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Reference range information


In medicine and health-related fields, a reference range or reference interval is the range or the interval of values that is deemed normal for a physiological measurement in healthy persons (for example, the amount of creatinine in the blood, or the partial pressure of oxygen). It is a basis for comparison for a physician or other health professional to interpret a set of test results for a particular patient. Some important reference ranges in medicine are reference ranges for blood tests and reference ranges for urine tests.

The standard definition of a reference range (usually referred to if not otherwise specified) originates in what is most prevalent in a reference group taken from the general (i.e. total) population. This is the general reference range. However, there are also optimal health ranges (ranges that appear to have the optimal health impact) and ranges for particular conditions or statuses (such as pregnancy reference ranges for hormone levels).

Values within the reference range (WRR) are those within normal limits (WNL). The limits are called the upper reference limit (URL) or upper limit of normal (ULN) and the lower reference limit (LRL) or lower limit of normal (LLN). In health care–related publishing, style sheets sometimes prefer the word reference over the word normal to prevent the nontechnical senses of normal from being conflated with the statistical sense. Values outside a reference range are not necessarily pathologic, and they are not necessarily abnormal in any sense other than statistically. Nonetheless, they are indicators of probable pathosis. Sometimes the underlying cause is obvious; in other cases, challenging differential diagnosis is required to determine what is wrong and thus how to treat it.

A cutoff or threshold is a limit used for binary classification, mainly between normal versus pathological (or probably pathological). Establishment methods for cutoffs include using an upper or a lower limit of a reference range.

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Reference range

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In medicine and health-related fields, a reference range or reference interval is the range or the interval of values that is deemed normal for a physiological...

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Reference ranges for blood tests

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Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from...

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Reference ranges for urine tests

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Reference ranges for urine tests are described below: Reference range Reference ranges for blood tests Simerville JA, Maxted WC, Pahira JJ (March 2005)...

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Reference point

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of reference Reference point, a point within a reference range or reference interval, which is a range of values found in healthy persons Reference point...

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Liver function tests

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factors. Individual results should always be interpreted using the reference range provided by the laboratory that performed the test.[citation needed]...

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List of reference ranges for cerebrospinal fluid

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Following is a list of reference ranges for cerebrospinal fluid: PATHOLOGY 425 CEREBROSPINAL FLUID [CSF] Archived 2005-10-27 at the Wayback Machine at...

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Reference electrode

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can be used as a reference. Most electrodes work over a limited range of conditions, such as pH or temperature, outside of this range the electrodes behavior...

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Base excess

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a deficit. A typical reference range for base excess is −2 to +2 mEq/L. Comparison of the base excess with the reference range assists in determining...

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Complete blood count

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diagnose diseases. The results are interpreted by comparing them to reference ranges, which vary with sex and age. Conditions like anemia and thrombocytopenia...

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Thyroid function tests

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actual increase in hormonal activity of thyroid hormones. Reference ranges: Reference ranges: Transthyretin (prealbumin) Albumin Thyroid hormone uptake...

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Red blood cell distribution width

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size. Higher RDW values indicate greater variation in size. Normal reference range of RDW-CV in human red blood cells is 11.5–15.4%. If anemia is observed...

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Prolactin

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gonadotropic hormones is more important. Prolactin within the normal reference ranges can act as a weak gonadotropin, but at the same time suppresses...

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Hypochromic anemia

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defined as below the normal MCH reference range of 27–33 picograms/cell in adults or below the normal MCHC reference range of 33–36 g/dL in adults. Red blood...

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Arterial blood gas test

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metabolic disorder. These are typical reference ranges, although various analysers and laboratories may employ different ranges. Contamination of the sample with...

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Alanine transaminase

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μkat. While sources vary on specific reference range values for patients, 0-40 IU/L is the standard reference range for experimental studies. Test results...

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Human serum albumin

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cleaved in the Golgi apparatus to produce the secreted albumin. The reference range for albumin concentrations in serum is approximately 35–50 g/L (3.5–5...

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Transferrin

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An example reference range for transferrin is 204–360 mg/dL. Laboratory test results should always be interpreted using the reference range provided by...

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White blood cell

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tb01489.x. PMID 5635603. S2CID 45703201. Specific references are found in article Reference ranges for blood tests#White blood cells 2. Wikimedia Commons...

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Serum total protein

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analysers along with other laboratory tests.[citation needed] The reference range for total protein is typically 60-80g/L. (It is also sometimes reported...

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Erythrocyte sedimentation rate

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16–8. doi:10.1177/014107689709000106. PMC 1296109. PMID 9059375. "Reference range (ESR)". GPnotebook. Miller A, Green M, Robinson D (January 1983). "Simple...

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Estradiol

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menstrual cycle and reference ranges widely vary from source to source. Estradiol levels are minimal and according to most laboratories range from 20 to 80 pg/mL...

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Bilirubin

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Medscape Reference. 4 March 2019. Retrieved 6 May 2019. "Bilirubin: Reference Range, Interpretation, Collection and Panels". Medscape Reference. 1 February...

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Reference desk

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The reference desk or information desk of a library is a public service counter where professional librarians provide library users with direction to...

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Philosophy of language

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Investigations may include inquiry into the nature of meaning, intentionality, reference, the constitution of sentences, concepts, learning, and thought. Gottlob...

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Elevated alkaline phosphatase

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phosphatase occurs when levels of alkaline phosphatase (ALP) exceed the reference range. This group of enzymes has a low substrate specificity and catalyzes...

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Reference circuit

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several types of reference circuits are defined, with different configurations, because communications are required over a wide range of distances. Another...

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Parenthetical referencing

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specific page number in a note; page range in a bibliography entry Digital object identifier Examples of book references are: Smith, J. (2005a). Dutch Citing...

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Glycated hemoglobin

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a target range of HbA1c values. A diabetic person with good glucose control has an HbA1c level that is close to or within the reference range.[citation...

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