This article is missing information about overall structure (as context for "S domain" pics and for mechanism description); rough structure and function of binding proteins. Please expand the article to include this information. Further details may exist on the talk page.(October 2021)
signal recognition particle 9kDa
Identifiers
Symbol
SRP9
NCBI gene
6726
HGNC
11304
OMIM
600707
RefSeq
NM_003133
UniProt
P49458
Other data
Locus
Chr. 1 q42.12
Search for
Structures
Swiss-model
Domains
InterPro
signal recognition particle 14kDa
Identifiers
Symbol
SRP14
NCBI gene
6727
HGNC
11299
OMIM
600708
RefSeq
NM_003134
UniProt
P37108
Other data
Locus
Chr. 15 q22
Search for
Structures
Swiss-model
Domains
InterPro
signal recognition particle 19kDa
Identifiers
Symbol
SRP19
NCBI gene
6728
HGNC
11300
OMIM
182175
RefSeq
NM_003135
UniProt
P09132
Other data
Locus
Chr. 5 q21-q22
Search for
Structures
Swiss-model
Domains
InterPro
signal recognition particle 54kDa
Identifiers
Symbol
SRP54
NCBI gene
6729
HGNC
11301
OMIM
604857
RefSeq
NM_003136
UniProt
P61011
Other data
Locus
Chr. 14 q13.2
Search for
Structures
Swiss-model
Domains
InterPro
signal recognition particle 68kDa
Identifiers
Symbol
SRP68
NCBI gene
6730
HGNC
11302
OMIM
604858
RefSeq
NM_014230
UniProt
Q9UHB9
Other data
Locus
Chr. 17 q25.1
Search for
Structures
Swiss-model
Domains
InterPro
signal recognition particle 72kDa
Identifiers
Symbol
SRP72
NCBI gene
6731
HGNC
11303
OMIM
602122
RefSeq
NM_006947
UniProt
O76094
Other data
Locus
Chr. 4 q11
Search for
Structures
Swiss-model
Domains
InterPro
Signal recognition particle protein
Identifiers
Organism
Escherichia coli (strain K12)
Symbol
ffh
Alt. symbols
p48, Srp54
UniProt
P0AGD7
Search for
Structures
Swiss-model
Domains
InterPro
The signal recognition particle (SRP) is an abundant, cytosolic, universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets specific proteins to the endoplasmic reticulum in eukaryotes and the plasma membrane in prokaryotes.[1]
^Tisdale S, Pellizzoni L (2017-01-01). "Chapter 7 - RNA-Processing Dysfunction in Spinal Muscular Atrophy". In Sumner CJ, Paushkin S, KO CP (eds.). Spinal Muscular Atrophy. Academic Press. pp. 113–131. doi:10.1016/b978-0-12-803685-3.00007-0. ISBN 978-0-12-803685-3.
and 27 Related for: Signal recognition particle information
The signalrecognitionparticle (SRP) is an abundant, cytosolic, universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets...
The signalrecognitionparticle RNA, (also known as 7SL, 6S, ffs, or 4.5S RNA) is part of the signalrecognitionparticle (SRP) ribonucleoprotein complex...
Signalrecognitionparticle (SRP) receptor, also called the docking protein, is a dimer composed of 2 different subunits that are associated exclusively...
Signalrecognitionparticle 9 is a protein that in humans is encoded by the SRP9 gene. GRCh38: Ensembl release 89: ENSG00000143742 – Ensembl, May 2017...
pathway is initiated when the signal peptide emerges from the ribosome and is recognized by the signal-recognitionparticle (SRP). SRP then halts further...
Inflammatory myopathy, also known as idiopathic inflammatory myopathy (IIM), is disease featuring muscle weakness, inflammation of muscles (myositis),...
derived from the small cytoplasmic 7SL RNA, a component of the signalrecognitionparticle. Alu elements are highly conserved within primate genomes and...
Lacomis, D.; Lucas, M.; Fertig, N.; Oddis, C. V. (2004). "Anti-signalrecognitionparticle autoantibody in patients with and patients without idiopathic...
reticulum are handled by the signalrecognitionparticle which is bound to the ribosomal exit tunnel and initiates recognition and shielding as protein is...
Signalrecognitionparticle receptor subunit beta is a protein that in humans is encoded by the SRPRB gene. The protein encoded by this gene has similarity...
SRP may refer to: Scaling and root planing, in dentistry Signalrecognitionparticle, in cell biology Spreading resistance profiling, for measuring semiconductor...
ribosomes. The nucleolus also participates in the formation of signalrecognitionparticles and plays a role in the cell's response to stress. Nucleoli are...
class of GTPases is activated by dimerization. Named after the signalrecognitionparticle (SRP), MinD, and BioD, the class is involved in protein localization...
antibodies against histidine—tRNA ligase (Anti-Jo1); antibodies to signalrecognitionparticle (SRP); and anti-Mi-2 antibodies. Magnetic resonance imaging may...
acids polymerized encode a signal peptide, a molecular message that is recognized and bound by a signalrecognitionparticle (SRP). Translation pauses...
essential for the complex's function. He also named the complex signalrecognitionparticle (SRP). By the time Walter joined the University of California...
of the endoplasmic reticulum signalrecognitionparticle receptor that, in conjunction with the signalrecognitionparticle, is involved in the targeting...
This sequence is recognised by a cytosolic protein, SRP (Signal RecognitionParticle), which stops the translation and aids in the transport of the mRNA-ribosome...
being synthesized on the ribosome, when a signalrecognitionparticle (SRP) recognizes an N-terminal signal peptide of the nascent protein. Binding of...
RNase P and RNase MRP RNA 7SL RNA (the RNA component of the signalrecognitionparticle) Vault RNAs Y RNA SINEs (short interspersed repetitive elements)...
translocated to the endoplasmic reticulum are recognized by the signal-recognitionparticle (SRP), which halts translation of the polypeptide by the ribosome...
elements. The rest are related to ribosomal, spliceosomal and signalrecognitionparticle RNA. The mitochondrial genome of the genus Sphenodon is approximately...
Some other proteins are inserted into the membrane via the SRP (signalrecognitionparticle) pathway. The chloroplast SRP can interact with its target proteins...
protein All organisms Ribosomal RNA rRNA Translation All organisms Signalrecognitionparticle RNA 7SL RNA or SRP RNA Membrane integration All organisms Transfer...
Global Information