Under United States law, Biological select agents or toxins (BSATs)—or simply select agents for short—are bio-agents which (since 1997[1]) have been declared by the U.S. Department of Health and Human Services (HHS) or by the U.S. Department of Agriculture (USDA) to have the "potential to pose a severe threat to public health and safety". The agents are divided into (1) HHS select agents and toxins affecting humans; (2) USDA select agents and toxins affecting agriculture; and (3) overlap select agents and toxins affecting both.
The U.S. Centers for Disease Control and Prevention (CDC) regulates the laboratories which may possess, use, or transfer select agents within the United States in its Select Agent Program (SAP)—also called the Federal Select Agent Program (FSAP)—since 2001. The SAP was established to satisfy requirements of the USA PATRIOT Act of 2001 and the Public Health Security and Bioterrorism Preparedness and Response Act of 2002, which were enacted in the wake of the September 11, 2001 attacks and the subsequent 2001 anthrax attacks.
Using BSATs in biomedical research prompts concerns about dual use. The federal government created the National Science Advisory Board for Biosecurity which promotes biosecurity in life science research. It is composed of government, education and industry experts who provide policy recommendations on ways to minimize the possibility that knowledge and technologies emanating from biological research will be misused to threaten public health or national security.
^Additional Requirements for Facilities Transferring or Receiving Select Agents, Title 42 CFR Part 72 and Appendix A; 15 April 1997 (DHHS).
Under United States law, Biological selectagents or toxins (BSATs)—or simply selectagents for short—are bio-agents which (since 1997) have been declared...
defined as "selectagents" and possession or transportation of them are tightly controlled as such. Selectagents are divided into "HHS selectagents and toxins"...
9 CFR Subchapter B. Not all selectagents require BSL-4 handling, namely select bacteria and toxins, but most selectagent viruses do (with the notable...
documented deaths. Until October 2012, C. immitis had been listed as a selectagent by both the U.S. Department of Health and Human Services and the U.S...
and nonhuman primates, a form of viral hemorrhagic fever. RAVV is a Selectagent, World Health Organization Risk Group 4 Pathogen (requiring Biosafety...
original (PDF) on 17 January 2009. "Permissible Toxin Amounts". National SelectAgent Registry. 10 September 2020. "40 C.F.R.: Appendix A to Part 355 – The...
tested toxic agents, flamethrowers, chemical spray systems, biological warfare weapons, fire bombing tactics, antidotes for chemical agents, and protective...
with treatment. The CDC classifies it as a "Tier 1 selectagent" with potential as a bioterrorism agent. It infects other animals, most commonly livestock...
can be found in the seeds of Abrus pulchellus. Abrin is classed as a "selectagent" under U.S. law. Abrin is formed in nature by only the rosary pea. The...
F. tularensis is classified as a Tier 1 SelectAgent by the U.S. government, along with other potential agents of bioterrorism such as Yersinia pestis...
of select biological agents outside of the primary barriers of the biocontainment in the US were described by the annual report of the Federal Select Agent...
viral hemorrhagic fevers. All filoviruses are classified by the US as selectagents, by the World Health Organization as Risk Group 4 Pathogens (requiring...
user of biological agents] must develop and implement a written biosafety plan that is commensurate with the risk of the selectagent or toxin" which is...
2009. Retrieved 17 March 2013. "Permissible Toxin Amounts". Federal SelectAgent Program. United States Centers for Disease Control and Prevention. Retrieved...
farm animals. The US Health and Human Services agency considers it a selectagent for research purposes. Hoerr FJ, Carlton WW, Yagen B (1981). "Mycotoxicosis...
incorporating security controls into an information system Selectagent – Controlled biological agents in the United States Citations "Biorisk management: Laboratory...
high fatality rate (up to 83 to 90 percent), EBOV is also listed as a selectagent, World Health Organization Risk Group 4 Pathogen (requiring Biosafety...
and other primates. Lassa mammarenavirus is an emerging virus and a selectagent, requiring Biosafety Level 4-equivalent containment. It is endemic in...
any franchise. Undrafted free agents Undrafted free agents are players eligible for the NFL Draft but were not selected; they can negotiate and sign with...
file-select control, there is some variation among web browsers. Typically, on a Windows-based platform, user agents will render a file-select control...
engineered systems provide acceptable levels of safety Selectagent – Controlled biological agents in the United States s:Outer Space Treaty of 1967#Article...
stockpile of biological agents and weapons. Over the course of its 27-year history, the program weaponized and stockpiled seven bio-agents — Bacillus anthracis...
and nonhuman primates, a form of viral hemorrhagic fever. Both are selectagents, World Health Organization Risk Group 4 Pathogens (requiring Biosafety...
In intelligence and artificial intelligence, an intelligent agent (IA) is an agent acting in an intelligent manner; It perceives its environment, takes...
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