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Replication timing information


Figure 1: Schematic of the cell cycle. outer ring: I = Interphase, M = Mitosis; inner ring: M = Mitosis, G1 = Gap 1, G2 = Gap 2, S = Synthesis; not in ring: G0 = Gap 0/Resting.

Replication timing refers to the order in which segments of DNA along the length of a chromosome are duplicated.

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Replication timing

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segments replicate in one type of human cell. The temporal order of replication of all the segments in the genome, called its replication-timing program...

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Eukaryotic DNA replication

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Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA...

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Replication timing quantitative trait loci

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Replication timing quantitative trait loci (or rtQTL) are genetic variations that lead to a differential use of replication origins, exhibiting allele-specific...

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Origin of replication

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The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. Propagation of the...

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Topologically associating domain

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between enhancers and their cognate promoters located in the same TAD. Replication timing domains have been shown to be associated with TADs as their boundary...

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Schizosaccharomyces pombe

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asymmetry of the DNA replication process to switch the mating type; it was the first system where the direction of replication was shown to be required...

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Subtelomere

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repressive effects for timing of subtelomeres replication by suppressing Sld3, a replication factor, at the start of the replication. Thus, Sgo2 regulate...

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Replicating portfolio

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(especially cash flows). This is meant in two distinct senses: static replication, where the portfolio has the same cash flows as the reference asset (and...

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Chromosome 2

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44 RFX8: Rfx family member 8, lacking rfx dna binding domain RIF1: replication timing regulatory factor 1 RNU4ATAC: RNA, U4atac small nuclear (U12-dependent...

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Cytogenetics

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reason for these patterns are unknown, although it likely related to replication timing and chromatin packing.[citation needed] Several chromosome-banding...

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S phase

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turn recruits replication protein A (RPA), an ssDNA binding protein. RPA recruitment primes the replication fork for loading of replicative DNA polymerases...

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Mutation

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certain time period in the organism's lifespan. Replication timing quantitative trait loci affects DNA replication. In order to categorize a mutation as such...

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MySQL

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replication: Master to slave replication where the master waits on replication Synchronous replication: Multi-master replication is provided in MySQL Cluster...

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Digital polymerase chain reaction

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Polak P, et al. (November 2014). "Genetic variation in human DNA replication timing". Cell. 159 (5): 1015–1026. doi:10.1016/j.cell.2014.10.025. PMC 4359889...

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ENCODE

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these distal sites show marks consistent with insulator function. DNA replication timing is correlated with chromatin structure. A total of 5% of the bases...

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Inferring horizontal gene transfer

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Deschavanne P, Filipski J (April 1995). "Correlation of GC content with replication timing and repair mechanisms in weakly expressed E.coli genes". Nucleic Acids...

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Midblastula

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state of fast and constant replication of cells. The cell cycle is very short. The cells in the zygote are also replicating synchronously, always undergoing...

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Escherichia coli

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fastest growth rates, replication begins before the previous round of replication has completed, resulting in multiple replication forks along the DNA and...

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Kevin Struhl

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replication, Struhl demonstrated that a histone acetylase (HBO1) is both a transcriptional co-activator and a co-activator for the Cdt1 replication licensing...

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Cruciform DNA

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begin the process of DNA replication. The 14-3-3 proteins dissociate after they assist in the initiation step of DNA replication. The inverted repeat sequences...

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Cell cycle

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beginning of DNA replication. DNA replication occurs during the C period. The D period refers to the stage between the end of DNA replication and the splitting...

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Microchromosome

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mya. Replication timing and recombination rates have been found to differ between micro- and macrochromosomes in chickens. Microchromosomes replicate earlier...

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