O2CCH2CO2C2H5 + NH4Cl + NaCl Alternatively, sodium chloroacetate undergoes carboxyesterification by treatment with carbon monoxide...

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Polyglycolide

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Polycondensation is carried out by heating an halogenoacetate, like sodium chloroacetate, at a temperature between 160 and 180 °C, continuously passing nitrogen...

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Cocamidopropyl betaine

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sensitization reactions. These by-products can be avoided by a moderate excess chloroacetate and the exact adjustment of pH value during betainization reaction accompanied...

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Chloroacetic acids

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the citric acid cycle) that normally process plain acetate ions. The chloroacetate anion is the most toxic, with a rat, oral LD50 of about 0.5 g/kg. "Ionization...

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Phendimetrazine

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reaction between Ephedrine [299-42-3] (1) and ethyl chloroacetate [105-39-5] (2) in the presence of sodium hydride gives 4,5-dimethyl-6-phenylmorpholin-3-one...

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Ethyl cyanoacetate

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prepared via Kolbe nitrile synthesis using sodium chloroacetate and sodium cyanide. Reaction of the sodium cyanoacetate with ethyl bromide in an aqueous–organic...

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Phenoxyacetic acid

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monocarboxylic acid and an aryl ether. Its preparation from sodium phenolate and sodium chloroacetate in hot water was first reported in 1880. 1) C6H5O−Na+...

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List of additives used for fracking

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Sodium chloroacetate 68-04-2 Sodium citrate 6381-77-7 Sodium erythorbate / isoascorbic acid, sodium salt 2836-32-0 Sodium Glycolate 1310-73-2 Sodium Hydroxide...

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List of UN numbers 2601 to 2700

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no longer in use) Selenium (UN No. no longer in use) UN 2659 6.1 Sodium chloroacetate UN 2660 6.1 Nitrotoluidines (mono) UN 2661 6.1 Hexachloroacetone...

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Cyanoacetic acid

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of adhesives. Cyanoacetic acid is prepared by treatment of chloroacetate salts with sodium cyanide followed by acidification. Electrosynthesis by cathodic...

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Lorajmine

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alkaloid from the roots of Rauvolfia serpentina, by synthetically adding a chloroacetate residue. Medical Dictionary Online: Lorajmine World Health Organization:...

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List of viscosities

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Refractive Index, and Speed of Sound in the Binary Mixtures of Ethyl Chloroacetate + Cyclohexanone, + Chlorobenzene, + Bromobenzene, or + Benzyl Alcohol...

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Reformatsky reaction

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1002/cber.188702001268. Reformatsky, S. (1890). "Action of zinc and ethyl chloroacetate on ketones and aldehydes". J. Russ. Phys. Chem. Soc. 22: 44. Shriner...

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Brodifacoum

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obtain this starting Compound 1, a simple Wittig condensation of ethyl chloroacetate with 4’-bromobiphenylcarboxaldehyde is accomplished. Compound 1 is transformed...

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List of compounds with carbon number 4

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141-75-3 C4H7ClO2 ethoxyacetyl chloride 500025-15-0 C4H7ClO2 ethyl chloroacetate 105-39-5 C4H7CsO2 caesium butyrate 38869-25-9 C4H7FO2 isopropyl fluoromethanoate...

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Methyl fluoroacetate

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with silver fluoride. It can also be synthesized by reacting methyl chloroacetate with potassium fluoride Because of its toxicity, MFA was studied for...

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Neodymium compounds

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ammonium bicarbonate in water or from the hydrolysis of neodymium(III) chloroacetate: 2Nd(C2Cl3O2)3 + 3H2O → Nd2(CO3)3 + 6CHCl3 + 3CO2 Neodymium(III) acetate...

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List of UN numbers 2901 to 3000

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2-Amino-5-diethylaminopentane UN 2947 3 Isopropyl chloroacetate UN 2948 6.1 3-Trifluoromethylaniline UN 2949 8 Sodium hydrosulfide, with not less than 25 percent...

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List of UN numbers 2501 to 2600

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Pesticides, solid, toxic, not otherwise specified UN 2589 6.1 Vinyl chloroacetate UN 2590 9 White asbestos (chrysotile, actinolite, anthophyllite, tremolite)...

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