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Reflex seizure information


Reflex seizure
SpecialtyNeurology
SymptomsSeizures due to a specific trigger[1]
TreatmentDecreasing exposure to triggers, anti-epileptic medications[2][3]
FrequencyRelatively rare[3]

Reflex seizures are epileptic seizures that are consistently induced by a specific stimulus or trigger, making them distinct from other epileptic seizures, which are usually unprovoked.[4][3] Reflex seizures are otherwise similar to unprovoked seizures and may be focal (simple or complex), generalized, myoclonic, or absence seizures.[1] Epilepsy syndromes characterized by repeated reflex seizures are known as reflex epilepsies.[3][4] Photosensitive seizures are often myoclonic, absence, or focal seizures in the occipital lobe, while musicogenic seizures are associated with focal seizures in the temporal lobe.[3]

Triggers may include various stimuli with the most common (75 to 80%) being flickering lights resulting in photosensitive seizures.[3] Reflex epilepsies are generally thought to be genetic in origin.[3] The inheritance pattern is dependent on the type of reflex epilepsy,with some types lacking specific genetic inheritance patterns.[3] For example, photogenic epilepsy is thought to follow an autosomal dominant pattern with incomplete penetrance, while seizures triggered by proprioceptive stimuli do not follow an observable inheritance pattern.[3] The underlying mechanism involves the stimulation of existing network of neurons by the specific trigger.[3]

The treatment of reflex epilepsy generally involves decreasing exposure to a person's triggers as well as anti-epileptic medications.[2][3] Reflex epilepsy is relatively rare, making up approximately 5% of epilepsy syndromes.[3]

  1. ^ a b Kasteleijn-Nolst Trenité DG (September 2012). "Provoked and reflex seizures: surprising or common?". Epilepsia. 53 (Suppl 4): 105–13. doi:10.1111/j.1528-1167.2012.03620.x. PMID 22946728.
  2. ^ a b Cite error: The named reference Panay2105 was invoked but never defined (see the help page).
  3. ^ a b c d e f g h i j k l Okudan ZV, Özkara Ç (2018-01-18). "Reflex epilepsy: triggers and management strategies". Neuropsychiatric Disease and Treatment. 14: 327–337. doi:10.2147/NDT.S107669. PMC 5779309. PMID 29403278.
  4. ^ a b Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J, Forsgren L, French JA, Glynn M, Hesdorffer DC, Lee BI, Mathern GW, Moshé SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S (April 2014). "ILAE official report: a practical clinical definition of epilepsy" (PDF). Epilepsia. 55 (4): 475–82. doi:10.1111/epi.12550. PMID 24730690. S2CID 35958237.

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