The PRIDE (PRoteomics IDEntifications database) is a public data repository of mass spectrometry (MS) based proteomics data, and is maintained by the European Bioinformatics Institute as part of the Proteomics Team.[1]
Originally designed by Lennart Martens in 2003 during a stay at the European Bioinformatics Institute as a Marie Curie fellow of the European Commission in the "Quality of Life" Programme (Contract number: QLRI-1999-50595), PRIDE was established as a production service in 2005.[2] The original grant application document from June 2013 to start construction of PRIDE has since been published in a viewpoint article.[3][4] Several similar proteomics databases have been built, including the GPMDB, PeptideAtlas, Proteinpedia and the NCBI Peptidome.[1]
The PRIDE database constitutes a structured data repository, and stores the original experimental data from the researchers without editorial control over the submitted data.
In total, PRIDE contains data from about 60 species, the biggest fraction of it coming from human samples (including the data from the two draft human proteomes[5][6]) followed by the fruit fly Drosophila melanogaster and mouse.[1]
^"Application for Training at the EMBL-EBI EU Marie Curie Training Site" (PDF).
^Martens, Lennart (March 2016). "Public proteomics data: how the field has evolved from sceptical inquiry to the promise of in silico proteomics". EuPA Open Proteomics. 11: 42–44. doi:10.1016/j.euprot.2016.02.005. PMC 5988554. PMID 29900110.
^Wilhelm, M; Schlegl, J; Hahne, H; Moghaddas Gholami, A; Lieberenz, M; Savitski, MM; Ziegler, E; Butzmann, L; Gessulat, S; Marx, H; Mathieson, T; Lemeer, S; Schnatbaum, K; Reimer, U; Wenschuh, H; Mollenhauer, M; Slotta-Huspenina, J; Boese, JH; Bantscheff, M; Gerstmair, A; Faerber, F; Kuster, B (29 May 2014). "Mass-spectrometry-based draft of the human proteome". Nature. 509 (7502): 582–7. Bibcode:2014Natur.509..582W. doi:10.1038/nature13319. PMID 24870543. S2CID 4467721.
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