Project that developed a haplotype map of the human genome
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The International HapMap Project was an organization that aimed to develop a haplotype map (HapMap) of the human genome, to describe the common patterns of human genetic variation. HapMap is used to find genetic variants affecting health, disease and responses to drugs and environmental factors. The information produced by the project is made freely available for research.
The International HapMap Project is a collaboration among researchers at academic centers, non-profit biomedical research groups and private companies in Canada, China (including Hong Kong), Japan, Nigeria, the United Kingdom, and the United States. It officially started with a meeting on October 27 to 29, 2002, and was expected to take about three years. It comprises two phases; the complete data obtained in Phase I were published on 27 October 2005.[1] The analysis of the Phase II dataset was published in October 2007.[2] The Phase III dataset was released in spring 2009 and the publication presenting the final results published in September 2010.[3]
^Altshuler, David; Donnelly, Peter; The International HapMap Consortium (October 2005). "A haplotype map of the human genome". Nature. 437 (7063): 1299–1320. Bibcode:2005Natur.437.1299T. doi:10.1038/nature04226. ISSN 1476-4687. PMC 1880871. PMID 16255080.
^Frazer, Kelly A.; Ballinger, Dennis G.; Cox, David R.; Hinds, David A.; Stuve, Laura L.; Gibbs, Richard A.; Belmont, John W.; Boudreau, Andrew; Hardenbol, Paul; Leal, Suzanne M.; Pasternak, Shiran (October 2007). "A second generation human haplotype map of over 3.1 million SNPs". Nature. 449 (7164): 851–861. Bibcode:2007Natur.449..851F. doi:10.1038/nature06258. hdl:2027.42/62863. ISSN 1476-4687. PMC 2689609. PMID 17943122.
^Altshuler, David M.; Gibbs, Richard A.; Peltonen, Leena; Altshuler, David M.; Gibbs, Richard A.; Peltonen, Leena; Dermitzakis, Emmanouil; Schaffner, Stephen F.; Yu, Fuli; Peltonen, Leena; Dermitzakis, Emmanouil (September 2010). "Integrating common and rare genetic variation in diverse human populations". Nature. 467 (7311): 52–58. Bibcode:2010Natur.467...52T. doi:10.1038/nature09298. ISSN 1476-4687. PMC 3173859. PMID 20811451.
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the InternationalHapMapProject, whose goal was to identify patterns of single-nucleotide polymorphism (SNP) groups (called haplotypes, or "haps"). The...
website Gibbs, Richard A.; et al. (The InternationalHapMap Consortium) (2003). "The InternationalHapMapProject" (PDF). Nature. 426 (6968): 789–796. Bibcode:2003Natur...
a contributing member of the InternationalHapMapProject, an organization that worked to develop the first haplotype map of the human genome. He is the...
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targets and polymorphisms within the human race. In fact, the InternationalHapMapproject was created through a partnership of scientists and agencies...
Cavalli-Sforza (1994) for some populations: A 2012 study based on InternationalHapMapProject data estimated FST between the three major "continental" populations...
Devlin & Risch The InternationalHapMapProject enables the study of LD in human populations online. The Ensembl project integrates HapMap data with other...
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affecting lactase persistence, and adaptation to high altitude. InternationalHapMapProject Hill-Robertson effect Soft selective sweep Smith, John Maynard;...
InternationalHapMapProject as well as many large national projects. She has also been an active member of the steering committee for international research...
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