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Proteoglycan 4 information


PRG4
Identifiers
AliasesPRG4, CACP, HAPO, JCAP, MSF, SZP, bG174L6.2, proteoglycan 4
External IDsOMIM: 604283; MGI: 1891344; HomoloGene: 130465; GeneCards: PRG4; OMA:PRG4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005807
NM_001127708
NM_001127709
NM_001127710
NM_001303232

NM_001110146
NM_021400

RefSeq (protein)

NP_001121180
NP_001121181
NP_001121182
NP_001290161
NP_005798

NP_001103616
NP_067375

Location (UCSC)Chr 1: 186.3 – 186.31 MbChr 1: 150.45 – 150.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Proteoglycan 4 or lubricin is a proteoglycan that in humans is encoded by the PRG4 gene.[5][6][7] It acts as a joint/boundary lubricant.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116690 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000006014 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Marcelino J, Carpten JD, Suwairi WM, Gutierrez OM, Schwartz S, Robbins C, et al. (November 1999). "CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome". Nature Genetics. 23 (3): 319–22. doi:10.1038/15496. PMID 10545950. S2CID 32556762.
  6. ^ Flannery CR, Hughes CE, Schumacher BL, Tudor D, Aydelotte MB, Kuettner KE, Caterson B (January 1999). "Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and Is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism". Biochemical and Biophysical Research Communications. 254 (3): 535–41. doi:10.1006/bbrc.1998.0104. PMID 9920774.
  7. ^ a b "Entrez Gene: PRG4 proteoglycan 4".

and 21 Related for: Proteoglycan 4 information

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Proteoglycan 4 or lubricin is a proteoglycan that in humans is encoded by the PRG4 gene. It acts as a joint/boundary lubricant. Lubricin is present in...

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Lo, Ian K. Y.; Thornton, Gail M. (2016-02-08). "Increased lubricin/proteoglycan 4 gene expression and decreased modulus in medial collateral ligaments...

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melanoma-related antigen (later, it is called, Chondroitin Sulfate Proteoglycan-4 (CSPG4)) by producing a monoclonal antibody. In addition, he produced...

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