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Chemical compound
Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison. In recent years, it has become one of the world's most widely used pesticides. It is typically used as a rodenticide, but is also used to control larger pests such as possums.[2]
Brodifacoum has an especially long half-life in the body, which ranges up to nine months, requiring prolonged treatment with antidotal vitamin K for both human and pet poisonings. It has one of the highest risks of secondary poisoning to both mammals and birds.[3] Significant experience in brodifacoum poisonings has been gained in many human cases where it has been used in attempted suicides, necessitating long periods of vitamin K treatment. In March 2018, cases of severe coagulopathy and bleeding associated with synthetic cannabinoid use contaminated with brodifacoum were reported in five states of the US.
^Merck Index, 11th Edition, 1368
^Eason, C.T. and Wickstrom, M. Vertebrate pesticide toxicology manual, New Zealand Department of Conservation
^Rodenticides: Topic Fact Sheet, National Pesticide Information Center
Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison. In recent years, it has become one of the world's most widely...
strains of rodents, though some second generation anticoagulants (namely brodifacoum and difethialone), in bait concentrations of 0.0025% to 0.005% are so...
pest rodents from islands using an anticoagulant rodenticide such as brodifacoum. This approach has been successful on the island of Lundy in the United...
Norway Rats (rattus Norvegicus) from Hawea Island, Fiordland, Using Brodifacoum". New Zealand Journal of Ecology. 12: 23–32. ISSN 0110-6465. JSTOR 24053177...
ISBN 978-0-12-369442-3. "Bufotoxin". ChemIDplus. U.S. National Library of Medicine. "Brodifacoum (PDS)". Inchem.org. Archived from the original on 2013-12-13. Retrieved...
rotated to avoid populations becoming bait-shy or building up resistance. Brodifacoum is a second-generation anticoagulant. It is licensed for killing possums...
coumarin are also called coumarins or coumarinoids; this family includes: brodifacoum bromadiolone difenacoum auraptene ensaculin phenprocoumon (Marcoumar)...
risks from synthetic cannabinoid products that contain the rat poison brodifacoum, which is added because it is thought to extend the duration of the drugs'...
months in cases of poisoning by "superwarfarin" rodenticides such as brodifacoum. Oral vitamin K1 is preferred over other vitamin K1 routes of administration...
phenprocoumon, atromentin, and phenindione.[citation needed] The coumarins brodifacoum and difenacoum are used as mammalicides (particularly as rodenticides)...
the insecticides pirimiphos-methyl in 1967 and pirimicarb in 1970, brodifacoum (a rodenticide) was developed in 1974; in the late 1970s, ICI was involved...
(Coumadin) Coumatetralyl Phenprocoumon Acenocoumarol Dicoumarol Tioclomarol Brodifacoum Another group of VKAs are 1,3-indandione derivatives. Pindone, chlorophacinone...
superwarfarins because they are much more potent and long acting than warfarin. Brodifacoum Bromadiolone Difenacoum Flocoumafen Feinstein, D. L; Akpa, B. S; Ayee...
took place in May that year, was announced. 180 tonnes of rat poison, brodifacoum, were dropped over 70% of the island, in what was the world's largest...
substituent at the 3 position of the coumarin. Vitamin K1 is used as antidote. Brodifacoum "40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances...
residue analysis during systematic searches or as nontarget mortalities. Brodifacoum residues (the toxicant employed during the project) were detected in...
Other 4-hydroxycoumarins used as rodenticides include coumatetralyl and brodifacoum, which is sometimes referred to as "super-warfarin", because it is more...
of prey TALON (database), a database maintained by the US Air Force Brodifacoum, a rodenticide, also known as the brand Talon an anti-vehicle-ramming...
Anticoagulant Hydroxycoumarin Rodenticide High Single Moderate Highest Brodifacoum Anticoagulant Hydroxycoumarin Rodenticide Highest Single Highest Highest...
control on islands infested with invasive rat populations. Bait, such as brodifacoum, is also used along with coloured dyes (used to deter birds from eating...
programme used helicopters to drop cereal pellets containing the rodenticide brodifacoum. Gough has also been identified as the third-most important island in...
levels of brodifacoum in 12 of the 16 carcasses tested. Of the 320 glaucous-winged gull carcasses collected, toxicology tests implicated brodifacoum in 24...
(1988). "Potential hazard to eastern screech-owls and other raptors of brodifacoum bait used for vole control in orchards". Environmental Toxicology and...
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