Global InformationMusicogenic seizure information
Musicogenic seizure, also known as music-induced seizure, is a rare type of seizure, with an estimated prevalence of 1 in 10,000,000 individuals, that arises from disorganized or abnormal brain electrical activity when a person hears or is exposed to a specific type of sound or musical stimuli.[1][2] There are challenges when diagnosing a music-induced seizure due to the broad scope of triggers, and time delay between a stimulus and seizure.[3][4] In addition, the causes of musicogenic seizures are not well-established as solely limited cases and research have been discovered and conducted respectively.[1] Nevertheless, the current understanding of the mechanism behind musicogenic seizure is that music triggers the part of the brain that is responsible for evoking an emotion associated with that music.[1] Dysfunction in this system leads to an abnormal release of dopamine, eventually inducing seizure.[5]
Currently, there are diverse intervention strategies that patients can choose from depending on their situations. They can have surgery to remove the region of the brain that generates a seizure.[6] Behavioral therapy is also available; patients are trained to gain emotional control to reduce the frequency of seizure.[1] Medications like carbamazepine and phenytoin (medication for general seizure) also suggest effectiveness to mitigate music-induced seizures.[7]
- ^ a b c d Ellis, Liddy (2017-03-01). "The potential mechanism of musicogenic epilepsy and future research avenues". Bioscience Horizons. 10. doi:10.1093/biohorizons/hzx004. ISSN 1754-7431.
- ^ Sugerman, Deborah Tolmach (2013-09-18). "Seizures". The Journal of the American Medical Association. 310 (11): 1195. doi:10.1001/jama.2013.277840. ISSN 0098-7484. PMID 24045753.
- ^ Kaplan, Peter W.; Stoker, Guy (2010). "2. Musicogenic epilepsy – From sound to seizure". Epilepsy & Behavior. 17 (4): 579. doi:10.1016/j.yebeh.2010.01.027. ISSN 1525-5050. S2CID 54267436.
- ^ Wieser, Heinz Gregor; Hungerbohler, Hansjorg; Siegel, Adrian M.; Buck, Alfred (1997). "Musicogenic Epilepsy: Review of the Literature and Case Report with Ictal Single Photon Emission Computed Tomography". Epilepsia. 38 (2): 200–207. doi:10.1111/j.1528-1157.1997.tb01098.x. ISSN 0013-9580. PMID 9048673.
- ^ Salimpoor, Valorie N; Benovoy, Mitchel; Larcher, Kevin; Dagher, Alain; Zatorre, Robert J (2011). "Anatomically distinct dopamine release during anticipation and experience of peak emotion to music". Nature Neuroscience. 14 (2): 257–262. doi:10.1038/nn.2726. ISSN 1097-6256. PMID 21217764. S2CID 205433454.
- ^ Rohan, Deirdre; Cunningham, Anthony J. (2002). "A Randomized, Controlled Trial of Surgery for Temporal-Lobe Epilepsy". Survey of Anesthesiology. 46 (3): 142–143. doi:10.1097/00132586-200206000-00024. ISSN 0039-6206.
- ^ Nevitt, Sarah J.; Sudell, Maria; Weston, Jennifer; Tudur Smith, Catrin; Marson, Anthony G. (15 December 2017). "Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data". The Cochrane Database of Systematic Reviews. 2017 (12): CD011412. doi:10.1002/14651858.CD011412.pub3. ISSN 1469-493X. PMC 6486134. PMID 29243813.